@BenjaminSolomo2 profile picture
Benjamin Solomon @BenjaminSolomo2

Geneticist

Joined March 2012
  • Tweets 2,750
  • Following 730
  • Followers 1,900
573 Photos and videos
It’s #GivingTuesday! I’ve joined the movement; will you join me? All gifts to Geisel School of Medicine will be DOUBLED -- that means your support will go twice as far to help transform healthcare education and support future physicians. Give online at dartgo.org/gt-Geisel
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Benjamin Solomon retweeted
National Human Genome Research Institute@genome_gov
4 Apr 2023
NHGRI’s Clinical Director @BenjaminSolomo2 first fell in love with genetics and genomics in the 7th grade. In medical school, he admired geneticists who were determined to help diagnose patients.
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Benjamin Solomon retweeted
Florian Krammer
@florian_krammer
11 Dec 2022
Here, I said it and I am saying it again.
Florian Krammer
@florian_krammer
15 Jul 2020
That's leadership. Anthony Fauci is a national treasure.
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Benjamin Solomon retweeted
Fyodor Urnov@UrnovFyodor
9 Dec 2022
"Unless things change dramatically, the millions of people #CRISPR could save will never benefit from it. We must, and we can, build a world with #CRISPR for all." #healthjustice @igisci @nytimes nytimes.com/2022/12/09/opini…

Opinion | We Can Cure Disease by Editing a Person’s DNA. Why Aren’t We? (Published 2022)

Revolutionized medicine may be at hand, but barriers remain.

nytimes.com
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This was a very fun project to work on: I asked a number of colleagues to discuss their thoughts (and hopes) regarding the way the field of dysmorphology may evolve. @acedens @KrawitzPeter @shahida_moosa onlinelibrary.wiley.com/doi/…

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Also tagging @CedrikNT, who wrote a great section on “The Future of Dysmorphology: A Global Perspective”
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Benjamin Solomon retweeted
Eric Green@NHGRI_Director
9 Dec 2022
.@Genome_gov’s Cynthia Tifft runs a gene therapy clinical trial for children with GM1 gangliosidosis. Fewer than 5% of rare disorders have effective treatments, but after working with her young patient Jojo, Cynthia’s team has treated 10 more children with this condition.
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Q425 Out of 100 people with pathogenic variants in a certain gene, 50 develop heart disease; out of 100 people without pathogenic variants in that gene, 10 develop heart disease. What is the relative risk of heart disease in people with pathogenic variants in that gene?
12% 0.4
22% 0.5
2% 1
64% 5
172 votes • Final results
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Q425 answer: 5
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Super cool article by @genome_gov colleagues on the genetics of dog behavior (one fascinating thing they saw: "a sheepdog-associated enrichment for interrelated axon guidance functions") cell.com/cell/fulltext/S0092…

Domestic dog lineages reveal genetic drivers of behavioral diversification

A framework for understanding the relationships between canine breeds allows for the identification of genetic drivers of the behaviors that define them.

cell.com
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A good joke my son told me (he may have come up with this himself in bio class): What did chlorophyll call their imaginary friend? A pigment of their imagination. Here's a DALL-E 2 picture we made of "an oil painting of a fancy chloroplast in a suit"
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Benjamin Solomon retweeted
Anne Carpenter, PhD@DrAnneCarpenter
3 Dec 2022
What’s heavier: a protein or the mRNA that encodes it?
31% Protein
32% mRNA
12% Depends
25% Show results
28,978 votes • Final results
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Benjamin Solomon retweeted
National Human Genome Research Institute@genome_gov
2 Dec 2022
Uh oh, your Spotify Wrapped doesn’t look great. Let’s try to do better next year so our opossum stops getting angry. Learn more about the importance of diversity in genomic studies in our fact sheet: go.usa.gov/xtkAp
An image of Spotify Wrapped that features a photo of an opossum screaming into a microphone. The caption says "You spent 2,257 minutes enraging our NHGRI opossum for not including enough diversity in your genomic studies.

ALT An image of Spotify Wrapped that features a photo of an opossum screaming into a microphone. The caption says "You spent 2,257 minutes enraging our NHGRI opossum for not including enough diversity in your genomic studies.

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Q424 A female child with short stature is seen by her physician, who notices a heart murmur on examination. A chest x-ray is shown below (see next tweet). What initial test would likely be the most logical to order?
12% Acylcarnitine profile
75% Karyotype
8% Whole genome sequencing
6% Methylation testing
346 votes • Final results
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more replies
For those having a hard time, the red circle indicates an important area of the x-ray...
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Q424 Answer: Karyotype pubmed.ncbi.nlm.nih.gov/3803… pubmed.ncbi.nlm.nih.gov/1809… pubmed.ncbi.nlm.nih.gov/3121… pubmed.ncbi.nlm.nih.gov/3579…
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Benjamin Solomon retweeted
Prof Zornitza Stark@ZornitzaS
29 Nov 2022
🤔 are saliva or blood samples better for microarray? Our latest @ejhg_journal: we compare results from 270 children who had both: 20 extra diagnoses using saliva due to mosaic CNVs 🔍🧬 Congrats @TeamVCGS @DavidFr87880457 @wall_meaghan @GenomeSeb 👏 rdcu.be/c0FwO

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Q423 Which is the only amino acid specified by a single codon?
11% Leucine
17% Phenylalanine
60% Tryptophan
12% Valine
164 votes • Final results
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I hope everyone had plenty of tryptophan for Thanksgiving! As a bonus, can you name the only OTHER amino acid with a unique codon? Hint: if you get this right, you'll be off to a good start.
5% Arginine
9% Cysteine
84% Methionine
2% Tyrosine
86 votes • Final results
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Q423 (and bonus) answer: Tryptophan (bonus: Methionine) genome.gov/genetics-glossary pubmed.ncbi.nlm.nih.gov/3323… ncbi.nlm.nih.gov/books/NBK55…
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