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BCB-Faller Group @BiochemMetal

Biometals and Biological Chemistry (BCB) Lab, Pr. Peter Faller Group, @unistra

Joined April 2021
  • Tweets 78
  • Following 253
  • Followers 420
23 Photos and videos
New post-doc position available in our team ! x.com/FrenchBIC_CNRS/status/…

FrenchBIC CNRS@FrenchBIC_CNRS
28 Nov 2024
Post doc position: design of a Bioinspired 64/67Cu Ligand for theranostic applications frenchbic.cnrs.fr/2024/11/28…
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BCB-Faller Group retweeted
Enrico Falcone@EnriFalc1
29 Jun 2024
Check out our pre-print about the impact of lysosomal pH on the pro-oxidant and anticancer activity of the Cu-Phenanthroline complex @ChemRxiv go.shr.lc/4cEkVkN @BiochemMetal @PROMOCSlab @MedUni_Wien @esrfsynchrotron
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Looking forward to it !
REGLIER Marius@MREGLIER
18 Oct 2023
We are please to announce the French-Japanese Symposium on BioInorganic chemistry organized with the @FrenchBIC_CNRS annual meeting in Marseille from 23 to 26 April 2024. @reseauSCF @RJ_SCF @ism2_fr @univamu @CNRS_dr12 @INC_CNRS More info: jfbic-symposium-2024.fr
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Bravo et Merci à Ryan, Sofija, Katharina et Nele pour avoir présenté, lors de la Fête de la Science #FDS2023, l'utilisation d'hydrogels biosourcés pour réduire notre consommation de plastique ! et merci à @jds_unistra et @CNRS pour l'organisation !
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Enrico Falcone@EnriFalc1
24 Jun 2023
Check out in @Metallomics my first paper as sole corresponding author, about the redox activity of Copper with biological reductants and its biological implications for therapeutic purposes @BiochemMetal @IlbertMarianne Thanks to @UniofNottingham for OA doi.org/10.1093/mtomcs/mfad0…

Revisiting the pro-oxidant activity of copper: interplay of ascorbate, cysteine, and glutathione

Abstract. Copper (Cu) is essential for most organisms, but it can be poisonous in excess, through mechanisms such as protein aggregation, trans-metallation

academic.oup.com
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Congratulations to Katharina for her first author publication! And thanks to all the collaborators including @CarlosPlatas9. pubs.acs.org/doi/10.1021/acs…

Derivatization of the Peptidic Xxx-Zzz-His Motif toward a Ligand with Attomolar CuII Affinity under...

Cu chelation in biological systems is of interest as a tool to study the metabolism of this essential metal or for applications in the case of diseases with a systemic or local Cu overload, such as...

pubs.acs.org
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Thanks Tim Storr @storr_tim for the visit to Strasbourg and the nice talk about the latest results from his groups, so nice that I forgot to take a picture. We wish a good trip to Grenoble.
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BCB-Faller Group retweeted
Enrico Falcone@EnriFalc1
6 Mar 2023
Thanks to a collaboration between @BiochemMetal @unistra and the group of Prof. Silvia Morante @unitorvergata, we characterized a key redox intermediate of the Copper-Amyloidβ complex by XAS at @esrfsynchrotron. Now Open Access in @angew_chem onlinelibrary.wiley.com/doi/…

Chasing the Elusive “In‐Between” State of the Copper‐Amyloid β Complex by X‐ray Absorption through...

The combination of X-ray induced photoreduction and thermal relaxation unravels the structure of an intermediate of the CuII/CuI Aβ1–16 redox cycling. The X-ray beam promotes CuII reduction to CuI...

onlinelibrary.wiley.com
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Check out our recent article with a perspective on interaction of labile metal ions and chelators in the blood! @EnriFalc1 @DaltonTrans pubs.rsc.org/en/Content/Arti…

Thermodynamics-based rules of thumb to evaluate the interaction of chelators and kinetically-labile...

