IT’S NOT JUST AN OLD MAN’S DISEASE One of the biggest misconceptions in men’s health is that prostate cancer only affects older men. While prostate cancer is more common as men age, over the years I have met many men diagnosed in their 40s, many of whom had no symptoms at all. That is why conversations matter. In this clip, Bob Evans shares a message for young men about taking ownership of their health before a problem develops. He also reminds us that testicular cancer primarily affects younger men and that becoming familiar with your body is an important part of being proactive about your health. The goal is not to create fear. The goal is awareness. • Know your family history. • Know your numbers. • Pay attention to changes in your body. • Ask questions. • Establish a relationship with a primary care physician. • Don’t assume that feeling fine means everything is fine. Guidelines for PSA testing vary based on factors such as age, family history, race, and personal risk. The most important first step is having the conversation with your doctor and understanding what is appropriate for you. Earlier conversations can lead to earlier awareness. Earlier awareness can lead to earlier action. And earlier action may provide more options if a problem is found. Bob Evans has been living with advanced prostate cancer since 2009 and is a longtime Movember Ambassador and men’s health advocate. Take ownership of your health. Educational only. Not medical advice.

WHY WOMEN MATTER IN MEN’S HEALTH Ask almost any healthcare professional, and you’ll hear a similar story: many men arrive at appointments because someone in their life encouraged them to go. A wife. A girlfriend. A mother. A daughter. A sister. An aunt. A cousin. A friend. In this clip, Maheetha Bharadwaj, MD discusses the important role women often play in encouraging the men they care about to schedule checkups, follow up on symptoms, ask questions, and take their health seriously. Sometimes that encouragement may seem small. A reminder to make an appointment. A conversation about a symptom. A nudge to ask about PSA testing. But those conversations can help move a man from delaying care to taking action. Research has shown that married men, on average, tend to live longer than unmarried men. While there are many factors that may contribute to that difference, one possible explanation is the value of having someone who encourages healthy behaviors, preventative care, and medical follow-up. At the same time, this is not about placing responsibility for men’s health on women. As Dr. Bharadwaj explains, men must also be empowered to take ownership of their own health, learn their medical history, understand their risk factors, and participate actively in their healthcare decisions. To the women who continue encouraging the men in your lives to get checked, ask questions, and stay engaged in their health: thank you. Your influence may matter more than you realize. Featuring: Maheetha Bharadwaj, MD Urologist in Training, PGY-4 Educational only. Not medical advice.

LET’S NORMALIZE MEN’S HEALTH CONVERSATIONS We routinely talk about heart health, eyesight, and joint pain. Yet when it comes to the prostate, sexual health, or urinary symptoms, the conversation often stops. In this clip, Maheetha Bharadwaj, MD explains why we need to reduce the stigma surrounding these topics and treat them like any other aspect of our health. The reality is simple: silence can delay care. Many health concerns are only addressed because someone decided to speak up, ask a question, schedule a checkup, or start a conversation with a healthcare professional. Normalizing these topics opens the door to education, earlier evaluation, and more proactive healthcare decisions. It helps people feel comfortable seeking answers instead of suffering in silence. These aren’t taboo topics. They are part of our health, our quality of life, and our overall well-being. Every conversation matters. Every question matters. Sometimes the first step toward better health is simply being willing to talk about it. Featuring: Maheetha Bharadwaj, MD Urologist in Training, PGY-4 If there is a health concern you’ve been putting off discussing, consider starting the conversation with a trusted healthcare professional. Educational only. Not medical advice.

