Yves Brun's lab, Canada 150 Research Chair in Bacterial Cell Biology. Bacteria and cool stuff they do and let us observe. @BrunlabCaulo@mstdn.science

Joined October 2013
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Fantastic collaboration with @PhilGuo1 and his team to determine the in situ structure of Tad pili. Great work from Greg Whitfield for our part of the work!
Great collaboration with @BrunLabCaulo for resolving the Tad pilus machine structure by cryo-electron tomography. Beautiful work by graduate students James Iarocci and Ryu Williston from our lab! doi.org/10.1101/2025.11.05.6…
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Please repost: Postdoc position in antibiotic discovery in a multidisciplinary project w. high-throughput approaches, microscopy, AI, and hit-to-lead optimization @UMontreal @med_umontreal @Mila_Quebec @IRIC_umontreal. Apply @ ML.Antibiotics@gmail.com. See lnkd.in/dVVk4N3s
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Brun Lab retweeted
We're currently looking for a PostDoc position at @UMontreal and @Mila_Quebec to work on a multi-modal bacteria representation for anti-biotic discovery, including multiple modalities: - Phenomics - Transcriptiomics - Structural bio - Viability curves - ADME The work will be done alongside biologists from brunlab.com DM me for more info

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Brun Lab retweeted
🚨 Call for a POSTDOC in machine learning for drug discovery at @UMontreal 💊 The position will be part of a large collaboration with @BrunLabCaulo Audrey Durand @dom_beaini Anne Marinier @IRIC_umontreal @Mila_Quebec. All details here: brunlab.com/jobs/open-positi… Please RT 💜

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Starting to work on my talk at Cambridge tomorrow. Different topic. No Guinness yet.
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On my way to @WarwickLifeSci to give a seminar tomorrow on a relatively new project. Thanks for the invitation @davidroper2
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19 Nov 2024
Excited to present our resent progress on our antibiotic discovery pipeline at the @bioMerieuxCA AMR Symposium in Toronto Nov. 20th at 11:30 AM.
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2 days left. Asst/Assoc Prof position in bacteriology, Université de Montréal. Deadline ***Nov. 15*** come join our growing community of bacteriologists. BTW, à propos of nothing, Canada is the USA’s Bluesky!
Please RT: Nov. 15 deadline! We are building a strong bacteriology community @UMontreal @med_umontreal, including recent hires @S_vanTeeffelen @FredoLeRoux & myself. Moving to Montréal in 2018 is one of the best career decisions I made. Come join us! jobs.sciencecareers.org/job/…
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12 Nov 2024
How does your favorite species elongate?🧵"Phenotypic plasticity in bacterial elongation among closely related species" by @mariedelaby, @liuyang1125 et al buff.ly/48Kw96x. How do cells elongate, all over, poles, middle? Close species do it the same way right? Not quite!
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Not only do these three closely related species have different modes of cell elongation but they also have different morphologies. Could the elongation mechanisms in these species influence their morphology or vice versa?
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Expanding our analysis, we find a distribution of elongation modes, suggesting their evolution is shaped by multiple, independent events, implying a high degree of phenotypic plasticity in the regulation of localized elongation modes. How does your favorite species elongate?
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Brun Lab retweeted
Now out in NSMB for those who missed our biorxiv back in 2023.. rdcu.be/dZSPQ

The missing piece in the bacterial #ESCRT-III story.. #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😎😵‍💫 Wonderful collaboration with @Colom_D @RouxLab… 1/2 biorxiv.org/content/10.1101/…
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