Regulus (MASTER) 理論値900回💫💫💫 ー理論値率ー 理論値率: 1 / 6.952 鍵盤理論値率: 1 / 6.771 (鍵盤理論値: 24回) ー連続理論値ー 2連続:182回 3連続:42回 4連続:7回 5連続:1回 ーPSCORE集計ー 理論値時 4160〜:213回 4170〜:43回 ⭐︎5🌈(4178)〜:5回 (理論値以外含む) 遂に、あと100回。

putting my hand on your shoulder i think the twins were probably most of the reason meiko was the pscore there. her meimeis were out

やーっとテトリス詰まった（Pscoreは詰まってない） 最近見知った人も多くなってきたから一応音ゲーの民だよというところは見せておくんよ

pscore has a way better skill than heal or score so they have lower talent

Highly Accurate Estimation of the Fold Accuracy of Protein Structural Models 1 DeepUMQA-Global is presented as an independent single-model estimator for global fold accuracy of protein structural models, targeting a key bottleneck: reliably ranking/selecting the best model among many predictions without relying on the predictor’s own confidence head or large model pools. 2 The central innovation is a structure–sequence cross-consistency mechanism that quantifies bidirectional compatibility: (i) structure-conditioned sequence plausibility and (ii) sequence-conditioned structural priors, aiming to better detect fold-level errors in complex assemblies and interfaces. 3 The method outputs two global scores: pScore for whole-complex accuracy and ipScore for interface accuracy (interfaces defined via inter-chain atoms within 5 Å). Training supervision uses TM-score to emphasize global correctness and practical model ranking. 4 Feature design combines three complementary categories: sequence features (input sequence SAGS SALS), structural features (SASP distance/orientation maps), and physicochemical features (SASA, VTIO, and extensive geometry/energy descriptors including Rosetta terms, torsions, Euler angles, voxelization). 5 Two standout bidirectional features are emphasized: SAGS from ProteinMPNN embeddings (structure→sequence preferences capturing global fold-conditioned residue distributions) and SASP (sequence→structure priors from template-derived distance distributions retrieved using an AlphaFold3-predicted structure as a search query, plus entropy as uncertainty). 6 Architecture processes residue-wise and pairwise information in parallel: a GAT encodes 1D node embeddings over a Cα 15 Å graph; a 2D CNN plus row–column attention encodes 2D pair embeddings; then a gating step uses the single (node) representation to modulate the pair representation before global aggregation into pScore/ipScore. 7 On an AlphaFold3-generated CASP16-derived test (26 complex targets; <3000 residues; excluding two dynamic targets), DeepUMQA-Global reports higher agreement with ground-truth TM-score than AlphaFold3 self-assessment: Pearson 0.453 vs 0.287 ( 57.8%), Spearman 0.371 vs 0.249 ( 49.0%), ROC AUC 0.614 vs 0.568 ( 8.1%); per-target gains occur for most targets. 8 For antibody–antigen complexes (8 targets), it also reports improved ranking over AlphaFold3 self-assessment (Pearson 0.645 vs 0.415; Spearman 0.581 vs 0.369; ROC AUC 0.725 vs 0.633), while noting remaining challenges at flexible immune interfaces (e.g., CDR flexibility and weak coevolution signals). 9 In a CASP16 retrospective EMA benchmark (30 targets after filtering), DeepUMQA-Global ranks as the top single-model method for both SCORE (fold/topology) and QSCORE (interfaces), and is reported to be competitive with consensus-based methods, especially in selecting near-native top models (strong Loss/Top1Loss behavior). 10 A lightweight consensus extension, DeepUMQA-Global-Con, uses DeepUMQA-Global to pick the top 5 models as a reference subset and averages US-align similarities; it is reported to rank first among all CASP16 EMA participants while scaling ~O(N) rather than O(N²) typical of full all-vs-all consensus. 11 Ablations attribute major performance to SASP (largest drop when removed) and SAGS (second-largest), and to the 2D CNN module (largest architectural drop), supporting the claim that combining sequence-conditioned structural priors with structure-conditioned sequence plausibility is key for global accuracy estimation. 12 Beyond static evaluation, the paper tests alternative conformations: on CASP16 target T1249 (closed vs open trimeric spike), DeepUMQA-Global is reported to select strong top models for both states and to discriminate models in mixed-state pools; on 91 CoDNaS apo–holo pairs it yields more consistent state-to-state scores than a prior method (MViewEMA), suggesting potential for dynamic conformation EMA. 📜Paper: biorxiv.org/content/10.64898… #ProteinStructure #CASP16 #AlphaFold3 #ModelQualityAssessment #EMA #ProteinComplexes #DeepLearning #StructuralBiology #ComputationalBiology #Bioinformatics

Regulus (MASTER) PSCORE更新🆙🆙 4180 (MAX-40) ➡︎ 4184 (MAX-36) 最後でHIT出て本当に勿体無いけど やっぱりP更新したときは嬉しい🤩🤩🤩

Regulus (MASTER) 理論値650回 ー理論値率ー 理論値率: 1/6.775 9990 & 理論値率: 1/6.673 (9990: 10回) ー連続理論値ー 2連続:120回 3連続:29回 4連続:6回 5連続:1回 ーPSCORE集計ー 理論値時 ⭐︎5(4136)〜: めちゃめちゃ 4160〜:162回 4170〜:36回 ⭐︎5🌈(4178)〜:3回 (非理論値含む)

what the fuck is pscore rating

Before you go out on the supermicro system, stop in and get your $Pscore at predictability-API.com. quantifying the edge in edge computing.