WHY CANCER RESEARCH MATTERS TO YOU When most people hear the words “cancer research,” they think of laboratories, data, and scientific papers. But at its core, cancer research is about helping people live longer, healthier lives by improving our ability to identify disease earlier and guide patients toward the right care. In this clip, Johannes Fahrmann, PhD, explains how his team at MD Anderson Cancer Center is working to develop blood-based biomarker tests. A biomarker is a measurable biological signal that can provide information about what is happening inside the body. Researchers are studying biomarkers to help identify individuals who may be at elevated risk of cancer and to better understand how disease develops and progresses. THE GOAL: CATCH IT EARLY As Dr. Fahrmann explains, the best opportunity for a cure is often when cancer is identified before it has the opportunity to spread throughout the body. Research advances don’t happen overnight. They are built through years of scientific investigation, clinical studies, and collaboration among researchers, physicians, patients, and families. This Men’s Health Month, take an active role in your health. Don’t skip your annual checkup. Know your numbers. Ask questions. Talk with your healthcare provider about your individual risk factors and recommended screening options. Johannes Fahrmann, PhD Cancer Prevention Researcher | MD Anderson Cancer Center Learn more about Dr. Fahrmann’s research: faculty.mdanderson.org/profi… Educational only. This content is not medical advice and should not replace discussions with your healthcare team.

AT 41, PROSTATE CANCER WAS “OUT OF THE QUESTION” When Gregory Jacob Jr. was referred to a urologist for an elevated PSA, he was told that prostate cancer was “probably out of the question” because of his age. But his PSA remained elevated. After additional follow-up and a biopsy, Gregory received the news no one expected: he had prostate cancer. His story is an important reminder that while prostate cancer is more common as men age, younger men can be diagnosed as well. Gregory was diagnosed at 41. I was diagnosed at 35. It is also a reminder that numbers matter. PSA is not a perfect test, but it can provide important information when interpreted in the context of a man’s age, family history, symptoms, prostate size, and other clinical factors. For Black men, these conversations are especially important. Black men are approximately 70% more likely to be diagnosed with prostate cancer and more than twice as likely to die from the disease compared with white men. Knowing your family history, understanding your personal risk factors, and having informed conversations with your healthcare provider can help you make informed decisions about your health. If you have not had a routine checkup recently, consider scheduling one. • Know your numbers. • Know your family history. • Ask your healthcare provider whether PSA testing is appropriate for you. • If you have concerns about your urinary or prostate health, ask whether a referral to a urologist makes sense. Gregory Jacob Jr. Prostate Cancer Survivor | Author | Men’s Health Advocate Learn more about Gregory’s work: triedandapproved.com/ Educational content only. This information is not medical advice and is not a substitute for consultation with a qualified healthcare professional.

THE SYMPTOM I IGNORED FOR YEARS At age 41, Gregory Jacob Jr. was diagnosed with prostate cancer. Looking back, he recalls noticing a change in his urinary function years earlier, but assumed it was something minor and did not seek medical attention right away. In this clip, Gregory shares how a simple question from his doctor and encouragement from his wife led him to mention a concern he had been dismissing for years. His story is an important reminder that persistent changes in your health deserve attention. While urinary symptoms can have many possible causes, including benign conditions such as an enlarged prostate (BPH), ongoing concerns should be discussed with a healthcare provider rather than dismissed or ignored. For Black men, the conversation is especially important. Black men are approximately 70% more likely to be diagnosed with prostate cancer and more than twice as likely to die from the disease compared with white men. Knowing your family history, understanding your personal risk factors, and talking with your doctor about screening can help you make informed decisions about your health. If something doesn’t feel right, don’t ignore it. Schedule a checkup, discuss your concerns with your healthcare provider, and ask whether further evaluation or a referral to a urologist is appropriate. Gregory Jacob Jr. Prostate Cancer Survivor | Author | Men’s Health Advocate Learn more about Gregory’s work: triedandapproved.com/ Educational content only. This information is not medical advice and is not a substitute for consultation with a qualified healthcare professional.

Diagnosed at 41. Now He’s Helping Save Lives. At age 41, Gregory Jacob Jr. was diagnosed with prostate cancer. Today, he is using his experience to educate and empower others, particularly Black men, who face a higher risk of being diagnosed with and dying from the disease. In this clip, Gregory shares a simple but important message: know your numbers and talk with your doctor about prostate cancer screening. Since his diagnosis, Gregory has become a passionate advocate for men’s health, speaking openly about the importance of family history, self-advocacy, and breaking the silence and stigma that often prevent men from seeking help. His story is also a reminder that prostate cancer is not exclusively an older man’s disease. Gregory was diagnosed at 41. I was diagnosed at 35. Conversations about risk factors, family history, and screening matter. If you have concerns, symptoms, a family history of prostate cancer, or questions about your personal risk, talk with your healthcare provider. This is the first in a series of conversations with Gregory as he shares his prostate cancer journey, advocacy efforts, and lessons learned since his diagnosis. Gregory Jacob Jr. Prostate Cancer Survivor | Author | Men’s Health Advocate Learn more about Gregory’s work: triedandapproved.com/ Educational content only. This information is not medical advice and is not a substitute for consultation with a qualified healthcare professional.

