Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun. Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology. Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier. With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

12 years ago, I got the opportunity to intern at an “exciting startup” I accepted That company? It wasn’t SpaceX. In fact, it ran out of money and went out of business a few months after I joined.

German tour guide is using a German flag in Germany to guide his group. 5 police officers stop him. The flag is offensive to those who are not identifying with Germany. What the f&ck?

Saving LA - Phase III

We built the world's largest cargo drone @poseidonaero

Somewhere a manufacturing engineer and handful of techs are absolutely seething

Get paid to wait The Claude Code spinner might be the most watched line on Earth. So I turned it into an ad marketplace. Advertisers bid on it. You keep 50% of the money. Install the extension → get cash from ads. Introducing Kickbacks