Official Twitter for Celixir World-Class #scientists and #biotechnology leadership is devoted to discovering breakthrough regenerative Stem Cell #medicines.
A fascinating read about a promising cell therapy for RPE (Retinal Pigment Epithelium) degeneration such as in age related macular degeneration.
nature.com/articles/s41598-0…
This interesting study looks at aiming to repair pathogenic allele-specific single-nucleotide mutations using a single round of genome editing.
nature.com/articles/s41598-0…
The European Medicines Agency (EMA) has agreed to review a request to approve the investigational CAR T-cell therapy, lisocabtagene maraleucel (liso-cel), for people with pretreated lymphomas.
immuno-oncologynews.com/2020…
CAR-T cells are promising for the treatment of cancer but their side effects are a concern. In this study, a team has developed a new CAR T-cell immunotherapy strategy that uses light to activate the immune cells specifically in cancerous regions.
immuno-oncologynews.com/2020…
3D printing allows the formation of a working heart pump from human heart cells and is another step towards artificial hearts. sciencedaily.com/releases/20…
This study shows the safety and efficacy of dopaminergic progenitors (DAPs) derived from a clinical-grade human iPSC line. These cells have the potential to replace damaged neurons in Parkinson’s disease.
nature.com/articles/s41467-0…
This study identifies roles of autophagy in embryonic stem cell renewal and differentiation and presents an opportunity for new regenerative medicines.
regmednet.com/process-of-ste…
A nice summary of terminology relating to advanced therapy medicinal products (ATMPs), including gene and cell-based therapies, tissue-engineered products, and combined ATMPs.
raps.org/news-and-articles/n…
The U.S. Food and Drug Administration (FDA) restarting on-site inspections based on a COVID-19 Advisory Rating system (COVID-19 Advisory Level).
gmp-compliance.org/gmp-news/…
The Medicines and Healthcare products Regulatory Agency (MHRA) is making careful preparations for a safe return to normal UK on-site Good Practice (GxP) inspection scheduling.
mhrainspectorate.blog.gov.uk…