In pursuit of the exceptions. Early-stage VC backing technical founders harnessing the accelerating forces of data and computing.

Joined October 2025
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Introducing Deviation Capital. Era-defining companies are the exception. They break almost every rule of conventional wisdom as they rise, but start the same way. A founder encounters something broken, invents a way forward others couldn't see, and bets everything on bringing it to life. We launch today as the spinout of Two Sigma Ventures to find, fund, and support these founders, backing technical teams harnessing data and computing to build enduring exceptions.
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Today, we are excited to announce TerraSynth, the latest addition to Terray's EMMI platform. Synthesizing AI-generated molecules is a key bottleneck in modern small-molecule drug discovery. We built TerraSynth to fix that. TerraSynth is a generative synthesis planner that proposes new molecules together with a recipe for making them, keeping the DMTA cycle moving efficiently. *TerraSynth covers 67% more chemical space than the next best synthesis planner, at 1/1000th of the cost. *TerraSynth is fast to inference, and can be run directly inside the design loop, ensuring that every proposed compound has been optimized for synthesizability. *TerraSynth has prospectively reduced synthesis time for molecules synthesized at Terray by up to 75%. TerraSynth is being used in real programs at Terray every day. To read more about how we built this model and the key results, check out the blog terraytx.ai/news-and-researc…
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My favorite thing about technology is when it makes our real lives better in tangible ways. Luma, the new offering from Highbeam, does this by empowering D2C brands to stop worrying so much about cash and finance (which every small business owner will tell you they spend way too much time on), and focus more of their time and energy on the reason they started their business in the first place - which is BUILDING THE PRODUCTS THAT THEIR CUSTOMERS LOVE, the things that make their everyday lives better. AI is a massively enabling technology when harnessed correctly, which is what Luma does. Check it out.
Introducing Luma, a world-class finance team for D2C. Most AI in finance focuses on tasks. Luma focuses on decisions. Built on $15B of consumer brand transaction volume. Proud of our team at Highbeam. Check it out: highbeam.com/luma
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We've selected @Honeywell_Aero's TPE331 turboprop engine to power our large-scale, multimission Group 5 UAS. As you can see from the video below - the first propulsion systems have already been supplied with many more to come. In many ways, an aircraft is designed around its powerplant. The TPE331 brings six decades of refinement, 13,000 engines delivered, and 122 million flight hours across military, commercial, and agricultural aviation. Pairing that proven performance with Swarm's next-generation multimission vehicle is how we're ensuring we can deliver on the urgent needs of our customers. Read the full announcement here. globenewswire.com/news-relea…
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New York venture firms are broadening their geographic reach. Examples: Primary, Work-Bench, and Deviation (formerly Two Sigma) Part of the reason: AI mania in SF is hard to ignore. NY seed investing declined as a share of total in the U.S. last year. wsj.com/pro/venture-capital/…
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.@WHOOP won the wearables game . . . and now more competitors are coming for the king. Founder and CEO @willahmed and company on how its data goldmine, cult-fan users, and evolution from fitness to health are going to keep it ahead of startups & Google inc.com/ashwin-rodrigues/big…
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This kind of hustle and complex regulatory wrangling and relentless customer focus is one of those increasingly rare moats investors love! 😍 @remote
Big announcement today at @remote! We are going all in on 𝗴𝗹𝗼𝗯𝗮𝗹 𝗽𝗮𝘆𝗿𝗼𝗹𝗹 𝗮𝗻𝗱 𝗲𝗺𝗽𝗹𝗼𝘆𝗺𝗲𝗻𝘁 𝗶𝗻𝗳𝗿𝗮𝘀𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗲, and opening our platform to the world. Sounds simple until you try to build it: Payroll in one country is already a dense topic. Payroll across the world becomes an insane systems problem: tax laws, social security, benefits, holidays, languages, currencies, equity, and local interpretations that change because a government updated a rule somewhere. When we started Remote, my engineer brain thought we would plug into the payroll APIs that existed around the world. They mostly did not exist, so we did the hard work. We set up entities. We built in-house payroll engines. We documented compliance country by country. We learned the local details that make payroll work in practice. It took seven years. It took a lot of investment. It took a lot of people doing important work. Today we are opening that infrastructure up. Any company, any tool, any workflow, any AI agent can plug into Remote and use the global payroll and employment infrastructure we have built. You keep your systems. We handle the hard parts: payroll, compliance, employment infrastructure, country by country. I am grateful to our team, our customers, our partners, and everyone who supports us along the way. Seven years building toward this chapter. The best is yet to come. Let’s go. Full story: okt.to/VOw785
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For as long as I can remember, I've wanted this job. Apple's "Think Different" posters covered every wall of my teenage bedroom. I got my first taste of venture at Greylock, I learned how to build at Airbnb as their first product manager, scaling with them as they 100x'd over every metric, and I partnered with truly exceptional founders at NEA. At Deviation Capital, I get to build and invest. @csbeirne, Dusan, Sidney and I started @Deviationcap to find and support the founders operating at the frontier and in the fringes, harnessing data, computing, and AI to build the defining companies of our time. We're hiring in SF –– reach out.
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Two Sigma Ventures has spun out of the hedge fund and is now operating as Deviation Capital. It's raising a $300 million fund, per a source wsj.com/pro/venture-capital/… via @WSJ
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Introducing Deviation Capital. Era-defining companies are the exception. They break almost every rule of conventional wisdom as they rise, but start the same way. A founder encounters something broken, invents a way forward others couldn't see, and bets everything on bringing it to life. We launch today as the spinout of Two Sigma Ventures to find, fund, and support these founders, backing technical teams harnessing data and computing to build enduring exceptions.
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You can learn more about the full portfolio at deviation.com/#companies
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