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JAMA Network Open @JAMANetworkOpen

JAMA Network Open is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

Joined April 2017
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  • Followers 25,984
4,691 Photos and videos
📣 Presented this year at #CCR26: Remote monitoring after hospitalization for #sepsis or respiratory infection did not increase home days and reduced home days for adults ≥65 years, compared with usual care. #CCR26 @CritCareReviews ja.ma/3Qeobhu
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County-level analysis found no significant association between state point-of-sale comprehensive #BackgroundCheck policies and firearm homicide rates, with adjusted estimates close to zero. ja.ma/43vLl60
Line graph shows crude firearm homicide rate per 100,000 population from 2000-2021 for Colorado, Delaware, New Mexico, Oregon, Vermont, Washington, and Comparison states. Rates generally increased over time, with New Mexico reaching over 12 in 2021.

ALT Line graph shows crude firearm homicide rate per 100,000 population from 2000-2021 for Colorado, Delaware, New Mexico, Oregon, Vermont, Washington, and Comparison states. Rates generally increased over time, with New Mexico reaching over 12 in 2021.
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Among patients with community-onset #Sepsis, receiving ≥30 mL/kg fluid within 6 hours was linked to lower 30-day mortality, most notably for hypoperfusion and intermediate lactate elevation without severe comorbidities. ja.ma/4gg0gsq
Three line graphs show fluid received (mL) per 30 mL/kg bolus vs. BMI (15-55) for average male (higher) and female (lower) heights. A: Fluid increases stepwise with BMI. B: Fluid increases to BMI 30, then drops sharply and caps. C: Fluid increases to BMI 30, then caps.

ALT Three line graphs show fluid received (mL) per 30 mL/kg bolus vs. BMI (15-55) for average male (higher) and female (lower) heights. A: Fluid increases stepwise with BMI. B: Fluid increases to BMI 30, then drops sharply and caps. C: Fluid increases to BMI 30, then caps.

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Comorbidity coding rates and mortality associations changed for Medicare fee-for-service and Medicare Advantage post-pandemic, affecting risk adjustment and policy analyses. ja.ma/3QEaKaC
Line graph showing \"Number of CCWs\" (Y-axis) from 2018-2023 (X-axis). Two \"Enrollment\" lines: blue (MA) is higher, fluctuating between 4.3 and 4.6; orange (FFS) is lower, between 3.7 and 3.9. Vertical lines mark 2019 & 2022.

ALT Line graph showing \"Number of CCWs\" (Y-axis) from 2018-2023 (X-axis). Two \"Enrollment\" lines: blue (MA) is higher, fluctuating between 4.3 and 4.6; orange (FFS) is lower, between 3.7 and 3.9. Vertical lines mark 2019 & 2022.
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Among adults in communities affected by #MassViolence, 65.5% worried about future incidents and 28.5% avoided public places, with odds rising alongside media consumption. ja.ma/3Qc9SKk
Line graph: Log odds of worry vs. media consumption. Orange line 'No social media' (Exp(b)=1.43, P<.001) shows worry increasing from near 0 to 1.4. Gray line 'Use of social media' (Exp(b)=1.23, P<.001) shows worry increasing from 0.4 to 1.3. Both show higher worry with more consumption.

ALT Line graph: Log odds of worry vs. media consumption. Orange line 'No social media' (Exp(b)=1.43, P<.001) shows worry increasing from near 0 to 1.4. Gray line 'Use of social media' (Exp(b)=1.23, P<.001) shows worry increasing from 0.4 to 1.3. Both show higher worry with more consumption.
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#Diabetes and cumulative CVD risk factors were associated with #VisualImpairment, especially by best-corrected visual acuity, while social factors like low income and limited health care access also correlated with higher rates. ja.ma/4v6n8iL
Four graphs show health prevalences by Hispanic/Latino background. Top graphs (A, B) show diabetes prevalence for men & women, with Puerto Rican groups often highest. Bottom graphs (C, D) display cumulative CVD risk factors for men & women across categories.

ALT Four graphs show health prevalences by Hispanic/Latino background. Top graphs (A, B) show diabetes prevalence for men & women, with Puerto Rican groups often highest. Bottom graphs (C, D) display cumulative CVD risk factors for men & women across categories.
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NIH invested over $95 million in 81 projects on #UltraprocessedFoods from 2016 to 2025, with most research linking ultraprocessed food intake to #Obesity and #Diabetes, but few studies testing interventions in food environments. ja.ma/3QhNUFx
Bar and line graph showing Total dollars awarded and Projects per fiscal year from 2016-2025. Dollars awarded generally rose from 2016 to a peak in 2024, then fell in 2025. Projects per year fluctuated, peaking in 2021 and 2023, then decreasing.

