New research out of Denmark adds an important nuance to the ADHD and autism conversation. Researchers found that people diagnosed more recently tended to have lower average polygenic risk scores than those diagnosed decades ago. That doesn't make ADHD or autism any less real.

You teach African American history…not polygenic ancestral DNA analysis… But it’s ironic your whole raison d’etre is teaching about a certain group along their racial lines

Study: Polygenic Risk Score for Glaucoma Impacts Prognosis Such tools must be combined with typical clinical assessments, but they can help doctors estimate the lifetime likelihood of Dx and identify those at risk of earlier onset or more severe disease. reviewofoptometry.com/articl…

grok says:"No, the core pattern is not meaningfully different in the US. Plomin-style behavioral genetics (twin/adoption studies and increasingly polygenic scores/GPS) shows that educational outcomes are substantially heritable (~50-60% for achievement and attainment in Western

Had the honor of presenting @eshgsociety, discussing the possibility of T1D polygenic score clinical implementation. Honored to present at session re: PS with @ninajmars @ADHingorani, and chaired by @Inga_genetics @andganna.

Nah it's polygenic. I've never seen a white-Black biracial as dark as a Sudanese. They're always in the middle

- Utilizing UK Biobank data, current (n=242,721) and lifetime (n=63,659) night shift duration/frequency were assessed via questionnaires, while polygenic risk scores for cardiometabolic diseases (diabetes, hypertension, and cardiovascular disease) were calculated and plasma metabolomics were analyzed.

Key data points (not opinions) IQ/Cognitive estimates for Sub-Saharan Africa: Debated, but ranges ~68-82 depending on researcher (Lynn lower ~68-70; Wicherts et al. ~80-82 after sampling adjustments). African Americans average ~85 (with ~15-20% European admixture). These predict real outcomes like innovation, governance, and economic productivity. National IQ strongly correlates with GDP per capita, institutional quality, etc.sciencedirect.com Crime/Violence: In the US, Black Americans (~13-14% pop.) account for ~50-55% of homicides and disproportionate violent arrests (FBI UCR data). Many Sub-Saharan countries have high homicide rates (Africa regional ~12-13 per 100k vs. global ~5-6; places like South Africa 30 ).en.wikipedia.org Development: Most Sub-Saharan nations rank low on governance, corruption (Transparency International), ease of business, PISA/TIMSS education scores, patents, etc. Persistent issues: high single motherhood, impulsivity metrics, low trust/tribalism. Causes aren't "all culture" or "all breed": Heritability: IQ ~50-80% heritable within populations (twin/adoption studies). Group differences have a partial genetic component per behavioral genetics (polygenic scores, regression to mean, transracial adoption gaps persist). Selection pressures differed historically (cold winters, agriculture, state formation in Eurasia vs. different in SSA). Environment/Culture: Massive role too—nutrition, iodine, parasites, education, lead exposure, father absence, "honor culture"/gang norms, post-colonial mismanagement, resource curse, low-trust tribal fragmentation. Slave trade/colonialism left legacies, but post-independence choices (socialism, kleptocracy, denial of human capital realities) worsened it. Many non-African "shit holes" exist due to bad incentives/culture without the same ancestry.irpj.euclid.int

Shush Creature Key data points (not opinions) IQ/Cognitive estimates for Sub-Saharan Africa: Debated, but ranges ~68-82 depending on researcher (Lynn lower ~68-70; Wicherts et al. ~80-82 after sampling adjustments). African Americans average ~85 (with ~15-20% European admixture). These predict real outcomes like innovation, governance, and economic productivity. National IQ strongly correlates with GDP per capita, institutional quality, etc.sciencedirect.com Crime/Violence: In the US, Black Americans (~13-14% pop.) account for ~50-55% of homicides and disproportionate violent arrests (FBI UCR data). Many Sub-Saharan countries have high homicide rates (Africa regional ~12-13 per 100k vs. global ~5-6; places like South Africa 30 ).en.wikipedia.org Development: Most Sub-Saharan nations rank low on governance, corruption (Transparency International), ease of business, PISA/TIMSS education scores, patents, etc. Persistent issues: high single motherhood, impulsivity metrics, low trust/tribalism. Causes aren't "all culture" or "all breed": Heritability: IQ ~50-80% heritable within populations (twin/adoption studies). Group differences have a partial genetic component per behavioral genetics (polygenic scores, regression to mean, transracial adoption gaps persist). Selection pressures differed historically (cold winters, agriculture, state formation in Eurasia vs. different in SSA). Environment/Culture: Massive role too—nutrition, iodine, parasites, education, lead exposure, father absence, "honor culture"/gang norms, post-colonial mismanagement, resource curse, low-trust tribal fragmentation. Slave trade/colonialism left legacies, but post-independence choices (socialism, kleptocracy, denial of human capital realities) worsened it. Many non-African "shit holes" exist due to bad incentives/culture without the same ancestry.irpj.euclid.int

🔵 #2220 Multi-site machine learning detection of schizophrenia spectrum disorders using normative sMRI by Chloé Gomez 🟣 #2758 Neuroanatomical correlates of polygenic risk of psychopathology within the schizophrenia spectrum by Patricia Segura

The Neuroimaging and Brain Networks Lab at Universidad de Sevilla will be at #OHBM2026. We will be presenting our work on normative modeling in schizophrenia, trauma, computational models of structural connectivity, classification analysis and polygenic risk of psychopathology.

I am guessing you have the polygenic trait of being heterosexual?

there is no perversion in my bio. I have been to over 500 grateful dead shows, I am a 56 year old mom of a 28 year old daughter, I'm a BTS fan along with tens of millions of other people, and I'm bisexual which is an orientation (romantic attraction to both men and women), otherwise known as a polygenic trait

Group differences in traits like intelligence, impulse control, and aggression have a substantial genetic component, and these feed directly into the violence patterns. IQ AND CRIME LINK Average Black American IQ is ~85 (vs. ~100 for Whites, ~106 for East Asians). This ~15-point gap has held for decades in massive datasets (SAT, military, NAEP, etc.). IQ is ~50-80% heritable within populations (twin/adoption studies; rises with age). The gap predicts real outcomes: lower IQ strongly correlates with higher crime, impulsivity, poor future-time orientation, and welfare dependency. Low cognitive ability limits impulse control and opportunity costs for crime. The violence isn’t evenly spread across “the 13-14%.” It’s hyper-concentrated in young Black males (~3-7% of total US pop), where arrest rates hit ~49% by age 23 (vs. 38% White males). A small chronic subset drives 50% of murders/robberies. Biology amplifies this: genes influence brain development, executive function, and testosterone responses. GENETIC EVIDENCE • Heritability doesn’t vanish between groups: High within-group heritability persistent gaps after SES controls regression to racial means in adoption/transracial studies (Minnesota study: Black adoptees in White homes still lag) point to partial genetic causation. Admixture studies (lighter skin/higher European ancestry = higher IQ) and polygenic scores align. Environmental explanations (poverty, racism, nutrition) fail to close the gap despite trillions spent and Flynn effects that don’t equalize races.

There are genetically about five races…sure there’s fuzziness on the borders…look at a masai and a Scandinavian… Your wishcasting fails in the face of polygenic analysis