TAKE OWNERSHIP OF YOUR HEALTH After living with advanced prostate cancer for 17 years, what is the one thing Bob Evans hopes men take away from his story? Not fear. Not regret. Action. In this clip, Bob shares a message that aligns closely with what I’ve learned during my own 16-year prostate cancer journey. Through my work with Blue Cure, I’ve spoken with countless patients, caregivers, and medical experts over the years. One lesson continues to stand out: your health is too important to leave to chance. • Know your family history. • Know your numbers. • Pay attention to changes in your body. • Ask questions. • Don’t assume that feeling fine means everything is fine. Bob was diagnosed with advanced prostate cancer at age 48. His younger brother was diagnosed earlier and caught it before it had spread. That difference changed the course of their journeys. One of the most powerful things Bob says in this conversation is: “I’m gonna own my own healthcare. I’m gonna own my health journey.” That mindset matters. Whether you’re a man who has never discussed PSA testing, someone currently on Active Surveillance, or a caregiver encouraging a spouse, father, brother, or friend to get checked, knowledge can lead to action. June is Men’s Health Month, but this message applies every single day of the year. Talk with your doctor about your personal risk factors, family history, and whether PSA testing is appropriate for you. Bob Evans has been living with advanced prostate cancer since 2009 and is a longtime Movember Ambassador and men’s health advocate. Take ownership of your health. Educational only. Not medical advice.

DOES ADVANCED PROSTATE CANCER TREATMENT EVER STOP? Many people assume that an advanced prostate cancer diagnosis means a man will be on medication continuously for the rest of his life. In this clip, Bob Evans shares his personal experience living with advanced prostate cancer since 2009. How It Works: Slowing the Cancer After surgery and radiation, Bob continued to have an elevated Prostate-Specific Antigen (PSA), a blood marker commonly used to monitor prostate cancer. His doctors then placed him on medications called Eligard and Lupron. These are forms of Androgen Deprivation Therapy (ADT), also known as hormone therapy. Because prostate cancer cells often rely on testosterone to grow, ADT works by dramatically lowering testosterone levels to help slow or control the disease. The Strategy: Intermittent Treatment What makes Bob’s story particularly interesting is that his doctors have managed his cancer using an intermittent treatment approach. In Bob’s case: • Hormone therapy is used to drive his PSA down to an undetectable level. • He then comes off the medication and is monitored closely with PSA blood tests every three months. • If his PSA begins to rise again, treatment is restarted. As Bob explains, spending time off medication can mean fewer treatment-related side effects, more energy, and an improved quality of life. A Bigger Lesson One of the most important takeaways from Bob’s story is that advanced prostate cancer management has changed dramatically over the last two decades. Today, many men are living longer because of advances in imaging, monitoring, and treatment. Treatment plans vary from patient to patient. Bob is sharing his personal experience, and not every man with advanced prostate cancer will follow the same treatment strategy. Bob Evans has been living with advanced prostate cancer since 2009 and serves as a longtime Movember Ambassador and men’s health advocate. *If you have never discussed PSA testing with your doctor, don’t wait for symptoms. Prostate cancer often develops silently. Educational only. Not medical advice.

