Physician-Scientist, Writer ("Rethinking Hypothyroidism"), and Dean @utmb_jssom. #thyroid, #hypothyroidism, #ThyroidDisease, #EndoTwitter.

Joined January 2014
66 Photos and videos
Pinned Tweet
Treatment of Hypothyroidism that Contains T3 is Associated with Reduced Risk of Dementia and Mortality. Results from 1.26 million patients with hypothyroidism, 126 health organizations across 17 countries. academic.oup.com/jcem/articl…
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Massive goiter (left) versus a control thyroid (right)!! The goiter is due to inactivation of the thyroglobulin gene. It compensates for inefficient T4 production in dead thyrocytes, thereby keeping T4 levels normal. Kudos to the Arvan group!! pubmed.ncbi.nlm.nih.gov/4180…
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In Vegas for AACE2026 (@TheAACE). I am impressed with how much this group has grown since Paul Jellinger, Jeff Garber and others started it. Congratulations!!
Apr 24
Watch highlights from Day 2 of #AACE2026
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Antonio C Bianco retweeted
In episode #373 of The Drive, I sit down with Antonio Bianco, M.D., Ph.D. (@bianco_lab), a world-renowned physician-scientist and expert in thyroid physiology and metabolism. Antonio explores the complex biology of thyroid hormone production, conversion, and regulation. bit.ly/3K4LoiX
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Great work by @FedeSalasLucia !!!!!
Thyroid hormones are important for neurodevelopment during the first trimester of pregnancy. Here, @FedeSalasLucia @Bianco_Lab & team @UChicago model suboptimal thyroid hormone levels during the early stages of cerebral cortex development, revealing an unappreciated role for T4 in promoting early fetal cerebral cortex development: insight.jci.org/articles/vie…
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Preexisting hypothyroidism in 5,700 patients undergoing bariatric surgery increases the risks of short and long term adverse outcomes. Risks were higher in patients who underwent gastric bypass academic.oup.com/jcem/articl…
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We followed 105 patients before and after developing hypothyroidism (on LT4). Those patients with lower T3 were at risk for dyslipidemia (47.5% vs. 27.3%); even after adjusting for confounders (adjusted OR: 3.6). Monitoring T3 levels should be considered. endocrinepractice.org/articl…

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Antonio C Bianco retweeted
1 Jul 2025
🚨 New NIH Public Access Policy goes into effect TODAY! Research accepted for publication on July 1, 2025, must be publicly available as soon as it is published. This date was moved up from December 31, 2025, to ensure radical transparency regarding the research NIH supports. Read more from @NIHDirector_Jay ➡️ go.nih.gov/zQRDiuk
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Antonio C Bianco retweeted
Treatment of Hypothyroidism that Contains T3 is Associated with Reduced Risk of Dementia and Mortality. Results from 1.26 million patients with hypothyroidism, 126 health organizations across 17 countries. academic.oup.com/jcem/articl…
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Treatment of Hypothyroidism that Contains T3 is Associated with Reduced Risk of Dementia and Mortality. Results from 1.26 million patients with hypothyroidism, 126 health organizations across 17 countries. academic.oup.com/jcem/articl…
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This is the data showing increased mortality despite treatment with LT4. To be discussed tomorrow at @ITC2025 .
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Hundreds of surfers watching the sunrise in Copacabana, Rio.
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This is an impactful study that should reset the approach to the treatment of hypothyroidism. I will show details on Sunday, during the 17th International Thyroid Congress in Rio.
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Over a 20-year follow-up, patients receiving combination therapy (LT4 T3 or DTE) had a 27% lower risk of dementia and a 31% lower risk of mortality compared to those receiving LT4 alone. Adjusted Cox proportional hazard models confirmed the results.
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This is a remarkable testimony of a patient’s journey through hypothyroidism. All should read it and reflect on how providers approach patients with thyroid disease. Kudos to Mary Saunders!
15 May 2025
My article was published in Nature review! My struggle to get accurate diagnosis and effective treatment for hypothyroidism: nature.com/articles/s41574-0…
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Last Thursday I had the pleasure of speaking at Kuma Hospital in Kobe, Japan. Profs. Ito and Akamizu explained that they keep thyroidectomized patients on LT4 and a subnormal TSH to normalize T3 levels and minimize residual symptoms, with very positive results overall.
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Look at these new and exciting findings! Some areas of the brain (e.g., the cerebellum) in LT4-treated mice remain hypothyroid even after TSH levels have normalized. Could this contribute to the brain fog reported by many patients on LT4? pnas.org/doi/10.1073/pnas.24…

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