Perplexed sceptic & genetic epidemiologist @mrc_ieu @MRC_BSU @BristolUniPsych. Tutor @LSHTM & @StEdmundsCam.

Joined November 2017
25 Photos and videos
Benji Woolf retweeted
Really important work (and delighted to help) using pulmonary hypertension as a disease exemplar. Applicable across all rare disease I expect.
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One of my students @StEdmundsCam has a really remarkable story of overcoming adversity to study @Cambridge_Uni. Sadly his scholarship can't fund the rest of his degree so he is trying crowdfunding. Any help would be really appreciated, thank you very much! gofundme.com/f/from-poverty-…
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Benji Woolf retweeted
New pre-print online: "Context-stratified Mendelian randomization: exploiting regional exposure variation to explore causal effect heterogeneity and non-linearity", arxiv.org/abs/2507.11088. We propose an alternative approach to assess non-linearity in Mendelian randomization.
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Benji Woolf retweeted
New paper published at AJE Advances: "The role of estimation in Mendelian randomization: should Mendelian randomization investigations provide estimates?" led by @BarWoolf and myself. Brief thread:
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21 Jun 2024
And the accepted m/s is now out in the AJE! academic.oup.com/aje/advance… Thank you to @htcronje @dpsg108 @stevesphd @LoukasZagkos @LarssonSC Summary can be found x.com/BarWoolf/status/166459…
20 Jun 2024
Had a lot of fun presenting our work (accepted this week at the AJE) on exposure miss-identification in MR, and how it results in directionally incorrect conclusions for studies of caffeine consumption at #mrconf24.
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20 Jun 2024
Had a lot of fun presenting our work (accepted this week at the AJE) on exposure miss-identification in MR, and how it results in directionally incorrect conclusions for studies of caffeine consumption at #mrconf24.
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Our new study erj.ersjournals.com/content/… with James Perry, Charles Hong @mark_toshner, @stevesphd, @dpsg108, Martin Wilkins, and Chris Rhodes failed to find evidence supporting the use of IL6R inhibitors on pulmonary arterial hypertension.

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Benji Woolf retweeted
New Mendelian Randomization from @LoukasZagkos @htcronje @BarWoolf @stevesphd @Yuan_AS @LarssonSC @jotzou @dpsg108 et al.: Long-term increases in circulating #caffeine may reduce bodyweight and the risk of osteoarthrosis and osteoarthritis. shorturl.at/blySV
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Benji Woolf retweeted
**Flash Talks Event** Benjamin Woolf @BarWoolf shares his research "Comparison of caffeine consumption behavior with plasma caffeine levels as exposure measures in drug-target Mendelian randomization studies" Vote for your favourite talk: meg-uk.org/flash-talks-2024
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Benji Woolf retweeted
New paper: "A frequentist test of proportional colocalization after selecting relevant genetic variants": arxiv.org/abs/2402.12171 led by Ash Patel. We introduce a new test for colocalization in a frequentist paradigm. Thread follows!
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25 Jan 2024
Really nice review by @htcronje and @stevesphd on the importance of sensible variant selection in MR
Our review "Incorporating biological and clinical insights into variant choice for Mendelian randomisation: examples and principles" written together with @htcronje and published at @eGastro_BMJ is now available at egastroenterology.bmj.com/co…. Brief thread:
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Benji Woolf retweeted
Thanks to Benji (@BarWoolf) and Dipender (@dpsg108) for leading this work, and for Skanda, Toinét (@htcronje), James (@jamesyrmsk), and the BMJ editors for their willingness to engage with both the science and the humour of the article. /END
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