🏆 Congratulations to @ChadTangMD et al. on receiving our April IMPACT Award!
This month's winning paper stands out for its contribution to understanding how we can better predict outcomes for patients with Oligometastatic Clear-cell Renal Cell Carcinoma — an important step forward for personalised care.
Well deserved. 👏
#IMPACTAward#EuropeanUrology#renalcellcarcinoma#Oncology#Urology
@GiulioFrancoli1 at #estro2026 presents early results of the randomized PERSIAN trial. Results are early showing excellent PSA response in both arms (mdt slightly better) but definitely more to come.
1/ Tremendous thanks to the patients, coauthors and all who made the EXTEND trial possible. The primary aggregated analysis is now available online @JCO_ASCO with ctDNA correlatives presented synchronously at @ESTRO_RT#ESTRO26
6/ EXTEND supports MDT SOC as a strategy in oligometastasis and opens the door to multiple promising new directions to further improve outcomes with MDT in oligometastasis,. such as ctDNA guided care meriting future RCTs
@piet_ost excellent presentation on the DART trial randomizing mdt and mdt 6 mo darolutamide in oligomet prostate cancer with temporary delay of progression only while the hormone therapy was being administere. #estro26
The K-COMPASS study by @ChadTangMD shows how ctDNA and KIM-1 are prognostic and can be used to estimate treatment-free survival in patients with oligometastatic RCC #ASCOGU26@PavlosMsaouel
At #GU26 a tremendous overview of optimal trial design by @PavlosMsaouel. Pavlos has repeatedly shown that even in very rare cancers, optimally designed studies can rapidly led to practice changing findings. A visionary in our field.
Extremely excited to share our latest article published @TheLancetOncol a few hours ago: authors.elsevier.com/a/1mYT6….
The WOLVERINE individual patient meta-analysis was an international collaboration and part of X-MET collaboration. Goal was to evaluate MDT in oligomet prostate ca.
The UromigosLive 2025 meeting presents #UromigosShorts videos on GU Oncology topics. The videos with the most views win a prize at #UromigosLive November 7-8th in Nashville, TN. Below, Dr. Chad Tang discusses: Metastasis-directed Therapy in RCC.
Does the addition of MDT to standard of care continuous ADT improve outcomes for oligomet prostate ca?
Happy to share the results of EXTEND evaluating this question alongside PI @ChadTangMD & many others
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Nonetheless EXTEND is a critical step forward for improving outcomes in oligomet prostate ca and supports the role of MDT with multiple ADT strategies.
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Many thanks to the outstanding study team/coordinators, collaborators & the pts and families who participated in the trial. My special gratitude for the mentorship of @ChadTangMD in this study.
Full text:
authors.elsevier.com/c/1lX0v…