PRE-CANCER EXPLAINED: DOES IT ALWAYS BECOME CANCER? Not necessarily. One of the most common misconceptions is that a pre-cancerous cell will inevitably become cancerous. According to Johannes Fahrmann, PhD, Cancer Prevention Researcher at MD Anderson Cancer Center, that is not how biology works. In this clip, Dr. Fahrmann explains that pre-cancer is an abnormal cell that is behaving differently than a healthy cell, but it has not yet transformed into a cancer cell. He uses a simple analogy: Imagine driving a car with one foot on the gas pedal and one foot on the brake. A cell has begun to change to an abnormal ‘pre-cancerous’ cell [left foot is on the gas], but the body’s natural protective mechanisms are still helping keep it under control [right foot is on the break]. It has not yet become cancer. It is when the body is no longer able to keep on the ‘break’ that the pre-cancer cell ‘accelerates’ towards becoming cancerous. Pre-cancerous changes often cause no symptoms. That is one reason regular checkups, appropriate screening, and understanding your health numbers can be so important. Perhaps the most reassuring takeaway: We walk around with abnormal cells all the time. Our immune system is constantly working to identify and eliminate many of them before they ever become a problem. That does not mean all abnormal cells disappear. It also does not mean all pre-cancerous cells become cancer. Understanding that difference can help reduce fear and lead to more informed conversations about prevention, screening, and early detection. Johannes Fahrmann, PhD Cancer Prevention Researcher MD Anderson Cancer Center Learn more about Dr. Fahrmann’s research: faculty.mdanderson.org/profi… This Men’s Health Month, schedule a checkup, know your numbers, and ask questions until you understand what those numbers mean. Educational only. Not medical advice.

WHAT DOES “HIGH RISK” REALLY MEAN? When many people hear the words “high risk,” they assume cancer is inevitable. But that is not what high risk means. In this clip, Johannes Fahrmann, PhD, Cancer Prevention Researcher at MD Anderson Cancer Center, explains an important distinction that can help reduce confusion and fear. Being at higher risk does not mean you have cancer. It does not mean you will develop cancer. It means your probability, or odds, of developing cancer is higher than that of the average person. Think of risk as a forecast, not a diagnosis. Dr. Fahrmann explains that there are different types of risk: • Some people have a higher lifetime risk because of factors such as family history or inherited genetic mutations. • Others may have a higher near-term risk, meaning their likelihood of developing cancer over the next few years is greater than average. He also explains the difference between three terms that are often confused: • Risk testing asks: How likely am I to develop cancer in the future? • Early detection testing asks: Is there a signal that cancer may already be present? • Diagnostic testing asks: Can we confirm whether cancer is actually there? Those distinctions matter. One of the goals of modern medicine is to identify people at higher risk before symptoms develop so they can receive appropriate screening, monitoring, and follow-up care. Knowledge does not have to create fear. Knowledge can create awareness. Awareness can create action. Learn more about Dr. Fahrmann’s work: faculty.mdanderson.org/profi… This is the second clip in our educational series with Johannes Fahrmann, PhD, Cancer Prevention Researcher at MD Anderson Cancer Center. Follow Blue Cure for more expert-led conversations on cancer prevention, early detection, and men’s health. Educational only. Not medical advice.

WHAT DO YOUR LAB RESULTS REALLY MEAN? For years, Blue Cure has encouraged men to “Know Your Numbers.” Most people think of numbers like PSA (prostate-specific antigen), testosterone, cholesterol, low-density lipoprotein (LDL) cholesterol, blood glucose, and hemoglobin A1c (HbA1c) as just standard lab results. In this first clip from our conversation, Johannes Fahrmann, PhD, explains an important concept many patients have heard but may not fully understand: biomarkers. A biomarker is a biological signal that provides information about what may be happening inside your body. Biomarkers can provide important information about what may be happening inside your body and help healthcare teams better understand health risks and trends over time. In this foundational clip, Dr. Fahrmann breaks down how biomarkers are used across medicine: • PSA provides a signal regarding prostate health. • Glucose and HbA1c provide insight into blood sugar regulation. • Cholesterol and LDL provide important clues about cardiovascular health. One of the most important lessons in men’s health is that you cannot manage what you do not measure. Many of our daily choices, including nutrition, exercise, sleep, and stress management, can influence metabolic and cardiovascular markers over time. Knowing your baseline numbers gives you a starting point to track trends, ask better questions, and make more informed decisions alongside your healthcare team. Knowledge does not have to create fear. Knowledge can create awareness. Awareness can create action. Action can create change. This is the first clip in a new educational series with Johannes Fahrmann, PhD, Cancer Prevention Researcher at MD Anderson Cancer Center. Over the coming weeks, we’ll explore biomarkers, cancer risk, early detection, active surveillance, lifestyle factors, and the future of precision medicine. Educational only. Not medical advice.

