Many Dottore mains blocked me before preload 6.6 after saying this, but I'll say it again. No, Dottore won't return and won't be playable. He's still portrayed as a monster, and all the characters hate him. I'm glad I left Genshin
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Dr. A. Murshid الدكتور/ عبدالإله عبدالرحمن مرشد retweeted
💧 Fluid Management in Heart Failure and Cardiogenic Shock
Preload vs Congestion
This chapter explains that in acute and chronic heart failure, the challenge is not simply “giving or withholding fluids” but balancing preload to support cardiac output against the risk of venous congestion and pulmonary edema. Conventional preload markers (CVP, PAOP) are often misleading in dilated, stiff or ischemic ventricles, so the authors emphasize integrated assessment using echo, blood pressure, urine output and clinical signs of congestion.
Cardiogenic Shock Strategy
In cardiogenic shock, small, carefully tested fluid challenges may be justified early, but ongoing hypotension is usually better addressed with inotropes, vasopressors and mechanical support rather than repetitive fluid boluses. The chapter highlights how positive fluid balance worsens outcomes in decompensated heart failure and advocates early decongestive therapy and, when needed, ultrafiltration as part of a broader deresuscitation plan.
📘 Full chapter in Rational Use of Intravenous Fluids in Critically Ill Patients:
👉 link.springer.com/book/10.10…
🔵 Discussed in depth at IFAD 2026 in Antwerp.
👉Registration: fluidacademy.org/ifad-2026-r…#HeartFailure#CardiogenicShock#FluidManagement#VEXUS#ICU
"I want it, and I want it paid for now", along with bonus goodies, and preload. Bad internet means preload makes me able to play the game at roughly the actual launch time.
There’s not real merit in doing it months in advance. I’ll preorder perhaps a couple of days before launch so I can preload it. I still get all the preorder bonuses too.
It's rare for me to pre-order, but if I do pre-order a PC game, it's simply so I can preload it. That way, I don't have to download 100GB when it releases.
GTA 6 preorders start June 25. Finally a real date to circle, but I’m still waiting on store pages before taking any price, edition, bonus, or preload details seriously.
That's a possibility, but retail copies will already be in the wild by then anyway, so people could already look through the disc. With a 100GB game I think they'll need to allow preload or some people will spend a full day downloading and installing it.
I predict servers to crash just from people preordering, no words for what will happen when the preload kicks of. Russian hackers might envy the effect it will have on the internet.