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eLife - the journal @eLife

The funder-researcher collaboration and open-access journal for research in the life and biomedical sciences | @eLifeCommunity

Joined September 2011
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A quantitative pipeline for whole-mount deep imaging and analysis of multi-layered organoids across scales elifesciences.org/articles/1…
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The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot elifesciences.org/articles/1…

The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot

Within the nucleus accumbens shell, a spatially defined rostral subregion selectively modulates hedonic feeding, revealing functional heterogeneity in reward circuitry underlying food consumption.

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Cognitive simplicity drives collective route improvements in homing pigeons elifesciences.org/articles/1…

Cognitive simplicity drives collective route improvements in homing pigeons

A navigational model exploring social learning strategies differing in cognitive complexity in homing pigeons shows that simple averaging sufficiently explains collective route improvements, without...

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Rolling with the seasons elifesciences.org/digests/10…

Rolling with the seasons

Autumn timing in temperate deciduous trees is controlled by both developmental stage and seasonal temperature cues, with late-summer cooling overriding earlier developmental differences.

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High-fidelity neural speech reconstruction through an efficient acoustic-linguistic dual-pathway framework elifesciences.org/articles/1…

High-fidelity neural speech reconstruction through an efficient acoustic-linguistic dual-pathway...

Concurrent decoding of acoustic detail and linguistic structure enables natural, intelligible speech synthesis from limited human cortical recordings, resolving a fundamental constraint in neural...

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Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for stress-induced mechanical pain hypersensitivity elifesciences.org/articles/1…

Descending locus coeruleus noradrenergic signaling to spinal astrocyte subset is required for...

Stress activates a locus coeruleus–spinal dorsal horn noradrenergic circuit that drives mechanical pain hypersensitivity through Hes5-positive astrocytes.

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We publish research in microbiology and infectious disease, including microbiomes, microbial ecology, mycology, pathology, parasitology, and virology. Read the latest research ⬇️ elifesciences.org/subjects/m…
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Peripheral anatomy and central connectivity of proprioceptive sensory neurons in the Drosophila wing elifesciences.org/articles/1…

Peripheral anatomy and central connectivity of proprioceptive sensory neurons in the Drosophila wing

Comprehensive mapping of wing sensory neurons in Drosophila reveals that some proprioceptors make direct connections onto flight steering motor neurons, enabling rapid feedback control during flight.

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Movie reconstruction from mouse visual cortex activity elifesciences.org/articles/1…

Movie reconstruction from mouse visual cortex activity

Naturalistic movie reconstruction from mouse visual cortex activity achieves high spatial and temporal fidelity.

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Precision cutaneous stimulation in freely moving mice elifesciences.org/articles/1…

Precision cutaneous stimulation in freely moving mice

A closed-loop system delivers cutaneous optical stimulation during movement in freely behaving mice, enabling controlled somatosensory input in naturalistic settings.

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Spatially targeted inhibitory rhythms differentially affect neuronal integration elifesciences.org/articles/9…

Spatially targeted inhibitory rhythms differentially affect neuronal integration

Beta and gamma inhibitory rhythms are preferentially tuned to govern synaptic integration in layer 5 pyramidal neurons by differentially modulating responses to inputs targeting distal dendritic and...

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Our annual survey is your chance to have your say on the work we do. Have thoughts about our model for publishing? Share them here: surveymonkey.com/r/7XXTQCN
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From brain databases and deep-learning methods to imaging and genetic modification techniques, eLife Tools and Resources articles present new techniques, datasets, software tools, and more. Take a look a the latest Tools and Resource articles: elifesciences.org/articles/t…
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Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus contrast elifesciences.org/articles/1…

Readout and delayed transmission of initial afferent V1 activity in decisions about stimulus...

Evidence is provided suggesting that aggregate neural activity at an early stage of visual processing (V1) can directly contribute to perceptual decisions in humans.

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Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse brain elifesciences.org/articles/1…

Sex-specific single transcript level atlas of vasopressin and its receptor (AVPR1a) in the mouse...

Using RNAscope mapping provides the comprehensive, sex-specific atlas of vasopressin and its receptor gene expression across the murine brain, refining understanding of how vasopressin signaling is...

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This fundamental work demonstrates that ABHD6 regulates AMPAR gating kinetics in a TARP γ-2-dependent manner. The evidence in this study is compelling. This study will be of interest to readers in the field of synaptic transmission. elifesciences.org/reviewed-p…
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The distinct role of human PIT in attention control elifesciences.org/articles/1…

The distinct role of human PIT in attention control

The human posterior inferotemporal cortex integrates endogenous and exogenous influences to form a unified attentional priority map for adaptive visual control.

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Self-association enhances early attentional selection through automatic prioritization of socially salient signals elifesciences.org/articles/1…

Self-association enhances early attentional selection through automatic prioritization of socially...

Self-related information automatically modulates early attentional selection into awareness through mechanisms distinct from physical salience, revealing an obligatory, individualized self-prioriti...

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Distinct representational properties of cues and contexts shape fear and reversal learning elifesciences.org/articles/1…

Distinct representational properties of cues and contexts shape fear and reversal learning

Fear updating relies on a flexible shift from generalized to item-specific, context-bound neural representations, revealing how the brain adapts to changing threat contingencies and why fear can...

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The Fd4 transcription factor translates transient spatial cues in progenitors into long-term lineage identity elifesciences.org/articles/1…

The Fd4 transcription factor translates transient spatial cues in progenitors into long-term...

Fd4 is expressed in NB7-1 and new-born progeny where it activates terminal selector genes to produce lineage-specific neurons.

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