Joined September 2013
- Tweets 1,175
- Following 3
- Followers 321
- Likes 13
36 Photos and videos
20 Dec 2025
What's really going on with flu this winter? - BBC News share.google/w79NNdVt8oP3bNF…
12
30 May 2025
Antigenic drift with changing dominant strains is expected for SARS-COV-2, just like influenza or other ENDEMIC respiratory viruses showing repeated reinfections.
NB.1.8.1 (an XDV sublineage) caused only a minor wave compatible with time-relared waning herd immunity in Hong Kong.
188
15 May 2025
Low natural circulation after last summer likely accounts for current Covid wave in Hong Kong. Covid naive infants at risk after maternal antibodies drop. XDV NOT new: in China since last year. Viral strains diversify across the globe: antigenic drift driven by herd immunity.
115
23 Aug 2024
Vaccination Paradox:
Vaccination alone NEVER rapid enough to stop any brewing pandemic. CONTAINMENT at outbreak sites, esp in Africa, is the key for Mpox clade 1b at this stage. Prepare for but NOT rely on MASSIVE vaccination: LITTLE financial incentives before actual pandemic.
11 Jun 2022
Intensified case finding among those with s/s or risk factors is the first & key step in monkey pox containment. Detecting cases without identifiable sources allow initiation of isolation & quarantine. Only secondary spread reflects delay / failure of control.
1
2
165
23 Aug 2024
As predicted, the minor Covid-19 rebound peaked at week 31 in Hong Kong well before the FliRT variants became predominant: WANING IMMUNITY causes the rebound in seasonal fluctuation. Antigenic drift is RESULT of selection pressure from herd immunity vs old dominant strains.
11 Aug 2024
Cyclical fluctuation of Covid-19 in Hong Kong: The recent Covid-19 rebound is minor c.f. past waves. It is peaking as the total number and sewage level have begun to drop.
1
634
11 Aug 2024
Cyclical fluctuation of Covid-19 in Hong Kong: The recent Covid-19 rebound is minor c.f. past waves. It is peaking as the total number and sewage level have begun to drop.
347
24 May 2024
The H1 flu wave has just peaked.
16 May 2024
1
2
130
30 May 2024
The H1 flu wave coming down without rise in H3 or flu B in Hong Kong. This could be an early onset summer wave. Cross immunity from preceding bi-peak H3 wave & personal hygiene: low H1 peak but likely higher trough (needed to top up herd immunity) where vulnerable still at risk.
1
65
16 May 2024
16 May 2024
The H1N1 wave in Hong Kong could well be peaking
199
9 May 2024
A distinct H1 flu wave after a wide & distorted H3 flu wave in Hong Kong. Postpandemic flu waves were lower but protracted c.f. prepandemic ones. Severe cases in young children, often with encephalopathy, esp among unvaccinated.
2
2
3
597
30 Apr 2024
nature.com/articles/d41586-0…
Undetected spreading in cattle herds is a danger sign, giving time for H5N1 to adapt & jump through multiple human contacts.
Need to see how best to detect and control such outbreak EARLY, just like for poultry & pigs.
133
Chi C LEUNG retweeted
25 Apr 2024
Flu rebounds due to H1 strains in HK.
Postpandemic flu waves have so far been LOW but PROTRACTED, c.f. prepandemic: Residual personal protective measures slow buildup of herd immunity thru virus spread??
Low or high, the vulnerable, esp children & elderly remain at risk.
1
82
21 Apr 2024
Minor rebound of flu due to H1 strains on Hong Kong. With the well-matched current season flu vaccines and hotter weather, the H1 rebound is likely going to be mild. Unvaccinated young kids at risk: past flu and 2022/2023 flu vaccines may not protect vs current H1 strains.
2
192
25 Apr 2024
Flu rebounds due to H1 strains in HK.
Postpandemic flu waves have so far been LOW but PROTRACTED, c.f. prepandemic: Residual personal protective measures slow buildup of herd immunity thru virus spread??
Low or high, the vulnerable, esp children & elderly remain at risk.
1
82
14 Mar 2024
Use of spirometry to detect airflow obstruction - Leung - Respirology - Wiley Online Library onlinelibrary.wiley.com/doi/…
68
Chi C LEUNG retweeted
14 Mar 2024
🌏Respirology
Use of #spirometry to detect airflow obstruction- an expert view on the topic in #Respirology
#FreeAccess
onlinelibrary.wiley.com/doi/…
@CclLeung
12
30
1,967
12 Jan 2024
thelancet.com/journals/eclin…
We have been looking for that for influenza for years.
Paradox: for a virus to survive in host during evolution, it's conserved parts must have other ways of evading host immunity.
Waning immunity is another separate issue to overcome.
1
429
Chi C LEUNG retweeted
20 Dec 2023
JN.1 is increasing but < 2×/wk. If R0~10, serial interval~3.5D (like other omicrons): R/R0<15% or 85% population still immune & only 5% more of population infected will drive R below 1.
Major wave NOT expected.
By the way, case rates in Singapore and USA appear stabilising.
2
1
303
Chi C LEUNG retweeted
1 Dec 2023
Successive omicron waves showed decreasing amplitudes. Both the spread under intensive global mixing and cross-immunity by XBB.1.5 vaccines may help to gauge the actual degree of immune escape of JN.1. Hopefully, we are not likely to see a major wave.
3
1
1
454