NO PROSTATE BIOPSY RIGHT NOW? THE CONVERSATION ISN’T OVER Many men understandably feel relieved when they hear they do not need a prostate biopsy right away. But as Adam B. Weiner, MD, explains in this clip, that does not necessarily mean prostate cancer screening and follow-up are over. A prostate biopsy is a procedure used to collect small samples of prostate tissue to look for cancer. While some men may benefit from a biopsy, others may be candidates for continued monitoring based on their individual situation. As Dr. Weiner explains, a decision not to perform a biopsy today may simply mean that ongoing monitoring is the most appropriate next step. That monitoring may include: • Periodic PSA (prostate-specific antigen) blood testing • Follow-up with a primary care physician or urologist • Comparing new results with prior PSA tests and imaging studies, such as MRI (magnetic resonance imaging) The goal is not simply to perform more testing. The goal is to make informed decisions based on the best available information while avoiding unnecessary procedures when appropriate. If you’ve ever had an elevated PSA but were told a prostate biopsy wasn’t needed right away, did your doctor discuss a follow-up plan with you? And if you’re unsure whether PSA testing should be part of your health conversations, talk with a doctor you trust. Ask questions and understand what makes sense for your individual situation. Featuring: Adam B. Weiner, MD / @Adam_Weiner535 Urologic Oncologist Cedars-Sinai Medical Center Learn more: adamweinermd.com/ Educational content only. Not medical advice. Always consult your physician or qualified healthcare professional regarding your individual health decisions.

HIGH PSA? WHAT HAPPENS NEXT? Many men assume that an elevated PSA automatically means a prostate biopsy is next. In reality, the process is often more nuanced. In this clip, Adam B. Weiner, MD, urologic oncologist at Cedars-Sinai Medical Center, explains how urologists use multiple tools to help determine who may benefit from a biopsy and who may be safely monitored further before taking that step. PSA (prostate-specific antigen) is a protein produced by the prostate and measured with a blood test. While an elevated PSA can sometimes be associated with prostate cancer, it can also be influenced by other factors, including benign prostate enlargement, inflammation, and other non-cancerous conditions. As Dr. Weiner explains, an elevated PSA may be followed by additional evaluation, which can include: • Repeat PSA testing to confirm the result • Free and Total PSA, a more detailed PSA blood test • Prostate Health Index (PHI), a blood test that helps estimate the likelihood of finding clinically significant prostate cancer • 4Kscore, a blood test that helps estimate the risk of aggressive prostate cancer • Multiparametric MRI (magnetic resonance imaging), an imaging study that helps identify areas of concern within the prostate The goal is not simply to perform more testing. The goal is to perform the right testing for the right patient at the right time. If you’ve had an elevated PSA, talk with a doctor you trust about what additional evaluation, if any, may be appropriate for your individual situation. Featuring: Adam B. Weiner, MD Urologic Oncologist Cedars-Sinai Medical Center Learn more: adamweinermd.com/ Educational content only. Not medical advice. Always consult your physician regarding your personal medical decisions.

MANAGING TREATMENT SIDE EFFECTS FOR ADVANCED PROSTATE CANCER One of the biggest misconceptions about advanced prostate cancer is that men always physically “feel” the cancer spreading throughout their body. In reality, many men describe the treatment side effects as more noticeable than the cancer itself. In this clip, Bob Evans shares how the fatigue and lower energy he experiences are primarily related to the medication used to suppress testosterone, a common treatment approach for advanced prostate cancer often called hormone therapy or Androgen Deprivation Therapy (ADT). Because prostate cancer cells often rely on testosterone to grow, lowering testosterone levels can help slow or control the spread of the disease. But that can also come with side effects, including fatigue, hot flashes, reduced energy, changes in mood, loss of muscle mass, and other physical or emotional challenges. Bob also shares something incredibly important that his medical oncologist told him at the time of his diagnosis 17 years ago: “If you can tolerate the side effects, we can keep the cancer from spreading.” That conversation gave him hope. Today, Bob Evans has been living with advanced prostate cancer since 2009 and continues using his voice to encourage and educate other men as a longtime Movember Ambassador and men’s health advocate. Advanced prostate cancer is serious. But many men are living longer because of earlier detection, improved treatments, advanced imaging, ongoing monitoring, and better long-term management strategies. If you or someone you love is living with advanced prostate cancer, stay engaged with your medical team, communicate openly about side effects, stay on top of follow-up care, and do not lose hope. And for men who have never discussed PSA testing or family history with a physician or urologist, start the conversation. Prostate cancer often develops silently in its earlier stages, and earlier detection may provide more treatment options before the cancer spreads. Take ownership of your health. Educational only. Not medical advice.

