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Cell Genomics @CellGenomics

Cell Genomics is a new gold #OpenAccess and #OpenScience research journal that represents the forefront of #genetics and #genomics 🧬

Joined June 2020
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Cell Genomics@CellGenomics
22 Sep 2022
Meet with us to discuss your research or to learn more about the publishing process! hubs.li/Q01msqBt0
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Duplicate, diversify, repeat: The evolution of NOTCH2NL dlvr.it/TT1LxQ

Duplicate, diversify, repeat: The evolution of NOTCH2NL

Segmental duplications are key drivers of evolutionary innovation but are also particularly challenging to study. In this issue, Real et al. resolve the genetic diversity, structural history, and...

cell.com
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Meet the author: Jiarui Ding dlvr.it/TT1DQh

Meet the author: Jiarui Ding

In this issue of Cell Genomics, Dr. Jiarui Ding presents his paper, “ProtoCloud: A prototypical self-explaining model for single-cell analysis.” Dr. Ding is an assistant professor in Computer Science...

cell.com
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Causal effect estimation from trans-regulatory single-cell CRISPR screens dlvr.it/TT128x

Causal effect estimation from trans-regulatory single-cell CRISPR screens

This minireview outlines how single-cell CRISPR screens can be used to estimate causal effects of genetic perturbations on gene expression. Christensen et al. explain the key assumptions required for...

cell.com
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Toward telomere-to-telomere genomics in Fabaceae: Unlocking comparative and functional insights into symbiotic nitrogen fixation dlvr.it/TT0wkr

Toward telomere-to-telomere genomics in Fabaceae: Unlocking comparative and functional insights...

Shi et al. argue that telomere-to-telomere genome assemblies across a diverse range of legume species are essential to uncover the genetic and epigenetic basis of symbiotic nitrogen fixation. Such...

cell.com
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A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases dlvr.it/TT0R5N

A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of...

Cox et al. reconstruct the ancient network of protein interactions from the last eukaryotic common ancestor. These deeply conserved protein complexes are often critical to modern cells and suggest...

cell.com
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Synthetic rewriting of the IGH locus dlvr.it/TT0HGf

Synthetic rewriting of the IGH locus

Fu et al. create a de novo-designed synthetic human immunoglobulin heavy chain locus in mice and show that programmable locus shuffling expands V(D)J recombination diversity, establishing a general...

cell.com
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FastGxC: Fast and powerful context-specific eQTL mapping in bulk and single-cell data dlvr.it/TT04JQ

FastGxC: Fast and powerful context-specific eQTL mapping in bulk and single-cell data

Krockenberger, Lu, et al. introduce FastGxC, a method that identifies how genetic variants regulate gene activity in specific tissues and cell types more efficiently than existing approaches. Applied...

cell.com
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Regulatory network topology and the genetic architecture of gene expression dlvr.it/TSzyYr

Regulatory network topology and the genetic architecture of gene expression

Aguirre et al. describe a model of gene regulatory networks and show how their properties shape the distribution of genetic effects on gene expression. Their results imply constraints on real network...

cell.com
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Interferon-related inflammaging links epigenetic age acceleration to multimorbidity dlvr.it/TSzSlh

Interferon-related inflammaging links epigenetic age acceleration to multimorbidity

Liu et al. investigated the relationship between two hallmarks of aging (chronic inflammation and DNA methylation alterations) in four independent cohorts covering different ages and health conditi...

cell.com
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ProtoCloud: A prototypical self-explaining model for single-cell analysis dlvr.it/TSzKRP

ProtoCloud: A prototypical self-explaining model for single-cell analysis

Guo et al. introduce ProtoCloud, a deep learning model for cell type annotation of individual cells. By embedding cells around prototypes, the model enables transparent classification, identifies...

cell.com
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Abstract deadline approaching for @CellPressEvents #CPSsinglecellbiology2026 Munich | Dec 2–4, 2026 | @HelmholtzMunich AI, multi-omics, spatial biology & more. Deadline: July 17, 2026 Selected abstracts considered for talks & posters.
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CellBouncer, a unified toolkit for single-cell demultiplexing and ambient RNA analysis, reveals hominid mitochondrial incompatibilities dlvr.it/TSz6XW

CellBouncer, a unified toolkit for single-cell demultiplexing and ambient RNA analysis, reveals...

Schaefer et al. introduce a new bioinformatic toolkit for pooled single-cell sequencing experiments, which increases throughput and mitigates batch effects and biases. This includes a method for...

cell.com
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Separating direct, indirect, and parent-of-origin genetic effects in the human population dlvr.it/TSy7ln

Separating direct, indirect, and parent-of-origin genetic effects in the human population

Krätschmer et al. develop a novel statistical approach to distinguish between direct genetic effects (DGE), indirect genetic effects (IGE) (how parental DNA shapes the child’s environment), and...

cell.com
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Genomic and socioeconomic drivers of antimicrobial resistance forecast to 2050 dlvr.it/TSs3yV

Genomic and socioeconomic drivers of antimicrobial resistance forecast to 2050

Antimicrobial resistance is an escalating global threat, yet its biological and social determinants remain poorly understood. Baker et al. used machine learning integrating global genomics, resista...

cell.com
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A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases dlvr.it/TSlDlt

A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of...

Cox et al. reconstruct the ancient network of protein interactions from the last eukaryotic common ancestor. These deeply conserved protein complexes are often critical to modern cells and suggest...

cell.com
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Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations by @Jtenthorey and colleagues hubs.li/Q04fYF-Z0 Highlight from @CellGenomics
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Laura is an evolutionary geneticist, with interests that range across the fields of genetics and genomics research. Get to know more Cell Genomics editors: hubs.li/Q047-RhD0
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Proteome-wide assessment of differential missense variant clustering in neurodevelopmental disorders and cancer by Jeffrey K. Ng (@WashUGenetics) et al. hubs.li/Q04fYVWq0 Highlight from @CellGenomics
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Synthetic rewriting of the IGH locus dlvr.it/TSbtW7

Synthetic rewriting of the IGH locus

Fu et al. create a de novo-designed synthetic human immunoglobulin heavy chain locus in mice and show that programmable locus shuffling expands V(D)J recombination diversity, establishing a general...

cell.com
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FastGxC: Fast and powerful context-specific eQTL mapping in bulk and single-cell data dlvr.it/TSbgrB

FastGxC: Fast and powerful context-specific eQTL mapping in bulk and single-cell data

Krockenberger, Lu, et al. introduce FastGxC, a method that identifies how genetic variants regulate gene activity in specific tissues and cell types more efficiently than existing approaches. Applied...

cell.com
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