🫀Influenza may be a major contributor to adverse outcomes in atrial fibrillation. A nationwide Danish study by @Espersen_C and colleagues from @CTCPR_, published in Heart Rhythm, followed >140,000 patients with AF across 8 influenza seasons. Key findings • Influenza activity was associated with: — 298 excess deaths/year — 86 excess cardiovascular deaths/year — 387 excess pneumonia/influenza hospitalizations/year • The burden was substantially higher than in individuals without AF 💡Influenza prevention may be an overlooked opportunity to improve outcomes in patients with AF. Study link: sciencedirect.com/science/ar… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes

💉Does diabetes change the benefit of high-dose influenza vaccination? A new prespecified DANFLU-2 analysis by @AnneBjergn and colleagues from @CTCPR_, published in @JAMAInternalMed, included 332,438 adults aged ≥65 years. Key findings • High-dose influenza vaccination was associated with lower risk of cardiorespiratory, cardiovascular, and influenza-related hospitalizations compared with standard-dose vaccination • Benefits were consistent in adults with and without diabetes • The largest cardiorespiratory benefit was observed in those with diabetes duration >5 years (rVE 20.4%) 💡High-dose influenza vaccines may help reduce severe respiratory and cardiovascular outcomes in older adults, regardless of diabetes status. Full study link: jamanetwork.com/journals/jam… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @RebeccaCHarris @matslassen @KristofferSkaar @niklasdj1 @AM_reimer @dons_maria @KBernholm @fdavidovski_MD @LisaSteenDuus @camillaiottosen @Espersen_C @drJBorchsenius @katjabartholdy @AdamLanghoff @MortenSengelov @MananPareekMD @KiraJanstrup

🏆A while ago, our founder, Professor @TorBiering, received @cardio_dk and Hjerteforeningen Research Award 2026. The award recognizes outstanding contributions to cardiovascular research and is a well-deserved recognition of Tor's many years of dedication to advancing cardiovascular science, building innovative research infrastructure, and mentoring the next generation of researchers. We are incredibly proud to see this achievement recognized. Congratulations from your team at @CTCPR_ ! 👏 Read more about Tor and the award below 👇 via.ritzau.dk/pressemeddelel… @CopCard @RigsHeart @HGHHjerte @Stenodiabetes

🫀New @CTCPR_ study in The International Journal of Cardiovascular Imaging Mathilde Zeuthen Pedersen and colleagues show that cardiac diastolic dysfunction is strongly linked to kidney failure risk in CKD. Study design 731 CKD patients followed for 3.8 years with comprehensive echocardiography. Key findings • Severe LV diastolic dysfunction → ~3x higher risk of ESKD • E/e’ >14 → >3x higher risk • Consistent signal across diastolic markers 💡Cardiac function may help identify CKD patients at highest risk of progression. 📄See full study: link.springer.com/article/10… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @niklasdj1 @matslassen @KristofferSkaar @fwemmer1

💉 What if we looked beyond statistical significance? A new Bayesian re-analysis of the DANFLU-1 trial by Daniel Modin and colleagues from @CTCPR_, published in Human Vaccines & Immunotherapeutics, included 12,477 adults aged 65–79 years. Key insights: • >95% probability that high-dose vaccination reduces all-cause mortality • >95% probability of reducing influenza/pneumonia hospitalizations • Findings were consistent across non-informative, evidence-based, and skeptical priors The results strengthen the evidence supporting high-dose influenza vaccination in older adults. 📄 See full study: tandfonline.com/doi/full/10.… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @niklasdj1 @RebeccaCHarris @AM_reimer

🫀Who benefits from subclinical AF screening? A LOOP trial substudy led by @fwemmer1 and colleagues from @CTCPR_, published in the Journal of the @American_Heart, tested whether echocardiographic markers modify the effect of ILR-based SCAF screening on stroke. Study design 1,422 participants were randomized to ILR screening vs usual care (5.5-year follow-up), with echocardiography in a subset (24%). Key insights • No overall stroke reduction with ILR screening (3.9% vs 3.8%) • Conventional echo measures showed no effect modification • Only left atrial contraction strain identified benefit (HR 0.38 in low strain) 💡Atrial function—not standard echo—may help identify patients who benefit from screening. Full study link: ahajournals.org/doi/10.1161/… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @PeterGodsk

Extremely proud of friend, colleague, and boss, @TorBiering, for receiving the 2026 Danish Society of Cardiology & Danish Heart Foundation @cardio_dk Research Prize! This award is in recognition of his massively innovative, outstanding research efforts - Tor, you’re the man!

