Bäckhed Lab takes a translational research approach to investigate how the gut microbiota contributes to cardiometabolic disease.

Joined August 2020
38 Photos and videos
We have extended the deadline! Register to the #microbiota and health course by 6 August!
Registration is open for NDPIA's Microbiota and Health course held at @storabrannbo on Oct 7-11! In addition to the lectures, we will have two workshops this year that focus on retrieving, annotating and analysing metabarcoding data in R. Register today: ndpia.se/events/microbiota-a…
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Excited and grateful to be part of this @novonordiskfond sponsored initiative to investigate if the gut microbiome causes cardiometabolic disease in humans!
By adding bacteria to our gut, removing them, or changing what we eat, we could reduce our risk of developing diseases such as obesity, type 2 diabetes, and cardiovascular disease. A new research project, led by @foodDTUdk at @DTUtweet and funded by the Novo Nordisk Foundation, aims to find out more about this link, ultimately leading to new prevention or treatment options for people living with, or at risk of, cardiometabolic disease. novonordiskfonden.dk/en/news… #obesity #diabetes #cardiovasculardisease
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Bäckhed Lab retweeted
Extremely happy to share that our work on how specific #gutbacteria modulate #mucus function under low-fiber #diet is now out in @natcomms! #gutmicrobiota #glycotime #probiotics #fiber nature.com/articles/s41467-0…
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In collaboration with @DanielJDrucker we made the surprising observation 10 years ago that GLP-1R deficient mice dies. Further work led by @GreinerTU with support from @MucinBiology revealed involvement of #gobletcells.
More essential roles for GLP-1R in the mouse gut, here in the maintenance of colonic physiology and survival during energy deprivation in germ free mice @BackhedLab @MolMetab sciencedirect.com/science/ar…
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Ending the fall semester celebrating two excellent PhD defenses from Wilhelm Sjöland and Jamie Kraft @kraftyjamie . So proud of both of you - good luck with your future careers!
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Bäckhed Lab retweeted
18 Dec 2023
The second #TopGUTpaper from #Feb2023 is by Makki et al on “6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice” via bit.ly/482z7Ct Podcast: bit.ly/3ROotJJ @BackhedLab
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4 Aug 2023
Nature research paper: Synergy and oxygen adaptation for development of next-generation probiotics go.nature.com/3DENnDN

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Great work - happy to see it finally published. Essentially, "how to train your microbiota" 💪🦠 from @BackhedLab in @Nature
Here we report on co-isolation of #Faecalibacterium prausnitzii and a Desulfovibrio piger strain, which are abundant and prevalent in the human gut. D. piger increases the biomass and butyrate production of F. prausnitzii. nature.com/articles/s41586-0…
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⁦@YolsanzSanz⁩ provides a great overview of our paper just poulished in ⁦@Naturenature.com/articles/d41586-0…

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Following oxygen adaptation of F. prausnitzii, which allowed production of live bacteria products, we could in collaboration with @LorentzoM demonstrate that the combination is safe for human consumption that will allow further intervention studies.
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Thanks to all authors and especially first authors @mtanweerkhan2 and @ChiDwi_Tweets @SahlgrenskaAcad @sahlgrenska @KAWstiftelsen
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