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👋Channelomics.bsky.social👋 @Channelomics

We love ion channels so much we've dedicated a twitter feed 2 them. @ us ur ion channel papers 4a RT. We don't sell stuff! Hoping 2go now where the sky is blue.

Joined February 2012
  • Tweets 6,338
  • Following 1,535
  • Followers 2,680
429 Photos and videos
FYI information, the @Channelomics .bsky.social Ion Channel feed is now flowing, this means if you follow us on there, any post you make (on that platform) including #ionchannel will be added to the Ion Channel feed. bsky.app/profile/did:plc:f57…
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Pharmacological and molecular characterization of a chalcone analogue derived from a Senecio nutans metabolite: Modulation of CaV1.2 and KCa1.1 channels in hypertensive rats - Asunción‐Alvarez - British Journal of Pharmacology ift.tt/X7rUfaI via Mastodon
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Brain voltage-gated Ca2 channels and calmodulin: Teaming up in calmodulinopathies? | Journal of General Physiology | Rockefeller University Press ift.tt/SoltI5e via Mastodon
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Structural determinants at KCNE4 position 145 govern Kv1.3 channel function | Journal of General Physiology | Rockefeller University Press ift.tt/zlnkxs4 via Mastodon
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Evolution of our understanding of the sodium channel fast inactivation: From Hodgkin and Huxley to the structural era | Journal of General Physiology | Rockefeller University Press ift.tt/3Ud14go

Evolution of our understanding of the sodium channel fast inactivation: From Hodgkin and Huxley to...

This is a Review that covers the main advances in our understanding of fast sodium channel inactivation since the original work of Hodgkin and Huxley to th

rupress.org
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GPR35 modulates NaV1.9 #IonChannels in sensory neurons. Cromolyn disodium directly activates GPR35, but zaprinast and sildenafil also require GPR35, together shaping NaV1.9 gating and neuronal excitability. bpspubs.onlinelibrary.wiley.…

BPS Publications

Proposed model in which GPR35 modulates NaV1.9 in sensory neurons. Cromolyn disodium directly activates GPR35, whereas zaprinast and sildenafil implicate a cGMP-associated pathway that also requires...

bpspubs.onlinelibrary.wiley.com
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👋Channelomics.bsky.social👋 retweeted
Hiroki R. Ueda@hiroking1975
Jun 11
#拡散希望　東京大学大学院医学系研究科システムズ薬理学教室では助教1名（あるいは講師１名）を公募しています。睡眠の仕組みや機能 or 覚醒/意識の仕組みや機能に興味があり、哺乳類やヒトを対象とした研究・教育に意欲ある方を歓迎します。締切：2026/9/3必着。詳細は→sys-pharm.m.u-tokyo.ac.jp/pd…
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Muffing the post here (sorry)!I guess this is an #ionchannel?ift.tt/1ZKPSLG via Mastodon
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Prevention of microglial activation and postoperative cognitive deficits by positive allosteric modulation of α5‐GABAA receptors - Lyu - British Journal of Pharmacology - Wiley Online Library ift.tt/fykPOi1 via Mastodon
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Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries - Donovan - British Journal of Pharmacology ift.tt/rzo3qID via Mastodon
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Mechanism of conductance control and neurosteroid binding in NMDA #IonChannel receptors | Nature Sorry it is paywalled…. But look at the beautiful channels 🥲ift.tt/paZx3q7 via Mastodon
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Deletion of the TRPV1 #Ionchannels attenuates afferent renal nerve responses to renal artery occlusion but not elevated renal pelvic pressurehttps://physoc.onlinelibrary.wiley.com/doi/10.1113/JP289721?af=R via Mastodon
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Substrate stiffness attenuates cardiomyocyte depolarization slope via sodium channel modulation (Increased stiffness of the substrate causes the dysfunction of Nav1.5 #Ionchannel kinetics) ift.tt/uwRWsPf via Mastodon
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Sclareol and cinnarizine are non-selective inhibitors of voltage-gated Cav1.3 L-type Ca2 #ionchannels Open access. ift.tt/ag4q7LE via Mastodon
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Mouse retinal ganglion cells and night blindness | TRPM1 #ionchannels, mGluR6 of retinal ON bipolar cellsJ.General Physiol. ift.tt/wLsXrpg via Mastodon
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Aberrant HCN4 #ionchannel expression: Impacts on neuronal excitability and implications for epilepsy pathogenesis - Spyrou - British Journal of Pharmacology Paywalled ift.tt/C58Hw1p via Mastodon
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Piezo1 #ionchannels regulate the mechanotransduction of soft matrix viscoelasticity | Nature Communications nature.com/articles/s41467-0… via Mastodon
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Massive reduction of RyR1 #Ionchannel in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis - Ruiz - The Journal of Physiologyhttps://physoc.onlinelibrary.wiley.com/doi/10.1113/JP287832?af=R via Mastodon
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Augmenting AMPA #IonChannel signaling after spinal cord injury increases ependymal-derived neural stem/progenitor cell migration and promotes functional recovery - Nature Neuroscience ift.tt/e584vOo via Mastodon
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Curious… what’s up?#IonChannelsExpression of Concern ift.tt/TcMmgzo via Mastodon
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Voltage-gated sodium #IonChannels: Mechanisms, disease, and a growing research community *Special Issue* Journal of General Physiology. ift.tt/O0t43e2 via Mastodon
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