The Cardiovascular-Kidney-Metabolic Syndrome Guideline will reshape CKM syndrome prevention and care.

Brain health is shaped by cumulative environmental exposures. This paper examines how prenatal, early-life, and adult exposures to air pollution and toxicants are associated with impaired neurodevelopment, cognitive decline, and dementia risk.

Published today, the first-ever clinical practice guideline on cardiovascular-kidney-metabolic syndrome from the American Heart Association and @ACCinTouch. Cardiovascular-kidney-metabolic (CKM) syndrome staging is recommended for youths and adults to prevent CKM syndrome stage progression, to tailor therapy to absolute risk, to reduce cardiovascular events and loss of kidney function across the life course, and to promote CKM syndrome stage regression through lifestyle changes and weight loss. The diagnosis of CKM syndrome stage requires assessment of metabolic health, kidney function, and cardiovascular risk factors, which enhances the identification of frequently unrecognized or asymptomatic CKM conditions. ✍🏼 @ChiadiNdumele @HeartDocSadiya @kardiologykazi @noshreza @virani_md @biykemb @NutritionHF @mandeepbajaj65 @KatherineTuttl8 @RangaswJ @lisaVWMD @KBreathettMD @EmoryFamMed @ShoaClarke @mad_sters @jmortonmd @sripalbangalore @AnumSaeedMD

Progression along the spectrum of cardiovascular-kidney-metabolic (CKM) syndrome stages is accompanied by increasing absolute risk of cardiovascular disease. This framework highlights the cumulative and progressive nature of CKM-related risk. 📷 Conceptual crosswalk between absolute risk of cardiovascular disease and cardiovascular-kidney-metabolic syndrome stages ✍🏼 @HeartDocSadiya @RangaswJ @pnatarajanmd @dramitkhera @NicoleBhaveMD @yuan_lu1 @rblument1 @JenHoCariology @virani_md @ChiadiNdumele

The 2026 AHA/ACC/ADA/ASN CKM Guideline recommends the use of the PREVENT equations to (1) define CKM syndrome stage 3, (2) decide when to test for subclinical cardiovascular disease; and (3) guide risk-based decision making for CKM therapies. This scientific statement serves as a companion to this guideline and details the rationale for the use of outcome-specific PREVENT equations, the evidence base for selected risk thresholds, and the potential population-level impact of these recommendations. ✍🏼 @HeartDocSadiya @RangaswJ @pnatarajanmd @dramitkhera @NicoleBhaveMD @yuan_lu1 @rblument1 @JenHoCariology @virani_md @ChiadiNdumele

Published today, the first-ever clinical practice guideline on cardiovascular-kidney-metabolic (CKM) syndrome from the American Heart Association and @ACCinTouch. The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of CKM syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients. ✍🏼 @ChiadiNdumele @HeartDocSadiya @kardiologykazi @noshreza @virani_md @biykemb @NutritionHF @mandeepbajaj65 @KatherineTuttl8 @RangaswJ @lisaVWMD @KBreathettMD @EmoryFamMed @ShoaClarke @mad_sters @jmortonmd @sripalbangalore @AnumSaeedMD

Early career professionals: Kick things off at our BCVS Council webinar on June 9, then join us at #BCVS26 (July 13–16, Boston) for: ▪️Pre-Conference (Keynote: Dr. Sumanth Prabhu) ▪️ Mentoring networking ▪️ Awards career events

Cardiovascular disease remains the leading cause of death in the United States, accounting for more deaths than cancer and chronic respiratory diseases combined. Most deaths from CVD are related to coronary heart disease, but heart failure, hypertension, vascular disease and arrhythmias contribute to the high burden. See the latest in the 2026 Statistics Update.

📣 Deadline Extended! Submit your #ScientificSessions26 and #ReSS26 abstracts by June 8th and get your research in front of the community. Scientific Sessions 2026 Chairs: @JoChikweMD @bnallamo ReSS 2026 Chairs: @Dezfulian_CCM @sarahmperman

Depression and anxiety are not isolated conditions. This paper examines how the timing of depression across the life course may influence dementia risk and brain structure, reinforcing the need for earlier intervention.