@CellRepMed profile picture
Cell Reports Medicine @CellRepMed

Broad-scope #OA journal from @CellPressNews publishing cutting-edge science across the spectrum of #Translational and #ClinicalResearch | Editor: @DrSaraHam

Joined October 2019
  • Tweets 2,801
  • Following 356
  • Followers 18,955
243 Photos and videos
Pinned Tweet
Cell Reports Medicine@CellRepMed
Feb 19
The new issue is out! Cover: Li et al. shows unsafe drinking water is linked to multiple health risks globally. The cover image—an auction for "the last glass of pure water"—highlights urgent need for policy action to reduce water-related disease. Follow us on LinkedIn for more!
1
5
1,280
Online now: Emerging therapeutic strategies for mitochondrial DNA-related diseases dlvr.it/TT2Jvl

Emerging therapeutic strategies for mitochondrial DNA-related diseases

In this review, Shi et al. discuss emerging therapeutic strategies for mitochondrial DNA-related primary mitochondrial diseases, including gene editing, pharmacological modulation of heteroplasmy,...

cell.com
1
132
Online now: Comprehensive mapping of human CD4 T cell epitopes for Nipah and measles as prototype Paramyxoviruses dlvr.it/TT1wMV

Comprehensive mapping of human CD4 T cell epitopes for Nipah and measles as prototype Paramyxovi...

Tarke et al. systematically map CD4 T cell epitopes in measles and Nipah viruses, revealing broad and overlapping immune targets. They define conserved T cell epitope regions (CTERs) that drive...

cell.com
325
Online now: Patient-derived organoids from metastatic colorectal cancer mirror tumor heterogeneity and predict patient survival and drug sensitivity dlvr.it/TT1jv1

Patient-derived organoids from metastatic colorectal cancer mirror tumor heterogeneity and predict...

Kryeziu et al. establish a living biobank of patient-derived organoids from metastatic colorectal cancer that models spatial and longitudinal tumor heterogeneity across molecular, morphological, and...

cell.com
3
7
428
Online now: Druggable β-catenin palmitoyl-switch coordinates immune evasion via immunogenic ferroptosis resistance and PD-L1-mediated immunosuppression dlvr.it/TT0y2p

Druggable β-catenin palmitoyl-switch coordinates immune evasion via immunogenic ferroptosis...

Zhang et al. identify a druggable palmitoylation switch on β-catenin at C466, mediated by ZDHHC5, which displaces inhibitory S-nitrosylation. This switch coordinates immune evasion in colorectal...

cell.com
1
2
330
Online now: Intravenous human umbilical cord-derived mesenchymal stem cell transplantation for ischemic stroke (MERIT): A phase 1 trial dlvr.it/TSzy1b

Intravenous human umbilical cord-derived mesenchymal stem cell transplantation for ischemic stroke...

Umbilical cord derived-mesenchymal stem cell (UC-MSC) transplantation is a promising therapy for ischemic stroke. Cui et al. report the results of a phase 1 clinical trial that enrolled 18 patients...

cell.com
1
209
Online now: Pro/synbiotics reduce systemic inflammation and improve gut health in Kenyan infants: An open label, randomized, 4-arm, phase II trial dlvr.it/TSzM55

Pro/synbiotics reduce systemic inflammation and improve gut health in Kenyan infants: An open...

In this open-label, randomized trial in 600 vulnerable infants in western Kenya, Otiti et al. find that chronic systemic inflammation occurs at age 6 months in 43% controls but in <3% of infants...

cell.com
1
3
206
Online now: Gut microbiome composition and functional potential associate with incident type 2 diabetes in 4,685 adults from a Swedish prospective cohort dlvr.it/TSz4Sn

Gut microbiome composition and functional potential associate with incident type 2 diabetes in...

Toubon et al. show that the gut microbiome measured years before diagnosis predicts future type 2 diabetes risk. Using a large prospective Swedish cohort of 4,685 adults, they identify specific...

cell.com
209
Online now: CSNK2B gene replacement rescues autism-related phenotypes and establishes translational EEG biomarkers dlvr.it/TSyNK7

CSNK2B gene replacement rescues autism-related phenotypes and establishes translational EEG...

