Investigative Ophthalmology & Visual Science (IOVS) is an open access, peer-reviewed online journal of the Association for Research in Vision in Ophthalmology.

Joined August 2013
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12 Jan 2023
With IOVS and TVST partially overlapping scope, we have developed guidance for authors to help them determine which journal would be the best fit for their manuscript. Take a look here: iovs.arvojournals.org/ss/for…

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Srinivas R. Sadda et al. from Doheny Eye Institute longitudinally evaluate whether residual RPE area loss in choroideremia (CHM) demonstrates directional asymmetry over 12 months. doi.org/10.1167/iovs.67.6.23
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Elizabeth A. Berger et al. from Wayne State University School of Medicine evaluate whether adjunctive Tβ4 supports nerve regeneration and restores visual function after corneal infection. doi.org/10.1167/iovs.67.6.22
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Reddikumar Maddipatla et al. from UC Davis Eye Center investigate subretinal aspects of the optoretinographic response. doi.org/10.1167/iovs.67.6.21
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Sachi Kojima et al. from Kumamoto University investigate the effects of the Rho kinase inhibitor ripasudil on immune cells activated by monocyte chemoattractant protein-1 (MCP-1), a known risk factor for glaucoma filtering surgery failure. doi.org/10.1167/iovs.67.6.20
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Yong Sook Goo, Eoi Jong Seo et al. from Chungbuk National University College of Medicine find that retinal detachment is associated with enhanced correlated firing and oscillatory activity. doi.org/10.1167/iovs.67.6.19
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Emily Davis, Abdullah Khan & Issam Aldiri from the University of Pittsburgh School of Medicine find that Ezh2 control of bivalent genes fine-tunes developmental competence during retinogenesis. doi.org/10.1167/iovs.67.6.18
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Ruibo Yang, Shaozhen Zhao et al. from Tianjin Medical University Eye Hospital investigate the role of sex hormone imbalance in keratoconus (KC) pathogenesis and its effects on corneal collagen metabolism and biomechanics. doi.org/10.1167/iovs.67.6.17
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Lijun Shen et al. from Zhejiang Provincial People’s Hospital investigate candidate regulatory proteins associated with the pathogenesis of pterygium and to explore their potential biological roles. doi.org/10.1167/iovs.67.6.16
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Baihua Chen et al. from The Second Xiangya Hospital of Central South University find that chrysin attenuates dry eye progression by suppressing NOX2-dependent ferroptosis and STING/NLRP3-mediated inflammatory responses. doi.org/10.1167/iovs.67.6.15
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Hua Gao, Shengqian Dou et al. from the Eye Institute of Shandong First Medical University find that NEDD8 promotes the progression and inflammation of keratoconus by increasing the expression of YAP1. doi.org/10.1167/iovs.67.6.14
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Hosein Hoseini-Yazdi et al. from Queensland University of Technology examine changes in retinal perfusion density (PD) following short-term exposure to optically induced myopic defocus and achromatic digitally simulated myopic blur. doi.org/10.1167/iovs.67.6.13
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Vallabh E. Das et al. from the University of Houston describe the dose-response characteristics of retinal inactivation due to intravitreal injections of tetrodotoxin in nonhuman primates. doi.org/10.1167/iovs.67.6.12
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Robert J. Zawadzki, Paul A. Sieving et al. from UC Davis find that modulation of systemic osmolarity alters retinal thickness and schisis cavities without blood retinal barrier disruption in Rs1 knockout mice. doi.org/10.1167/iovs.67.6.11
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Jinling Fu et al. from The Second Hospital of Jilin University find that diosgenin attenuates photoreceptor degeneration in an N-Methyl-N-Nitrosourea–induced mouse model of retinal degeneration. doi.org/10.1167/iovs.67.6.10
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Anand Swaroop et al. from the National Eye Institute @NatEyeInstitute find that stress responsive bZIP transcription factors ATF4 and BACH1 cooperate with MAF-family bZIP protein NRL to fine-tune rod photoreceptor gene expression. doi.org/10.1167/iovs.67.6.9
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Chien-Chih Chou from the National Yang Ming Chiao Tung University investigate RANKL inhibition and the risk of ocular hypertension and primary open-angle glaucoma. doi.org/10.1167/iovs.67.6.8
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Guangying Zheng et al. from the First Affiliated Hospital of Zhengzhou University investigate the role of lncRNA GAS5 and GADD45a in H₂O₂-induced oxidative stress and mitochondrial dysfunction in human lens epithelial cells. doi.org/10.1167/iovs.67.6.7
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Zijiang J. He et al. from the University of Louisville investigate absolute distance discrimination in the intermediate distance mediated by angular declination/elevation and binocular disparity cues. doi.org/10.1167/iovs.67.6.6
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Francine Behar-Cohen et al. from the University of Paris Cité find that steroidome dysregulation and complement C4 copy number variation in men with central serous chorioretinopathy. doi.org/10.1167/iovs.67.6.5
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Peizeng Yang et al. from The First Affiliated Hospital of Chongqing Medical University find that adalimumab reprograms M1 macrophages to attenuate Th1/Th17 responses in Behçet's uveitis and Vogt–Koyanagi–Harada syndrome. doi.org/10.1167/iovs.67.6.4
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