ALT Bar and line graph showing Total dollars awarded and Projects per fiscal year from 2016-2025. Dollars awarded generally rose from 2016 to a peak in 2024, then fell in 2025. Projects per year fluctuated, peaking in 2021 and 2023, then decreasing.
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LA-ART use among Medicare beneficiaries with #HIV increased modestly to 3% by 2023, with lower uptake in older adults, American Indian or Alaska Native individuals, rural areas, and the South. ja.ma/4eE8F7K
JAMA Network Open article titled \"Long-Acting Injectable Antiretroviral Therapy in Medicare-Enrolled Adults With HIV.\" It's a Research Letter in Infectious Diseases, published online June 12, 2026. Authors include Jose F. Figueroa.

ALT JAMA Network Open article titled \"Long-Acting Injectable Antiretroviral Therapy in Medicare-Enrolled Adults With HIV.\" It's a Research Letter in Infectious Diseases, published online June 12, 2026. Authors include Jose F. Figueroa.
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A telemedicine diabetes clinic for incarcerated men was associated with improved glycemic control, weight loss, and greater rates of recommended screenings over 18 months. ja.ma/4opzWhI
JAMA Network Open article: 'Telemedicine-Based Diabetes Management for Incarcerated Individuals.' A Research Letter in Diabetes and Endocrinology by Julio A. Rebolledo et al., published online June 12, 2026. DOI: 10.1001/jamanetworkopen.2026.18695

ALT JAMA Network Open article: 'Telemedicine-Based Diabetes Management for Incarcerated Individuals.' A Research Letter in Diabetes and Endocrinology by Julio A. Rebolledo et al., published online June 12, 2026. DOI: 10.1001/jamanetworkopen.2026.18695
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In this RCT, 1% chlorhexidine provided effective, safe bacterial reduction in both mothers and neonates, supporting its use in future infection-prevention trials. ja.ma/43s4UMz
Four graphs show mean log10CFU over 48h. Maternal population (top): Antiseptics reduce CFU (2% CHG best); multiple applications keep CFU lower. Neonatal population (bottom): CFU generally increases over time for all antiseptics & frequencies.

ALT Four graphs show mean log10CFU over 48h. Maternal population (top): Antiseptics reduce CFU (2% CHG best); multiple applications keep CFU lower. Neonatal population (bottom): CFU generally increases over time for all antiseptics & frequencies.
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Remote monitoring after hospitalization for infection or sepsis did not increase home days vs usual care and was linked to increased readmissions among adults ≥65 years. ja.ma/4uApYeK
Graph A shows postdischarge days home distribution for Usual care and 4 RPM teams. Most patients have many home days (blue bars), few deaths (red). Graph B compares COR (95% Crl) of RPM teams to usual care via a forest plot. RPM-low enhanced team shows slight superiority with COR 1.01 and 52.5% probability.

ALT Graph A shows postdischarge days home distribution for Usual care and 4 RPM teams. Most patients have many home days (blue bars), few deaths (red). Graph B compares COR (95% Crl) of RPM teams to usual care via a forest plot. RPM-low enhanced team shows slight superiority with COR 1.01 and 52.5% probability.

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Hospital water systems were the primary source of Mycobacterium abscessus infection in transplant recipients, with patient strains genetically linked to tap water rather than person-to-person transmission. ja.ma/4fBcfk5
Three phylogenetic trees show MAB subspecies abscessus (A, circular) and massiliense (B, circular) global phylogenies with continent and DCC type. Tree C details DCC7 phylogeny with country/US region data, showing subclones and clusters.

ALT Three phylogenetic trees show MAB subspecies abscessus (A, circular) and massiliense (B, circular) global phylogenies with continent and DCC type. Tree C details DCC7 phylogeny with country/US region data, showing subclones and clusters.
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FDA-authorized AI-enabled medical devices lacking published clinical studies had a higher risk of recall, with use-related problems most frequently triggering recalls. ja.ma/4otRYiY
Flowchart detailing a data processing workflow for 903 AI-enabled medical devices. It starts from CORE-DB, Published dataset (Windecker et al., 2025), and MAUDE. Data undergoes identification, categorization, and variable creation, then combines for filtering, statistical modeling, inference, and scenario-based analysis.

ALT Flowchart detailing a data processing workflow for 903 AI-enabled medical devices. It starts from CORE-DB, Published dataset (Windecker et al., 2025), and MAUDE. Data undergoes identification, categorization, and variable creation, then combines for filtering, statistical modeling, inference, and scenario-based analysis.
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Parental decisions about life-sustaining treatment for children with medical complexity were shaped primarily by caregiving experience, comfort, and dignity, not solely prognosis. ja.ma/4vJQN14.
Table 2 presents clinical characteristics for 8 children with medical complexity, detailing Family No., Gender, Age, Diagnosis (e.g., HIE, Cerebral palsy), Type of impairment, Mobility status, Indwelling tube type, Ventilator dependence, and Oral feeding.