Ding et al. show that Csnk2b haploinsufficient mice recapitulate autism- and epilepsy-related phenotypes. Early postnatal gene replacement rescues these deficits and restores noninvasive EEG biomar...

cell.com
1
2
243
Online now: Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppression dlvr.it/TSy60Y

Fungal metabolite-based immunotherapy overcomes tumor-associated macrophage immunosuppression

Hu et al. discover a fungal metabolite, IM502, that re-educates immunosuppressive cells inside tumors. By reprogramming macrophages, IM502 potently activates anti-tumor immunity, suppresses cancer...

cell.com
3
7
455
A reminder to submit your abstract before June 19, 2026 for a chance to join our keynote speakers @dixitvishva, Douglas Green, & @WuLabHarvard October 22–24, 2026, Hangzhou, China   Submit here: 👉hubs.li/Q04kGYRP0 @CellPressEvents #CSCellDeath26
2
308
Online now: An international multidisciplinary consensus statement on laparoscopic liver biopsy dlvr.it/TSxQv5

An international multidisciplinary consensus statement on laparoscopic liver biopsy

Si-Yi Lei et al. present an international consensus for laparoscopic liver biopsy. This consensus standardizes clinical practice and supports safe, accurate liver tissue acquisition to aid clinical...

cell.com
285
Online now: Elevating sleep to a global health priority: The One Sleep Health framework dlvr.it/TSx5rN

Elevating sleep to a global health priority: The One Sleep Health framework

Sleep health is increasingly disrupted by physical, social, and lifestyle factors across species, revealing shared vulnerabilities within ecosystems. Tahmasian et al. introduce the One Sleep Health...

cell.com
1
1
196
Online now: Lung mucosal and systemic responses at single-cell resolution in an aerosolized Mycobacterium bovis BCG human challenge model dlvr.it/TSwXbH

Lung mucosal and systemic responses at single-cell resolution in an aerosolized Mycobacterium bovis...

Li et al. show that aerosolized BCG challenge in BCG-naive volunteers recapitulates TB-specific cellular and transcriptional changes and expands predominantly pre-existing TCR clones, whose lung...

cell.com
4
7
646
Online now: The proteomics and phosphoproteomics landscape of melanoma under T cell attack dlvr.it/TSwLHm

The proteomics and phosphoproteomics landscape of melanoma under T cell attack

Franciosa et al. map the complex protein signaling between patient-derived melanoma and autologous T cells during active tumor attack. By analyzing these interactions without separating the cells,...

cell.com
1
1
437
Online now: Biomarker study of pembrolizumab in patients with advanced rare cancers dlvr.it/TSvxTr

Biomarker study of pembrolizumab in patients with advanced rare cancers

Naing et al. study pembrolizumab in advanced rare cancers and show that immune contexture, rather than genomic biomarkers alone, associates with clinical benefit, with responses enriched by MSI-H/T...

cell.com
2
2
544
Online now: Nanoparticle-based serine replenishment rescues SP1-BNIP3 mitophagy and ameliorates preeclampsia in preclinical models dlvr.it/TSvkcM

Nanoparticle-based serine replenishment rescues SP1-BNIP3 mitophagy and ameliorates preeclampsia in...

Wang et al. demonstrate that placental serine deficiency impairs SP1-BNIP3-mediated mitophagy, triggering detrimental ROS accumulation and PE progression. Notably, their nanoparticle-based serine...

cell.com
283
Online now: Circulating cell-free mtDNA fragmentomics for early detection of gastric cancer and precancerous lesions dlvr.it/TStwGK

Circulating cell-free mtDNA fragmentomics for early detection of gastric cancer and precancerous...

Dang et al. develop a ccf-mtDNA fragmentomics-based blood test for gastric cancer detection. This non-invasive approach achieves high accuracy in identifying early cancer and precancerous lesions,...

cell.com
250
Online now: Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows regeneration via mitochondrial uncoupling dlvr.it/TSswcB

Transcriptome-guided development of a fibrosis-reversal compound reduces skin scarring and allows...

Given the lack of effective treatments for pathological scarring, Chen et al. present a fibrosis-reversal compound (FR-1) discovered through transcriptome-guided drug discovery. By mitochondrial...

cell.com
1
4
421
Online now: Hearing aid effectiveness and probable dementia risk across 33 countries: A pooled analysis of seven cohorts dlvr.it/TSsJmM

Hearing aid effectiveness and probable dementia risk across 33 countries: A pooled analysis of...

Jiang et al. pool data from 61,089 hearing-impaired older adults in 33 countries. They find that effective hearing aid use, but not poor use, is linked to reduced probable dementia risk. The associ...

cell.com
1
231
Online now: Predicting glioma survival and extracellular matrix remodeling through MRI radiogenomics dlvr.it/TSs1qF

Predicting glioma survival and extracellular matrix remodeling through MRI radiogenomics

Bie et al. develop an MRI-based radiomics signature that non-invasively assesses extracellular matrix remodeling in glioma, predicts patient survival, and identifies MMP2 as a key therapeutic target....

cell.com
326
Load more