@ADJomics profile picture
Andrew Johnson @ADJomics

Framingham Heart Study NHLBI PI; research on Platelets in CVD; bleeding; using population approaches: genetics, epidemiology, RNA biology, bioinformatics

Joined April 2016
  • Tweets 155
  • Following 545
  • Followers 311
12 Photos and videos
Available open access at Platelets, our recent review on 60 years of research into ancestry differences in platelets: tandfonline.com/doi/full/10.…

Sixty years of research into ancestry differences in platelet function

Studies investigating the role of differential platelet function across various ancestry groups have been ongoing since at least the middle twentieth century. Consistently identified trends include...

tandfonline.com
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Now online in Blood, the largest genetic study to date of Heavy Menstrual Bleeding, reveals 36 Risk Loci. Most loci are not related to coagulation/hemostasis and instead other biological processes: ashpublications.org/blood/ar…

Genome-wide meta-analysis of heavy menstrual bleeding reveals 36 risk loci

Key PointsHMB shares a significant part of its genetic architecture with other disorders of the female genital tract.F5-Leiden was the only common coagulat

ashpublications.org
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There is a postdoc opening in March 2025 in my NIH Lab. Position can be located in either Boston/Framingham or D.C. area (Bethesda/NIH). Info an applying is here: training.nih.gov/jobs/pdr-04…
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Just opened Bluesky. You can also find me there ADJomics.bsky.social
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NIH Stadtman Tenure Track Faculty search is Open! Deadline Sep 30th. More information here: irp.nih.gov/careers/faculty-…
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Andrew Johnson retweeted
RPTH
@RPTHjournal
1 Sep 2024
Cool new science couples flow cytometry with machine learning to identify activated platelet subtypes! @ammmiiiii @nicola_dark1 @harri_allan @Plateletpaul @proftimwarner @ELShematology ➡️rpthjournal.org/article/S247…
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Following our discovery in humans for a role of GRK5 in platelets (cell.com/ajhg/fulltext/S0002…), glad to report platelet-specific knockout of Grk5 also modifies thrombin activation and thrombosis: rpthjournal.org/article/S247…

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease...

Dual antiplatelet therapy reduces ischemic events in cardiovascular disease, but it increases bleeding risk. Thrombin receptors PAR1 and PAR4 are drug targets, but the role of thrombin in platelet...

cell.com
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Cardiorespiratory Fitness Is Associated with Decreased Platelet Reactivity - PubMed (nih.gov) now online. Exercise regimens might be a dose to reduce thrombotic platelets. #ISTH2024
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Our new article on factors influencing Platelet assays (e.g., blood draw time, time to test, age, sex, medications, technician, seasonality) and inter-assay correlation in >3,400 people is now online: sciencedirect.com/science/ar… @RPTHjournal @isth

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Our new article in Platelets suggests associations between blood vessel diameter variation, subclinical vessel calcification and platelet function tandfonline.com/doi/full/10.…
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Andrew Johnson retweeted
ISTH
@isth
28 Aug 2023
ISTH Reach-the-World Fellowships offer emerging clinicians and researchers a global study opportunity. Read about the latest recipients here and plan to submit your application later this year: isth.org/news/650137/ISTH-Re…
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There is a postdoc position currently available in my group focused on bioinformatics/platelet genomics. NIH payscale with no prior postdoc experience is around $65-80K/year depending on specific expertise. Please contact me for more details.
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NIH Intramural Tenure Track PI applications (Stadtman Search) now open for all Institutes. Applications due Sep 30: irp.nih.gov/careers/trans-ni…
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Reminder: SSC Co-Chair interest/applications are due July 31. Info here: isth.org/news/641679/Apply-n… and apply here: survey.alchemer.com/s3/45011…
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Our new study out on Alcohol Platelet reactivity in 3,427 people. Alcohol associated with lower Platelet reactivity; generally stronger effects in women. Aspirin intake >>> Alcohol. No support for a Red wine-reduced Platelet reactivity hypothesis here: academic.oup.com/ije/advance…

Alcohol intake including wine drinking is associated with decreased platelet reactivity in a large...

AbstractBackground. Alcohol consumption is linked to decreased platelet function. Whether this link is dependent on sex or type of beverage remains unclear

academic.oup.com
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For an up-to-date view and review on platelet RNA-seq studies, check "Sources of variability in the human platelet transcriptome" recently in press sciencedirect.com/science/ar… @Florian_Th
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Andrew Johnson retweeted
Tregouet David-Alexandre@TregouetBPH
25 Jun 2023
Replying to @GaelleMunsch
@GaelleMunsch presenting the latest #GWAS results on #VTE recurrence #ISTH2023 . International collaborative work incl @ADjomics @INNOVTE1 @RodgerMarc @morange_pierre @FCouturaud @JF2leuze.... Hopes and clues for better prevention & patients treatment
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The ISTH GenOMICS SSC is expanding its mission and focus to include not only Genetics but multi-OMICS topics (Transcriptomics, Proteomics, etc.) We are seeking Co-Chairs in all OMICS domains. Please apply by July 31 @ ISTH SSC website #ISTH2023
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Announcing additional ISTH SSC Co-Chair positions now for Early Career or Reach-the-World individuals. Apply by July 31 @ ISTH SSC website #ISTH2023
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Andrew Johnson retweeted
Kathleen Freson@KathleenFreson
12 Jun 2023
Different open positions for the SSC in Genomics. @ADJomics Interested in Omics? please apply now !!! 👇
ISTH
@isth
1 Jun 2023
Now open! Apply to serve and an SSC Subcommittee Co-Chair at isth.org/news/641679/Apply-n…
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