Computational biologist interested in cancer evolution, maths modelling and Bayesian stats. Junior group leader at @ImperialImmuno
Joined November 2010
- Tweets 799
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- Followers 416
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61 Photos and videos
Pinned Tweet
10 Sep 2025
Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @Nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7, link below)
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Calum Gabbutt retweeted
Jun 9
Recently completed your MSc in Bioinformatics? Mathematics postgrad wishing to gain experience of medical research? Looking for a PhD in computational biology? Consider applying for the fully funded position with me at @UniofReading:
jobs.ac.uk/job/DRV004/phd-st…
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May 14
How do epithelial stem cells in our intestine evolve over our lifetime?
In our new pre-print, @PBousquets and team used fluctuating methylation barcodes to find out!
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May 14
PHYFUM is therefore a low-cost method to uncover evolution of healthy glandular tissues, and we hope to use the method to develop evolutionary biomarkers of neoplastic progression.
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Mar 20
If you're interested in integrating theory and data to better understand how cancers evolve, register for the 2nd CANPOP meeting!
Featuring a keynote talk from Martin Taylor (@mst_paralogue) and a series of selected short talks, what better way to spend a Monday afternoon?
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Mar 20
Registration is free: forms.gle/jSxB1TdPURRaBH8K7
To submit an abstract for a short presentation, please enter it during the registration process and submit by Fri 10th April at 5pm. Registration will remain open after the 10th, but abstracts will no longer be accepted.
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Calum Gabbutt retweeted
Feb 24
In 1999, Tom Maniatis discovered something remarkable: neurons achieve self-avoidance via stochastic methylation of the protocadherin gene cluster.
We've just discovered this locus is an evolvable in-vivo barcode across the human tissues: biorxiv.org/cgi/content/shor… 🧵
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Feb 13
If you’re interested in machine learning and mathematical modelling, we’re recruiting a PhD student to develop new methods for studying cancer evolution at @ImperialImmuno.
Link below.
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Feb 13
An incredible opportunity for early career researchers - Imperial's Faculty of Medicine is hiring 20 Assistant Professors!
We're #hiring new non‑clinical Assistant Professors at @ImperialMed!
Want to join us at @ImperialImmuno?
Make sure to choose ‘Immunology and Inflammation’ as your first preference when applying.
✍️Apply by 11 March 2026.
imperial.ac.uk/jobs/search-j…
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10 Sep 2025
Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @Nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7, link below)
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10 Sep 2025
Finally, fCpGs record clonal dynamics over time. In two patients with Richter transformation (RT), the emergence of an altered phenotype with dismal outcomes, we inferred that the RT clone diverged from the non-RT lineage over 30 years prior to its clinical manifestation! (6/7)
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10 Sep 2025
This was a massively collaborative project and it was a pleasure to work with such amazing researchers, but particular thanks to @Marti_DF, @BEpigenomics and @trevoragraham. (7/7)
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