ALT Table 2 presents clinical characteristics for 8 children with medical complexity, detailing Family No., Gender, Age, Diagnosis (e.g., HIE, Cerebral palsy), Type of impairment, Mobility status, Indwelling tube type, Ventilator dependence, and Oral feeding.
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Internet searches for leucovorin and folate rose sharply after a 2025 White House autism announcement, with acetaminophen autism/pregnancy queries rising 13-fold. ja.ma/4oqZHhJ
Five line graphs display search query fractions (per 10M searches) for medical terms, Aug 4-Sept 29. Leucovorin & Folinic acid/folate searches spiked dramatically mid-Sept, as did their purchase queries. Multivitamin searches remained stable.

ALT Five line graphs display search query fractions (per 10M searches) for medical terms, Aug 4-Sept 29. Leucovorin & Folinic acid/folate searches spiked dramatically mid-Sept, as did their purchase queries. Multivitamin searches remained stable.
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Nearly all systemic antifungal clinical trial sites in the US are metropolitan, with just 0.6% of rural residents living within 30 miles of a treatment trial site. ja.ma/4fC5DSw
A graph and two maps show US systemic antifungal trial sites. The bar chart details population (gray bars), treatment trials (blue line), and prophylaxis trials across census divisions. Treatment trials largely align with population. Map B shows numerous treatment sites (red dots), while Map C displays fewer prophylaxis sites (green dots) nationwide.

ALT A graph and two maps show US systemic antifungal trial sites. The bar chart details population (gray bars), treatment trials (blue line), and prophylaxis trials across census divisions. Treatment trials largely align with population. Map B shows numerous treatment sites (red dots), while Map C displays fewer prophylaxis sites (green dots) nationwide.
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Only 0.5% of active interventional sarcoma trials are conducted in South America, and just 2 of 13 sarcoma drug approval trials since 2009 included regional participants. ja.ma/4v83B1x

Representation of Patients From South America in Sarcoma Clinical Trials

This cross-sectional study uses clinical trial data, US and European oncology drug approval data, and health care professional survey data to examine the representation of South American patients in...

jamanetwork.com
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Mass azithromycin administration to infants did not result in improved growth outcomes or reduced undernutrition rates compared with placebo in this large, cluster randomized trial. ja.ma/43ovIx9
Six graphs display z-scores (weight/age, length/age, weight/length) for 6-8mo & 12-14mo infants across Placebo, Twice-yearly, & Quarterly azithromycin treatments (Aug 2022-Jul 2023). Most scores fluctuate, with a general decline towards the end. Azithromycin groups show minor, inconsistent differences from Placebo.

ALT Six graphs display z-scores (weight/age, length/age, weight/length) for 6-8mo & 12-14mo infants across Placebo, Twice-yearly, & Quarterly azithromycin treatments (Aug 2022-Jul 2023). Most scores fluctuate, with a general decline towards the end. Azithromycin groups show minor, inconsistent differences from Placebo.
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CPOE prompts with patient-specific MDRO risk safely reduced empiric extended-spectrum antibiotic use by 17%–27% in hospitalized adults with cancer, with no difference in ICU transfers or mortality. ja.ma/4uvo531
Four line graphs show antibiotic therapy days (per 1000 empiric days) for Pneumonia, UTI, SSTI, & Abdominal infection over study periods. Each compares Routine vs. CPOE extended-spectrum antibiotics. CPOE generally results in fewer therapy days, particularly during the Intervention phases.

ALT Four line graphs show antibiotic therapy days (per 1000 empiric days) for Pneumonia, UTI, SSTI, & Abdominal infection over study periods. Each compares Routine vs. CPOE extended-spectrum antibiotics. CPOE generally results in fewer therapy days, particularly during the Intervention phases.
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During the 2024–2025 season in California, influenza vaccination was linked to a 40% lower risk of lab-confirmed influenza and 29% lower odds of death among adults aged ≥65 years with infection. ja.ma/4eiquYO
Line graph of Test Positivity (%) from Oct 2024 to Jun 2025. Starting at ~2.5%, it peaks around 37% in late Dec, dips, then reaches a higher peak of ~39% in early Feb. It declines to ~6% by June, showing two waves.

ALT Line graph of Test Positivity (%) from Oct 2024 to Jun 2025. Starting at ~2.5%, it peaks around 37% in late Dec, dips, then reaches a higher peak of ~39% in early Feb. It declines to ~6% by June, showing two waves.

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