Congrats @TorBiering. So well deserved. Brilliant scientist, researcher, colleague and friend. Thanks for inspiring us! @CTCPR_

🫀Can cardiac myosin inhibition improve outcomes in non-obstructive HCM? A new publication by Kaveh Hosseini and colleagues from @CTCPR_, published in Heart Failure Review, highlights findings from the phase 3 ODYSSEY-HCM trial evaluating mavacamten in symptomatic nHCM. Key findings: • Clear biomarker and imaging effects • No significant improvement in functional capacity or quality of life • Reversible reductions in EF required dose interruption in some patients 💡Target engagement alone may not be enough to achieve meaningful clinical benefit in nHCM. Study link: link.springer.com/article/10… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes

🫀 What is the long-term cardiovascular impact of RSV infection? New nationwide Danish data study from Anders Hviid and colleagues from @CTCPR_, published in @JAMANetworkOpen, followed adults ≥45 years with laboratory-confirmed RSV for 1 year using Danish health registries. Key findings: - RSV was associated with a significant excess risk of cardiovascular events - Highest risks were seen in hospitalized patients, older adults, and those with CVD or diabetes - Cardiovascular risk after RSV was comparable to influenza 💡RSV may be an important contributor to long-term cardiovascular morbidity — highlighting the importance of prevention and vaccination. Full study link: jamanetwork.com/journals/jam… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes

🫁 What do B-lines on lung ultrasound mean in hospitalized COVID-19 patients? A new study by Øyvind Johannessen, @pmyhre and colleagues from @CTCPR_, published in @Frontiers in Cardiovascular Medicine, examined 270 non-ICU COVID-19 patients using 8-zone lung ultrasound a median of 4 days after admission. Key insights 👇 ✔️ B-lines were almost universal (97%) ✔️ Associated with inflammation and severity • Higher CRP • Higher Early Warning Score • Higher pulmonary pressure (TR gradient) ❌Not linked to left heart function or NT-proBNP ❌Not associated with 30-day mortality 💡In COVID-19, B-lines reflect inflammation and pulmonary stress—not left-sided heart failure. Full study link: frontiersin.org/journals/car… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @fdavidovski_MD @Espersen_C @niklasdj1 @AnneBjergn @JakobOeystein @MortenSengelov

🫀How much of the cardiac risk in psoriasis patients with MASLD is driven by the liver disease itself — and how much by underlying cardiometabolic risk factors? New study by @dons_maria and colleagues from @CTCPR_, published in @JInternMed, examined cardiac structure/function and MASLD in 255 adults with psoriasis. Key findings 👇 ✔️MASLD was linked to worse cardiac function and adverse cardiometabolic profiles ✔️After adjustment, BMI and diabetes were independently associated with myocardial dysfunction 💡Highlights the importance of cardiometabolic risk factor control in psoriasis patients with MASLD. Full study: onlinelibrary.wiley.com/doi/… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @fdavidovski_MD @KristofferSkaar @AM_reimer @MortenSengelov

🫀Can advanced strain imaging improve risk stratification after CABG? New study by @fdavidovski_MD and colleagues from @CTCPR_, published in the International Journal of Cardiovascular Imaging, examined layer-specific GLS in 641 CABG patients using speckle-tracking echocardiography. Key findings 👇 ✔️Reduced GLS across all myocardial layers was linked to higher mortality ✔️Epicardial GLS remained independently prognostic even after EuroSCORE II adjustment ✔️Layer-specific GLS was associated with HF/CV death outcomes 💡Advanced echocardiographic strain imaging may add important prognostic value after cardiac surgery. Study link: link.springer.com/article/10… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @matslassen @KristofferSkaar @Espersen_C @MortenSengelov @fwemmer1

🎓Congratulations to our newest PhD, @matslassen! On Friday (15/05/26), Mats successfully defended his PhD thesis titled: "Effect of Respiratory Syncytial Virus Vaccination on Cardiorespiratory Hospitalizations - From observational data to randomized evidence: Insights from a registry-based cohort study and a pragmatic randomized clinical trial” Mats's PhD focused on RSV, cardiovascular disease, and pragmatic clinical trials, with a particular focus on the DAN-RSV trial - a large-scale pragmatic randomized trial embedded within the Danish nationwide digital health infrastructure. An impressive milestone driven by collaboration and dedication. Congratulations from all of us at @CTCPR_ 👏 @TorBiering @UCPH_health @CopCard @RigsHeart @HGHHjerte @Stenodiabetes

