“I ❤️ Cholesterol; but my ❤️ doesn’t”  However, there’s much much more to cholesterol than that. We study how we and our cells balance this Jekyll/Hyde molecule

Joined September 2018
73 Photos and videos
Brown Lab UNSW retweeted
One of the best things about science is speculating on how to solve a fascinating problem. Check out our paper "A paREDOX in the control of cholesterol biosynthesis" in #BioEssays. doi.org/10.1002/bies.2024000… @UNSWScience @UNSWBABS (1/3)
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Brown Lab UNSW retweeted
Thrilled to have the final pieces of my PhD work with @BrownLabUNSW published in @jbiolchem - huge thanks go to @TinaBNguy for the effort to get it across the line after my departure for the UK, and also to @ximingDu for the beautiful microscopy! (🧵1/4) doi.org/10.1016/j.jbc.2024.1…

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Brown Lab UNSW retweeted
Very excited to uncover SC5D as the 6th cholesterol synthesis enzyme targeted by our favourite E3 ligase MARCHF6! Check out our findings in @BBAjournals doi.org/10.1016/j.bbalip.202… @UNSWScience
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Brown Lab UNSW retweeted
CO2, regulation and metabolism. @NicoleMFenton @BrownLabUNSW explore a #PLOSBiology study that provides the first link between #CarbonDioxide and the master transcriptional regulator of #cholesterol homeostasis. Paper: plos.io/3QEDs7f Primer: plos.io/46sLSV2
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Our latest paper just out! @NatMetabolism
Check out our commentary on the latest landmark study from Peter Tontonoz's group @UCLA! A staggering amount of work solidifying the role of plasma membrane-to-ER #cholesterol transport in systemic lipid balance. doi.org/10.1038/s42255-022-0… @BrownLabUNSW @UNSWBABS @UNSWScience (1/2)
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Brown Lab UNSW retweeted
Great way to end the year with my first first-author publication - a mini-review looking at the interplay between sugar and cholesterol metabolism. @UNSWScience🧵(1/3) sciencedirect.com/science/ar…

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A new way to control our favourite E3 ligase MARCHF6! With our lab neighbours @voineagulab @akira_gokool, we found MARCHF6 forms a circRNA to control protein levels of itself and its substrate SM. New publication by @qian_lydia and @laurajsharpey out now! authors.elsevier.com/a/1fuio…

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Last presentation for the Brown Lab at @ComBio2022 Nicole Fenton! @NicoleMFenton #combio2022
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Now we have Isabelle Capell-Hattam presenting her work from her recently submitted PhD thesis! @isabelle_CapHat #combio2022
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Posters by Lydia Qian and Laura Sharpe on now! #combio2022 @qian_lydia @laurajsharpey
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Great presentation by Hudson Coates @hudsonwilco!
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Brown Lab is excited to be at @ComBio2022! There are six presentations from our lab over the next three days. Please feel free to reach out if you want to chat with us! #combio2022
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On Friday, @isabelle_CapHat at 10:30 am in Eureka Room 2, @NicoleMFenton at 4:10 pm in Hospitality Suite 1, and @TinaBNguy at poster 212.
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Looking forward to meeting you!
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Brown Lab UNSW retweeted
A big milestone today with @BrownLabUNSW celebrating 20 years with @UNSWScience !!! It is amazing to think how many young researchers have walked through the lab and emerged as actual real life scientists thanks to Andrew's mentoring and guidance.
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Early signals of spring in Sydney bring the @BrownLabUNSW out for icecream.
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Lab meeting in lockdown with a random pet thrown in for good measure @UNSWBABS @UNSWScience
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We are saddened to say goodbye to @Nicola_A_Scott who’s been with the lab for five years (Hons PhD), and wish her all the best as she takes up an exciting post-doc in @Neal_Lab. Nicola is modelling her PhD artwork (the many tentacles of an E3 ubiquitin ligase).
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