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Alberto Macho @AlbertoPMacho

Scientist studying Plant-Pathogen Interactions. Scuba diving. Hiking. Football. Photography. @albertopmacho.bsky.social

Joined November 2010
  • Tweets 843
  • Following 586
  • Followers 1,897
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Alberto Macho@AlbertoPMacho
29 May 2025
Slowly migrating to Bluesky @albertopmacho.bsky.social
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Alberto Macho retweeted
Eloísa del Pino@delPinoE
Apr 16
🤝 @CSIC firma un acuerdo con la Academia de Ciencias China La negociación comenzó en 2025, con el Presidente de CAS, Jianguo Hou en Madrid Ha dado lugar al intercambio de 4 grupos de investigación en agricultura y medioambiente @IRNAS_CSIC @ICMCSIC @CBGP_Madrid @CidEinvestiga
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Alberto Macho retweeted
Gang Yu@GangYuPlant
Apr 17
Replying to @AlbertoPMacho
@AlbertoPMacho and I summarize advances in understanding how T3Es modulate cellular processes beyond immune signaling for colonization in COPB. Sabotage behind enemy lines: Bacterial hijacking of plant cellular fun... sciencedirect.com/science/ar…
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Alberto Macho retweeted
Eloísa del Pino@delPinoE
Apr 13
Para finalizar el día, hemos mantenido una interesantísima reunión en 1 de los 120 institutos de la Chinese Academy of Science: Center for Excellence in Molecular Plant Sciences Sus investigador@s trabajan con 4 institutos @CSIC. Vamos reforzar el vínculo
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Alberto Macho retweeted
Eloísa del Pino@delPinoE
Mar 30
El @CSIC activa su programa de movilidad con la Chinese Academy of Sciences, su homóloga, q se firmó hace unos meses Iniciativa importante para estrechar la colaboración en proyectos científicos y publicaciones de 1er nivel. España aún firma poca ciencia con China, Heitor Report
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Our latest paper is now online at New Phytologist!   Phosphorylation-dependent association of a bacterial effector with plant 14-3-3 proteins enhances effector stability and bacterial virulence   doi.org/10.1111/nph.70510 @NewPhytol

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These phosphorylation sites seem to be important for RipBM contribution to virulence in tomato, reflecting an effector strategy to promote its own stability and contribute to bacterial virulence
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Together with our previous report earlier this year (Yu et al, PLoS Pathogens, 2025), this work suggests that hijacking plant kinases is an important strategy for bacterial effectors to promote their own phosphorylation and stability in plant cells doi.org/10.1371/journal.ppat…

A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation

Author summary Most bacterial plant pathogens inject effector proteins inside host cells to suppress immune responses and manipulate other plant functions in order to cause disease. Even though these...

journals.plos.org
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Alberto Macho retweeted
Jose Rufián@jrufian86
2 Sep 2025
Our new paper is out in New Phytologist! We describe how the Ralstonia solanacearum effector RipAV suppresses plant immunity by directly interfering with key defense regulators. 🧵👇 nph.onlinelibrary.wiley.com/…

The Ralstonia solanacearum effector RipAV targets plant U‐box proteins and induces proteasomal‐de...

Plants have developed a complex immune system to detect and respond to invading pathogens. A critical aspect of this defense relies on regulatory mechanisms that control the activation of immune...

nph.onlinelibrary.wiley.com
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Alberto Macho retweeted
Jose Rufián@jrufian86
30 Jul 2025
🎉 Thrilled to announce that CoBEPP — Using conserved bacterial effectors to probe plant-pathogen interactions — has been funded by @AgEInves & @cienciaGob! Grateful for the support to launch my first project at @IHSM_CSIC_UMA, exploring how pathogens affect plant biology! 🌱🔬
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Our latest article is now online! @PlantBiotechJ Expression of Arabidopsis FLS2 in N. benthamiana confers responsiveness to Ralstonia flg22 and activation of anti-bacterial immunity doi.org/10.1111/pbi.70255 By Meng Li, Yujiao Chen, and Yali Wei (@albertopmacho.bsky.social)

Heterologous expression of Arabidopsis FLS2 in Nicotiana benthamiana confers responsiveness to...

The association between Arabidopsis FLS2 and BAK1/SERK3 triggered by bacterial flagellin is the best-studied example of plant PRR receptor/co-receptor complex. Although most plants are able to...

onlinelibrary.wiley.com
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Long story short, it seems that AtFLS2, when expressed in N. benthamiana, associates with NbSERKs and mediate a “partial” complex activation that leads to some downstream responses (MAPK, gene expression), but not others (ROS). Eventually, this enhances disease resistance
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Hopefully, the information that heterologous PRR expression can confer novel PAMP recognition could provide new information for the design of synthetic immune receptors with expanded recognition of polymorphic pathogen elicitors
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Alberto Macho retweeted
CSIC
@CSIC
16 Jun 2025
📜 El #CSIC firma dos memorándums de entendimiento con la @CAS__Science  🏛️ Ambas instituciones promoverán la cooperación científica centrada en proyectos sobre agricultura sostenible, alimentación y cambio climático 👉 tiny.cc/s5km001
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Alberto Macho retweeted
Eloísa del Pino@delPinoE
13 Jun 2025
🇨🇳🇪🇸La ciencia es un lenguaje universal Hoy el @CSIC ha firmado un acuerdo de colaboración con el principal organismo científico chino, CAS, y la activación inmediata de un programa de intercambio de investigador@s entre las 2 instituciones Gracias al Presidente Hou Jianguo!
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Alberto Macho retweeted
IHSM La Mayora@IHSM_CSIC_UMA
3 Apr 2025
📋 New paper from our researchers Carmen Beuzón, Javier Ruiz-Albert, Nieves López-Pagán and José Rufián! Published at @NatureMicrobiol More information here! ⬇️ nature.com/articles/s41564-0… @InfoUMA @CSIC

Pseudomonas syringae subpopulations cooperate by coordinating flagellar and type III secretion...

Nature Microbiology - Single-cell gene expression analysis reveals phenotypic heterogeneity to enable bacterial specialization over the course of plant colonization.

nature.com
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