PSA SCREENING: 35, 40, OR 50? Why do recommendations sometimes differ? As someone diagnosed with prostate cancer at age 35, I’ve spent years hearing different perspectives on when men should begin discussing PSA screening. Many men are surprised to learn that different physicians may recommend discussing PSA screening at different ages. Part of the confusion comes from the fact that screening guidelines are often designed for large, average-risk populations. But individual patients are not averages. In this clip, Adam B. Weiner, MD, urologic oncologist at Cedars-Sinai Medical Center, explains why a urologist may approach prostate cancer screening differently than a primary care setting. He also discusses an important concept many men have never heard: a baseline PSA obtained at age 35 or 40 may provide insight into a man’s future prostate cancer risk, even when cancer is not present at that time. PSA (prostate-specific antigen) is a protein produced by the prostate and measured with a simple blood test. PSA testing can help identify potential prostate concerns, but interpreting the result often requires context. Factors that may influence screening discussions include: • Age • Family history of prostate cancer • Race and ethnicity • Overall health • Personal medical history • Prior PSA results The goal is not simply to find cancer. The goal is to help each man make informed decisions based on his individual situation. If you’re unsure when PSA screening should be part of your health conversations, talk with a doctor you trust. Ask questions. Understand your personal risk profile. And make sure your screening decisions are based on your individual situation, not age alone. Featuring: Adam B. Weiner, MD / @Adam_Weiner535 Urologic Oncologist Cedars-Sinai Medical Center Learn more: adamweinermd.com/ Educational content only. Not medical advice. Always consult a qualified healthcare professional regarding your individual health decisions.

PSA SCREENING: 35, 40, OR 50? Why do recommendations sometimes differ? As someone diagnosed with prostate cancer at age 35, I’ve spent years hearing different perspectives on when men should begin discussing PSA screening. Many men are surprised to learn that different physicians may recommend discussing PSA screening at different ages. Part of the confusion comes from the fact that screening guidelines are often designed for large, average-risk populations. But individual patients are not averages. In this clip, Adam B. Weiner, MD, urologic oncologist at Cedars-Sinai Medical Center, explains why a urologist may approach prostate cancer screening differently than a primary care setting. He also discusses an important concept many men have never heard: a baseline PSA obtained at age 35 or 40 may provide insight into a man’s future prostate cancer risk, even when cancer is not present at that time. PSA (prostate-specific antigen) is a protein produced by the prostate and measured with a simple blood test. PSA testing can help identify potential prostate concerns, but interpreting the result often requires context. Factors that may influence screening discussions include: • Age • Family history of prostate cancer • Race and ethnicity • Overall health • Personal medical history • Prior PSA results The goal is not simply to find cancer. The goal is to help each man make informed decisions based on his individual situation. If you’re unsure when PSA screening should be part of your health conversations, talk with a doctor you trust. Ask questions. Understand your personal risk profile. And make sure your screening decisions are based on your individual situation, not age alone. Featuring: Adam B. Weiner, MD Urologic Oncologist Cedars-Sinai Medical Center Learn more: adamweinermd.com/ Educational content only. Not medical advice. Always consult a qualified healthcare professional regarding your individual health decisions.

