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Replying to @Novichok5 @DakdaR22
You might want to check the actual rankings. Russia is far more corrupted than Ukraine. And even despite the ongoing war, Ukrainians are among the best improvers in the world!
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Scientists Concerned Latest Gene Editing of Human Embryos Could "Open the Floodgates" | Victor Tangermann, Futurism Editing the genes of a human embryo remains highly controversial, particularly after Chinese scientist He Jiankui shocked the world eight years ago by doing just that using the popular gene-editing technique CRISPR — and then allowing the embryos to be carried to term and born. Proponents say the tech could allow us to treat diseases in powerful new ways, while critics liken it to eugenics, arguing it could set a dangerous precedent by allowing parents to select certain desirable traits. It should therefore come to no surprise that the most recent attempt to edit human zygotes, embryos at their earliest single-cell stage, has once again fueled controversy. As detailed in a yet-to-be-peer-reviewed paper, a team led by Columbia University geneticist Dieter Egli used a technique called base editing, essentially editing a single strand of DNA, to edit two genomic sites. The goal wasn’t to establish promising new therapeutic or medical treatments, as the scientists noted in their paper. Instead, they attempted to demonstrate that base editing was a viable way of editing sequences of DNA in embryos without risking the damage earlier attempts involving CRISPR have caused. But as Scientific American reports, the latest research could lay the groundwork for more controversial work, despite the embryos not being carried to term, with pioneering genome‑editing researcher and Alexis Komor, who helped develop CRISPR, telling the publication that the “cat’s out of the bag.” Komor argued that without any strict regulatory oversight in the US, Egli and his colleagues may have broken an existing “gentleman’s agreement,” in the kind of research that “kind of opens the floodgates.” The geneticist called the latest study a “gateway to embryo editing to do enhancements,” highlighting how controversial the field remains. The research is also being supported by Nucleus Genomics, a company that screens IVF embryos for genetic disorders, which has already been steeped in controversy over its claims. Simply put, base editing makes tiny incisions in a single strand of DNA instead of removing entire segments, as is the case with CRISPR. Early experiments have already proved promising. Last year, a 9.5-month-old baby was cured of a rare genetic disorder thanks to a cutting-edge gene therapy involving base editing. Egli and his colleagues targeted two genomic sites that correspond to cholesterol management and hemoglobin production-related genes for their research, “because they are well studied in the context of somatic gene editing, rather than based on therapeutic promise in the germline,” according to the paper. But the results left something to be desired. For one, many of the edited embryos featured the same type of cells that differed genetically from each other, a phenomenon called mosaicism, which can lead to medical problems if the zygotes were to develop into embryos and eventually babies, as the New York Times points out. “It is possible that some of the potentially harmful effects would not be evident until after birth,” Wake Forest University bioethicist Ana Iltis, who was not involved in the research, told the NYT. The researchers behind the latest study, however, remain hopeful, explaining that plenty of work remains until the tech could be used to cure or head off diseases. “There’s still work to do before getting to that point, but this research gets us closer,” coauthor and Nucleus Genomics chief clinical officer Nathan Treff told the NYT. Others put it far less favorably. “What they are really doing is providing the ‘baby improvers’ with a how-to manual for forays beyond the ethical pale,” University of California, Berkeley, geneticist Fyodor Urnov, who was not involved, told the newspaper. futurism.com/health-medicine…
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Replying to @EYakoby
The two Karens will be ignored or just “liquidated” outright; the two guys and young woman will be sex slaves by the “diversity improvers”
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Medford I will be doing a show at H20 Bar and Grill. With local stand ups and Medford Improvers. It will be at 8 pm after Love Island watch party. This Tuesday.
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Fresh analysis from Ripon: Vega's Virtue and That's Enough led the last race, signaling strong form ahead. Easterby-trained filly looks poised to repeat, with Talking In Kode and Avispado as potential improvers. Read the full breakdown and insights. JuiceStorm.com/123
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Antik Basu retweeted
Joey Yarbrough falls but improvers her score with 75.85. #WSTour | #WorldCupRome
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#Khalifa Bin #Salman #Port has been ranked 19th globally in the latest Container Port Performance Index (CPPI), placing it among the world’s top-performing ports. The port has also been recognised as one of the top five global improvers for efficiency over the reporting period
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Achieve better rise, texture and baking consistency with premium leavening solutions. From baking powders to specialised bakery improvers, we supply reliable ingredients for cakes, biscuits, breads and more. #LeaveningAgents #BakingIngredients #BakerySolutions
Today’s EW Lucky up on @OLBG …..the quiet before the storm of Royal Ascot and with the side hustle of the World Cup keeping us busy with the form study, these are potential improvers & edge of the cliff nags! Should go well though. 🙏 Good luck all.
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The Rislone High Mileage Engine Repair is a powerful 2‑in‑1 additive designed to restore performance in older engines with over 75,000 miles (120,000 km). Its advanced formula combines viscosity improvers, anti‑wear agents, and seal conditioners. #Rislone #CarCare #HighMileage
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Then to @CaerphillyLTC for a short night's coaching due to the rain. Red Girls had a lot of fun and did well on returns, while lots of Green Boys missing but good work on their serves before some fun games. Cancelled both Womens and Men's Improvers as the courts were too slippery
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Heno yn #CTC // Tonight at #CTC: 🔴Junior Red Girls Only Coaching at 4pm 🟢Junior Green Boys Only Coaching at 5pm 🚻Adult Social Night from 6pm 🚺Women’s Improvers at 6pm 🚹Men’s Improvers at 7pm ℹ️👇 caerphillytennis.co.uk/
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Multigrade motor oils took off in the 1950s, using VI improvers so one oil could act like 10W in winter and 30 in summer. That idea powers today’s light, efficient grades. Try MOTOR OIL XT 5W-30: voiteluoljyt.fi/product/5w30….
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1 Jay & the GBD overplayed the role of natural & herd immunity. That confused US messaging. To be effective improvers of a pandemic response, one must know how pandemics work. The GBD did not have that expertise. Japan & Christian German Drosten knew how to address COVID.
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Just love dancing a Rondè in a Rumba💗Advanced routine coming along nicely. Our Beginners looked much more at ease as they did their Cha Cha👏🏻 and then we got everyone in a spin for the Improvers Plus, the Fleckerl will make sense…eventually🤭
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Replying to @kellard_
Thought it was interesting Haggas is willing to blow 104 with Yabher. They could be the two improvers Could’ve went straight to the John Smiths and gone off a lot shorter than he is for this, single figures maybe
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New Podcast He Was Banned 7 Times for Saying This About Black America | PBD Podcast #816 🤯 Hierarchy in Black communities: self-improvers vs. chaos enablers fueling "black fatigue." Personal responsibility beats excuses. Thoughts? #BlackAmerica Link in bio.
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North Melbourne v West Coast Eagles Battle of the improvers! North look to bounce back from a horror show as they face a much more competitive Eagles in Perth. #aflnortheagles
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racebuzz.com/newbury-racecar… 🏇 Newbury Racecourse hosts a competitive seven-race Flat card this Thursday, 11 June, featuring £100,000 in prize money and a strong mix of juveniles, improvers and experienced handicappers. Feature Ardonagh Group Handicap headlines the action at 3:30pm. @NewburyRacing #Newbury #HorseRacing #Racebuzz
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