@BioVivaScience profile picture
BioViva USA Inc @BioVivaScience
Joined April 2016
  • Tweets 1,642
  • Following 28
  • Followers 3,648
373 Photos and videos
Healthy people show a brief FGF21 drop after stress, while those with mitochondrial disease show a delayed rise. FGF21 also reflects social and emotional factors, linking stress and metabolic health. pulse.ly/ptgxwa9xga

Feeling Stressed? A Hormone Called FGF21 May Be the Reason Why

A study reveals that the metabolic hormone FGF21 is also a stress hormone, connecting psychological stress to how the body uses energy. Stress, loneliness and poor social ties change FGF21 levels.

technologynetworks.com
1
4
655
Fasting triggers the body to shift from using glucose to burning fat and producing ketones, coordinated by hormones and liver signals like FGF21. Mice without liver-produced FGF21 still showed normal fasting metabolism, but they lost the usual increase in protein appetite
2
4
680
In C. elegans, the RNA that maintains chromosome ends doesn't have its own gene but is hidden inside another gene and "hitchhikes" there. This discovery may be common in animals and could inform future regenerative medicine research. pulse.ly/muyevbreel

Hitchhiking DNA in C. elegans Solves Telomerase Puzzle, with Regenerative Promise

Discovery of the long-elusive terc-1 in C. elegans provides fundamental insights into mechanisms of germline immortality and species survival.

genengnews.com
1
5
511
PAX3 and PAX7 guide the development of different neural cell types in the embryonic spinal cord. This activation occurs only in cells exposed to BMP signals. pulse.ly/binepahttp

Dual transcriptional activities of PAX3 and PAX7 spatially encode spinal cell fates through...

How do transcription factors, with pleotropic functions, generate organized cellular diversity in developing tissues? This study shows that PAX3 and PAX7 orchestrate spinal cord patterning by acting...

journals.plos.org
1
242
Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. pulse.ly/j4todlehsj

Scientists just made gene editing far more powerful

Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike tradit...

sciencedaily.com
4
317
"A neurologist at the University of Cambridge, used data from the massive UK Biobank resource and found a link between reduced glymphatic function and increased risk of dementia. pulse.ly/yuyisvtriz

Clogged Glymphatic System Linked to Dementia Risk | The Scientist

MRI scans from nearly 40,000 people revealed biomarkers linked to defective toxin clearance in the brain predicted the susceptibility to dementia later in life.

the-scientist.com
1
220
Reprogramming cellular senescence and aging clocks for advanced cancer immunotherapy pulse.ly/rxin5r7mmf

Reprogramming cellular senescence and aging clocks for advanced cancer immunotherapy

Molecular Cancer - Cellular senescence has gradually been recognized as a key process, which not only inhibits the occurrence of early tumors but also promotes advanced malignant progression...

link.springer.com
1
191
In the poll kids generally believed 49 years old was -- old! and, "One in five children believe adults stop having fun and exercising at 30-years-old and nearly half of those polled said they believed their parents were old." pulse.ly/61y1ernsgt

Ageing: What age do you think is old?

A new poll of 1,000 children has revealed what age children think adults are officially considered old.

bbc.co.uk
4
198
“ Whether we damaged the mitochondria or the telomeres we got dysfunctional T cells. There is crosstalk between the engine of the cell and the brains of the cell, the mitochondria, and the nucleus. something we didn’t appreciate in immune system.” pulse.ly/2whls2jkze
4
5
271
Mounting evidence suggests telomere shortening is an important research focus in interstitial lung disease (ILD) pulse.ly/n8bv4skors

Telomere Length a Promising Avenue in ILD Research | AJMC

Telomere length can be used in the diagnosis of interstitial lung diseases like idiopathic pulmonary fibrosis, but it likely also has therapeutic implications, according to a new report.

ajmc.com
1
1
5
267
Foxo3 enhanced human mesenchymal progenitor cells pulse.ly/aamxlhfetn

Rewriting destiny—gene-hacked stem cells ignite a revolution against aging

Cell Death & Disease - Rewriting destiny—gene-hacked stem cells ignite a revolution against aging

nature.com
1
4
215
Gene therapy, yes. pulse.ly/4aoqf4deyo

It Sure Looks Like Humans Have Found a Way to Reverse Aging

A landmark study shows this age-old tech is the key.

popularmechanics.com
2
7
29
936
The Role of the Senescence-Associated Secretory Phenotype in Cardiovascular Disease Among the Elderlyhttps://pulse.ly/sa2f6qm2iy
1
5
259
This study is among the first to show that the first weeks of life, when the immune system is naturally more tolerant, may be the optimal window for delivering gene therapies that would otherwise be rejected at older ages. pulse.ly/ebzhdkvyzv

1 shot at birth may protect kids from HIV for years

"This approach could help protect newborns in high-risk areas during the most vulnerable period of their lives."

futurity.org
1
3
8
255
Genetic risk variants don’t always cause disease, and outcomes can vary among carriers. Poeschla et al. suggest this is partly due to common variants—such as those affecting telomere length— pulse.ly/jwogepgqgv
1
8
238
Telomere fragility is linked to telomere length and telomerase activity. Lab tests confirmed that short telomeres were more fragile, especially in clones with lower telomerase activity.pulse.ly/nck3lh7g7d

Telomere fragility is associated with telomere length A Telomerase...

Download scientific diagram | Telomere fragility is associated with telomere length A Telomerase activity assessed by ddTRAP in PCS clones, normalized to PCS-8. SW39/TEL⁺ and IMRB/ALT⁺ cells (grey...

researchgate.net
1
5
291
T-cell lymphopenia is a key feature of immunodeficiency in telomere biology disorders and is linked to higher risks of serious infections, cancer, and reduced survival. pulse.ly/dmh8qa16ie
1
211
Those who developed kidney problems (AKI) had lower levels of Klotho. People with higher Klotho levels had better chances of recovery. Klotho was also a better warning sign of kidney issues than the usual test (creatinine). pulse.ly/ye3cbmjeq4

Clinical value of serum Klotho protein in patients with acute traumatic brain injury complicated by...

Scientific Reports - Clinical value of serum Klotho protein in patients with acute traumatic brain injury complicated by acute kidney injury

nature.com
1
2
313
Link Between Shortened Telomeres and Brain Pathology Mitigated by Modifiable Risk Factorshttps://pulse.ly/ew1sytfqjb
3
223
Double the risk? Variants in the homeostatic iron regulator (HFE) gene are prevalent among individuals of European ancestry and have been linked to an increased risk of dementia. pulse.ly/ss2s9ua7ro

Haemochromatosis Genotypes and Incident Dementia in a Prospective Study of Older Adults | Neurology

Background and ObjectivesVariants in the homeostatic iron regulator (HFE) gene are prevalent among individuals of European ancestry and have been linked to an increased risk of dementia. This study...

neurology.org
1
200
Load more