Oncogene aims to make substantial advances in our knowledge of processes that contribute to cancer by publishing outstanding research.
Joined July 2018
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A novel insight into #lncRNA-mediated reprogramming of the tumour immune #microenvironment
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#ColorectalCancer #CancerResearch
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Could selective ferroptosis inducers, such as R4VPs, be a way to tackle hard-to-treat cancers?
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#OpenAccess @TechnionLive
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How does high-fat diet contribute to #ColorectalCancer development?
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#CancerResearch
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Targeting HIF-1α transcriptional activity with LNP 💊echinomycin disrupts stress-adapted #ColorectalCancer metastatic traits and lung metastasis
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Could a noncoding SNP mediate #LungCancer progression? 🤔
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Novel DAPK3-TIA1-CLSTN1 splicing axis drives #BreastCancer metastasis
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Latest study uncovers a neuro-immune mechanism where chronic stress triggers NETs to promote gastric cancer lymph node metastasis. Read more >>>>
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New research reveals how bone marrow niche signals—via Galectin‑1 and pre‑BCR signalling—cooperate with oncogenic mutations to shape pre‑leukaemic B cell fate and drive B‑ALL development. #LeukaemiaResearch #BcellBiology #BoneMarrow #CancerBiology
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This study uncovers metabolic-epigenetic pathway by which GPX8⁺ cancer‑associated fibroblasts drive lenvatinib resistance in hepatocellular carcinoma, identifying MCT1 and BRPF1 as promising therapeutic targets to overcome treatment failure. Read more nature.com/articles/s41388-0…
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New research reveals circPARPBP as a key driver of #chemoresistance in triple‑negative breast cancer and shows how the natural compound isoliquiritigenin can help overcome treatment resistance.
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New study discovers a circadian mechanism linking NDRG2‑mediated CLOCK stabilisation to suppressed tumour growth and improved oxaliplatin response in colorectal cancer.
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Microbes aren’t passengers in prostate disease—but their impact depends on timing. This Review reveals when microbial signals matter, and when they don’t.
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This study identifies a GBP2–GSDMD–YAP signalling axis that limits immune evasion in #colorectal cancer by suppressing YAP-mediated repression of CXCL9/10/11, thereby enhancing CD8⁺ T‑cell infiltration. Read more :
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New study uncovers how RNA regulatory axis fuels ovarian cancer: the SNRPD2–CPSF7–UBE2K pathway links splicing and polyadenylation to tumour growth—and opens the door to new therapies.
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New study reveals that the ribosomal protein RPS15 plays a key non‑traditional role in promoting prostate cancer progression and metastasis through the DDX21–SCD1 pathway. Read more >>>>
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Modulation of gut microbiota🦠has the potential to enhance the efficacy of anti-PD-1/PD-L1 immunotherapy in #HepatocellularCarcinoma
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#Microbiome #Immunotherapy #HCC
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A dual role for VPS4 inhibition in inducing tumour cell death and promoting anti-tumour immunity in #rhabdomyosarcoma
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#OpenAccess
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Could tumour-colonizing 🦠bacteria be harnessed for therapeutic purposes? 🤔
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iPalmT 👉 an end-to-end deep learning framework that identifies palmitoyltransferasesfrom primary amino acid sequence
Learn more here:
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Could Sirt1 be a potential therapeutic target for SHH-driven #Medulloblastoma?
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