🚨Clinical Assistant wanted at @CTCPR_ , Gentofte Hospital 1-year position (PhD option) Work includes: • Clinical trials & RCTs • Patient inclusion & clinical work • Data, analysis & manuscripts • Conferences & research MD with interest in cardiology & research. 📩Apply here: regionh.dk/job/søg-job/… @TorBiering @Stenodiabetes @CopCard @Rigshospitalet @HGHHjerte @HerlevGentofte

🚨 We’re hiring: Postdoc / Senior Researcher in Cardiovascular Research MD with PhD (or PhD track)? Strong in CV research, trials & epidemiology? Join @CTCPR_ , Gentofte Hospital—an internationally recognized center working with clinical studies, registry research & large-scale RCTs. We’re looking for experience in: • Cardiovascular medicine & clinical research • Clinical trials (RCTs/pragmatic designs) • Stats & study design (R / Stata / SAS) • Registry/epidemiology research • CV imaging (echo = plus) • Scientific writing & publications Work closely with clinicians, statisticians, PhD students & international collaborators in a high-impact, ambitious environment. 📩Full details & application: regionh.dk/job/søg-job/… @TorBiering @Stenodiabetes @CopCard @Rigshospitalet @HGHHjerte @HerlevGentofte

🚨We’re hiring: Data Manager / Biostatistician at @CTCPR_ Join our cardiovascular research team at Gentofte Hospital working with: • Danish national health registries • Large-scale randomized clinical trials • Statistical analyses & data management • Real-world cardiovascular research Open positions: 🔹1-year Data Manager/Biostatistician 🔹3-year Biostatistician Looking for candidates with experience or interest in: 📊Statistics / epidemiology 💻SAS, R, Python, Stata etc. 📑Registry & clinical research Full job posting below 👇 regionh.dk/job/søg-job/… @TorBiering @Stenodiabetes @CopCard @Rigshospitalet @HGHHjerte @HerlevGentofte

🫀Are patients with atrial fibrillation better protected with high-dose influenza vaccines? New study by @Espersen_C & @CTCPR_ (@ACCinTouch) using DANFLU-2: - n=332,438 adults ≥65 years - 34,085 (10.3%) with AF - Randomized to high-dose vs standard-dose influenza vaccine across 3 seasons 🔑Key findings: AF patients had markedly higher risks of influenza-related & cardiovascular hospitalizations High-dose vaccine ↓ hospitalizations for: - Cardiorespiratory disease - Influenza (incl. lab-confirmed) - Cardiovascular disease Effects consistent regardless of AF status Greater absolute benefit in AF (NNV ~243 vs ~933 in non-AF) Worth noting: The trial was not powered for the AF subgroup analyses, meaning these findings should be considered hypothesis-generating. Implication: In high-risk populations like AF, vaccine choice—not just vaccination—may matter 🫀 📄 Study link: sciencedirect.com/science/ar… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @RebeccaCHarris @matslassen @KristofferSkaar @niklasdj1 @AM_reimer @dons_maria @KBernholm @fdavidovski_MD @LisaSteenDuus @camillaiottosen @AnneBjergn @drJBorchsenius @katjabartholdy @AdamLanghoff @MortenSengelov

🫀Are CKD patients underprotected during flu season? New study by @katjabartholdy & colleagues from @CTCPR_ using DANFLU-2 (n=332,438; 14% CKD) has been published in the journal of @ACCinTouch Key findings: • HD vaccine ↓ flu/pneumonia hosp. by 16.9% in CKD (vs 0.6%) • ↓ influenza hosp. by 68.6% in CKD • Cardiorespiratory benefits consistent across groups Important context: The trial was not powered for the CKD subgroup analyses, so these findings should be considered hypothesis-generating. Implication: Vaccine choice may matter most in high-risk patients🫀 Full study: sciencedirect.com/science/ar… @TorBiering @CopCard @RigsHeart @HGHHjerte @Stenodiabetes @RebeccaCHarris @matslassen @KristofferSkaar @niklasdj1 @AM_reimer @dons_maria @KBernholm @fdavidovski_MD @LisaSteenDuus @camillaiottosen @AnneBjergn @drJBorchsenius @Espersen_C @AdamLanghoff @MortenSengelov