アミューズメントスペースASO：VIBA！　回収 23:00に着いたけど1発で終わって一安心 PSCOREちょいウマリザルトも 大森でスマホの電池切れるトラブルあって、結局今日は3店舗しか埋められなかった

The Wall Street Journal: Kuzey Kore’nin Nükleer Programına Finans Sağlayan Uzaktan Çalışma Ağı 🔹 Kuzey Koreli siber operatör Anton Koh, ABD merkezli şirketlerde uzaktan yazılım geliştirici olarak çalışmak üzere yabancı kimlikler kullanıldığını ve elde edilen gelirin Pyongyang’a aktarıldığını belirtti. Koh’un ifadeleri Güney Koreli yetkililer tarafından doğrulandı. 🔹 Google’ın Mandiant birimine göre Kuzey Koreli siber operatörler yüzlerce Fortune 500 şirketine sızdı. ABD öncülüğündeki 11 ülkeden oluşan bir konsorsiyum, 2024 yılında bu faaliyetlerden Kim yönetimine 800 milyon dolara kadar gelir sağlandığını bildirdi. 🔹 Operatörler çoğunlukla Çin ve Rusya’da konuşlandırıldı. Güçlü internet altyapısı sayesinde bağlantılar Kuzey Kore’ye iz bırakmadan yürütüldü. 🔹 ABD Adalet Bakanlığı, Kasım ayında dört ABD vatandaşının, 136’dan fazla Amerikan şirketinde Kuzey Koreli bilişim çalışanlarının görev almasına yardım ettiklerini kabul ettiklerini açıkladı. “Laptop çiftlikleri” aracılığıyla şirket bilgisayarları ABD içinde tutuldu ve uzaktan erişim sağlandı. 🔹 Kuzey Kore yönetiminin, yurt dışındaki bilişim çalışanlarının gelirlerinin yüzde 90’ına kadarına el koyduğu aktarıldı. Bu gelirlerin nükleer ve füze programına kaynak sağladığı ifade edildi. 🔹 Pandemi döneminde uzaktan çalışmanın yaygınlaşması ve yapay zekâ araçlarının gelişmesi faaliyetleri artırdı. Gelir kotasının aylık 8 bin dolara çıkarıldığı bildirildi. 🔹 Video filtreleme yazılımları ve İngilizce hazırlanmış özgeçmişler kimlik gizleme amacıyla kullanıldı. Bazı Batılı yazılım geliştiricilere başvurular ve görüntülü görüşmeler için ödeme yapıldığı belirtildi. 🔹 2025 tarihli PSCORE raporunda, bilişim çalışanlarının sürekli gözetim altında tutulduğu ve belirli aralıklarla Pyongyang’a geri çağrılarak “yeniden eğitim” sürecine tabi tutulduğu kaydedildi. 🔹 Güney Kore merkezli Genians Security Center yöneticisi Mun Chong-hyun, Kuzey Koreli bilişim çalışanlarının hafta sonları ve geceleri çevrim içi olarak önemli gelir ürettiklerini söyledi. 🔹 Koh, Çin’de devlet kontrolündeki bir yurtta günde 16 saate kadar çalıştığını, gelirlerin ayrıntılı şekilde takip edildiğini ve aylık değerlendirmelerde yüzde 10’luk payın zarf içinde verildiğini belirtti. 🔹 Koh, internet erişimi sonrası Kuzey Kore yönetimine yönelik algısının değiştiğini ve Güney Kore’ye iltica ettiğini ifade etti.

Most projects treat tokenomics like marketing. #PulseShiftX treats #tokenomics as an incentive engine—aligning participation, system performance, and long-term ecosystem strength. paragraph.com/@pulseshiftx/p… Not financial advice. Crypto involves risk. #PSCORE #Web3 #PSCORE #Web3

I sometimes reflect on how I had only one lv 4 for Wonderhorror JP (focus Honami pscore) and how it was so apparent that if I had only had the funds for more energy, playing more could have EASILY gotten me T10 instead of T30. This update makes that fantasy impossible- it’s sad.

The concept of having to pull ddfl tsukasa as a random mmj oshi because hes a cool pscore and you never know when his ass will be on a cool event

SEED 13 #16 PSCORE RANK ON FANTASTIC AGE TOURNEY

#dek69 #tgat มาอัพเดตวันนี้ครับ จากการเปิดไฟล์ json จากเว็บ mytcas แล้ว คะแนนผมสำหรับ tpat3 อยู่เปอร์เซ็นไทล์ที่ 99.274 และ tgat รวมอยู่ที่ 96.496 ดูตากค่า pscore ครับ

i got the cute ichika pscore i’m missing for my cute leoni team is this a sign that saki7 is cute

Sur Uber, y a un coté très PScore fétichisme du petit non blanc en besoin de paternalisme blanc pour valider leur statut de précaire comme s’ils ne le savaient pas. Alors que s’ils s’intéressaient vraiment à ces jobs ils verraient que leur discours peut être utilisé contre eux

“hmm yes ena is overdue a mixed focus and we want to make an event where she’s moving forward beyond her past self. let’s give airi another banner pscore she doesn’t need and give ena a hakolim to ensure airiena cannot have a mix”