Metal ions play a very important role in nature and their homeostasis is crucial. A lot of metal-related chemical research activities are ongoing that concern metal-based drugs or tools, such as...

pubs.rsc.org
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BCB-Faller Group retweeted
Enrico Falcone@EnriFalc1
24 Jan 2023
Interested in the interaction of labile metal ions and chelators in the blood? Check out @DaltonTrans (OA doi.org/10.1039/D2DT03875G) where we (@BiochemMetal) introduce the concept of pM(plasma) to take into account the real concentrations of plasma proteins and metals in the blood
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Hi ! We have a PhD position starting March the 1st, 2023. It is about rationally design metallo-peptides for the catalysis of radical C-C bond forming reactions. Want to know more ? Here is the full announcement #Strasbourg #PhDposition #biochemistry #AcademicTwitter
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Check out our latest article in @ChemicalScience about the first Cu(II) peptide shuttle that remediates amyloid-beta toxicity. Well done @umichaelokafor! pubs.rsc.org/en/Content/Arti…

Development of Cu(II)-specific peptide shuttles capable of preventing Cu–amyloid beta toxicity and...

Copper (Cu) in its ionic forms is an essential element for mammals and its homeostasis is tightly controlled. Accordingly, Cu-dyshomeostasis can be lethal as is the case in the well-established...

pubs.rsc.org
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What an exciting opportunity for Michael Okafor and @EnriFalc1 to present their work and meet the Cu community at the amazing @Cu2022_Sorrento!
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BCB-Faller Group retweeted
Alzheimer, Amyloids and Bioinorganic Chemistry@HureauLab
22 Sep 2022
New paper on the Ala-His-His peptide as an appropriate scaffold to remove and redox silence copper ions from the Alzheimer's-related Abeta peptide ! @Biomol_MDPI Check it out: doi.org/10.3390/biom12101327
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Our work on acrolein, copper and alpha-Synuclein advertised on @ChemistryViews !
Enrico Falcone@EnriFalc1
1 Sep 2022
I'm pleased that @ChemistryViews reports on my Master project about acrolein, copper and alpha-Synuclein published in @ChemEurJ Check it out chemistryviews.org/details/e…
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Dr. Laurent Raibaut and soon-to-be PhD Maxime Naudé presenting their research projects at #EPS2022 in Barcelona
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BCB-Faller Group retweeted
J. Am. Chem. Soc.@J_A_C_S
7 Aug 2022
Cu-Catalyzed Glutathione Oxidation Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Boosted at Lower pH @MedUni_Wien @UniCalPortale @unistra @reseauSCF @BiochemMetal #Cu #Glutathione #Oxidation #Thiosemicarbazone #Booster #Anticancer #Cancer pubs.acs.org/doi/10.1021/jac…

Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT...

Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role in maintaining redox cellular homeostasis. The thiols of two GSH molecules can be oxidized to the disulfide...

pubs.acs.org
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BCB-Faller Group retweeted
Enrico Falcone@EnriFalc1
6 Aug 2022
So glad to see our work just published in @J_A_C_S! This is the result of an interdisciplinary and international collaboration between @BiochemMetal @PROMOCSlab @PetraHellwig2 @KowolLab @MedUni_Wien. Thanks to @FWF_at for funding open access. Check it out pubs.acs.org/doi/10.1021/jac…

Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT...

Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role in maintaining redox cellular homeostasis. The thiols of two GSH molecules can be oxidized to the disulfide...

pubs.acs.org
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Congratulations to our PhD student Katharina Zimmeter who won a best poster award at #MBP2022 about Cu-responsive MRI agents. Well done Katharina!
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BCB-Faller Group retweeted
Pôle Scientifique EMPP@EmppPole
16 Jun 2022
#MBP2022 International Conference on Metal-Binding Peptides : Methodologies and Applications 1ère conférence internationale sur les #peptides liant les #métaux 🗓️ 5-8 juillet 2022 à #Nancy Organisée par le #LRGP et @BiochemMetal En savoir plus👉 empp.univ-lorraine.fr/mbp202…
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