Win Ratio in Real-world Heart Failure: Integrating Propensity Scores and Causal Inference for Asian...

Composite endpoints in heart failure (HF) trials enhance power, but often obscure clinical relevance. The win ratio (WR) offers a hierarchical, patient-centred

Atrial Septal Defect in Pregnancy: Clinical Scenarios and Recommendations from the 2025 European...

Atrial septal defect (ASD) is one of the most common congenital heart defects encountered in women of reproductive age. The physiological demands of pregnancy, including increased blood volume

Early Outcomes of Acute Type A Aortic Dissection Treatment According to the Stanford Classification...

Background: Acute Stanford type A aortic dissection is a life-threatening condition with rapidly escalating mortality, requiring urgent surgical

Clinical and Genetic Determinants of Subclinical Coronary Atherosclerosis in Healthy Asian People

Background: Genetic determinants may offer incremental value over routine clinical risk factors for the prediction of coronary atherosclerosis, possibly with different outcomes across

Synchronous Cardiocerebral Infarction as Initial Presentation of Patient with Essential Thrombocy...

Essential thrombocythaemia (ET) is a rare myeloproliferative neoplasm marked by clonal thrombocytosis and increased risk of both arterial and venous

Risk Factors for Higher Cardiovascular Disease Prevalence in Asian Immigrants in the UK: A System...

Introduction: The risk of coronary artery disease (CAD) is significantly higher in South Asians compared to other ethnicities worldwide. Several studies have investigated the reasons behind

How Applicable is the 2025 Focused Update of the 2019 ESC/EAS Guidelines for the Management of...

Asian Pacific Society of Cardiology Consensus Statements on the Use of Transcatheter Edge-to-edge...

Since the publication of the 2021 Asian Pacific Society of Cardiology (APSC) consensus statements on the use of MitraClip for mitral regurgitation (MR), other transcatheter edge-to-edge repair

Interplay of Femoral Arterial Inflammation, Atheroma, Blood Flow and Microvascular Perfusion in...

Background: Diabetic peripheral arterial disease (PAD) involves complex pathophysiology, including accelerated atherosclerosis and impaired microvascular blood

First Philippine Transcatheter Valve-in-valve Implantation in a Surgically-implanted Trifecta...

Redo valve surgery after surgical aortic valve replacement (SAVR) is high risk; transcatheter aortic valve replacement (TAVR) is an alternative. The Trifecta valve (Abbott) is not ideal because

LDL Cholesterol Goal Attainment and Statin Intensity Profile Among Patients with Atherosclerotic...

Background: In Indonesia, cardiovascular disease (CVD) is a major cause of mortality, with atherosclerotic CVD ranking as the country’s top killer. However, research on dyslipidaemia

Specialised Multidisciplinary Heart Failure Clinic in a Middle-income Country: A Single-centre...

Background: Heart failure (HF) is a leading cause of morbidity and mortality globally, with Southeast Asia seeing a rising disease burden. Multidisciplinary HF clinics (MDHFCs) offer a

Comparison Between Cardioneuroablation and Pacemaker Therapy in Patients with Functional Bradycardia

Background: This study sought to examine the efficacy and safety of cardioneuroablation (CNA) and pacemaker (PM) therapy in patients with functional

Comparison of the Prevalence of Hypertension Using Three Proposed Criteria: Single-centre Study...

Background: The prevalence of hypertension can differ depending on the definition used. Hence, this study determined the prevalence of hypertension, including blood pressure (BP) distribution

Guideline-directed Medical Therapy and Outcomes in Heart Failure with Reduced Ejection Fraction: A...

Background: In Sarawak, Malaysia, non-cardiologist physician-led heart failure (HF) clinics were established to improve uptake of guidelinedirected medical therapy

Cardiac CT-guided versus Intravascular Ultrasound-guided Percutaneous Coronary Intervention for...

Background: Intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) is recommended for complex lesions, but has limited adoption due to cost and procedural time