MANAGING TREATMENT SIDE EFFECTS FOR ADVANCED PROSTATE CANCER One of the biggest misconceptions about advanced prostate cancer is that men always physically “feel” the cancer spreading throughout their body. In reality, many men describe the treatment side effects as more noticeable than the cancer itself. In this clip, Bob Evans shares how the fatigue and lower energy he experiences are primarily related to the medication used to suppress testosterone, a common treatment approach for advanced prostate cancer often called hormone therapy or Androgen Deprivation Therapy (ADT). Because prostate cancer cells often rely on testosterone to grow, lowering testosterone levels can help slow or control the spread of the disease. But that can also come with side effects, including fatigue, hot flashes, reduced energy, changes in mood, loss of muscle mass, and other physical or emotional challenges. Bob also shares something incredibly important that his medical oncologist told him at the time of his diagnosis 17 years ago: “If you can tolerate the side effects, we can keep the cancer from spreading.” That conversation gave him hope. Today, Bob Evans has been living with advanced prostate cancer since 2009 and continues using his voice to encourage and educate other men as a longtime Movember Ambassador and men’s health advocate. Advanced prostate cancer is serious. But many men are living longer because of earlier detection, improved treatments, advanced imaging, ongoing monitoring, and better long-term management strategies. If you or someone you love is living with advanced prostate cancer, stay engaged with your medical team, communicate openly about side effects, stay on top of follow-up care, and do not lose hope. And for men who have never discussed PSA testing or family history with a physician or urologist, start the conversation. Prostate cancer often develops silently in its earlier stages, and earlier detection may provide more treatment options before the cancer spreads. Take ownership of your health. Educational only. Not medical advice.

HOW PSMA PET SCANS TRACK ADVANCED PROSTATE CANCER When prostate cancer spreads beyond the prostate gland into other parts of the body, it is considered advanced or metastatic prostate cancer. In this clip, Bob Evans explains how doctors are monitoring his cancer using a PSMA PET scan. PSMA stands for Prostate-Specific Membrane Antigen, a protein commonly found on prostate cancer cells. During the scan, a special imaging fluid is injected into the body that attaches to prostate cancer cells and helps “light up” areas where cancer may be located. Bob shares that his scans have shown small areas of cancer in parts of his chest and pelvic region. But he also received encouraging news: after comparing scans from three years apart, there appeared to be slightly less cancer activity than before. That’s an important reminder that advanced prostate cancer does not always mean immediate hopelessness. With ongoing monitoring, experienced doctors, evolving imaging technology, and treatment, many men are able to manage this disease long term. Bob Evans has been living with advanced prostate cancer since 2009 and is a longtime Movember Ambassador and men’s health advocate, using his voice to help educate and encourage other men facing prostate cancer. One of the biggest challenges with prostate cancer is that it often causes no symptoms in its earlier stages. If you’ve never discussed PSA testing, family history, or prostate cancer risk with your physician or a urologist, start the conversation. Earlier detection may provide more treatment options and can help identify prostate cancer before it spreads. Take ownership of your health. Educational only. Not medical advice.

POSITIVE ATTITUDE. GREAT DOCTORS. NEVER LOSE HOPE. When Bob Evans was diagnosed with advanced prostate cancer in 2009, he made a decision: “…I’m going to beat this and it’s not going to beat me.” Seventeen years later, Bob continues to live with advanced prostate cancer while advocating for men around the world through his longtime work with Movember as a men’s health Ambassador. In this clip, Bob shares an important message for men facing an advanced diagnosis: hope still matters. So does finding experienced doctors, staying engaged with treatment, asking questions, and continuing to move forward one step at a time. Advanced prostate cancer may require long-term management, including surgery, hormone therapy, radiation, ongoing PSA monitoring, and regular follow-up with a medical team. But Bob’s story is a reminder that many men continue working, traveling, exercising, spending time with family, and living meaningful lives while navigating this disease. His message is not about ignoring reality. It is about refusing to surrender to it. If you or someone you love has been diagnosed with prostate cancer, stay engaged with your doctors, stay on top of follow-up care, and do not lose hope. And for men who have never discussed PSA testing, bring it up with your physician or a urologist. Early conversations and awareness can help identify prostate cancer before it spreads and may provide more treatment options. Take ownership of your health. Educational only. Not medical advice.