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Cell Reports @CellReports

Cell Reports is an open-access journal at Cell Press, publishing weekly. Tweets by Cell Reports editors.

Joined July 2011
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2,018 Photos and videos
Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H2O2-mediated kinase oxidation dlvr.it/TT1M3d

Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H2O2-mediated...

Kostas et al. show that elevated inorganic phosphate induces a mitochondria-derived hydrogen peroxide burst that triggers activation of FGFR1 via oxidation of key residues in the kinase domain. This...

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Cisplatin resistance in an ovarian cancer model is mediated by microtubule dynamics regulator TPPP3 in synergy with tubulin code rewiring dlvr.it/TT1Gqc

Cisplatin resistance in an ovarian cancer model is mediated by microtubule dynamics regulator TPPP3...

Horibata et al. show that the cancer drug cisplatin destabilizes microtubules by accelerating loss of the GTP cap and identify tubulin polymerization-promoting protein 3 (TPPP3) as a microtubule...

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Aging restricts maturation of CXCL13 T follicular helper cells in human immunity dlvr.it/TT1DZ1

Aging restricts maturation of CXCL13 T follicular helper cells in human immunity

Bracey et al. show that impaired antibody responses with age are primarily driven by defective T follicular helper cell maturation rather than intrinsic B cell dysfunction. They identify loss of...

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A conserved antioxidant defense at the endoplasmic reticulum membrane dlvr.it/TT15cY

A conserved antioxidant defense at the endoplasmic reticulum membrane

Ji et al. identify ERGU-1/TMEM161B as an evolutionarily conserved ER-transmembrane protein that modulates oxidative stress generated during oxidative protein folding. This critical guardian maintains...

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Socially shared emotions shape the activity of the medial prefrontal cortex during inference of others’ emotional states dlvr.it/TT10g3

Socially shared emotions shape the activity of the medial prefrontal cortex during inference of...

People differ in how they interpret social situations and infer others’ emotions. This fMRI study shows that the medial prefrontal cortex integrates this social variability to infer others’ emotional...

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KRAS4A promotes oligomerization of hexokinase 1 on mitochondria dlvr.it/TT0xY0

KRAS4A promotes oligomerization of hexokinase 1 on mitochondria

Hexokinase 1 (HK1) associates with the outer mitochondrial membrane (OMM) where its allosteric regulation depends on oligomerization. KRAS4A interacts with HK1 on the OMM and enhances its catalytic...

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A progenitor cell population contributes to prenatal injury repair and neonatal antimicrobial defense in the small intestine dlvr.it/TT0sdw

A progenitor cell population contributes to prenatal injury repair and neonatal antimicrobial...

Shen et al. report a population of small intestinal sentinel progenitor cells (SISPCs), marked by Lysozyme1 in the embryonic and neonatal mouse small intestine. SISPCs display stemness potential in...

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Nerve-proximal tertiary lymphoid structures predict chemotherapy sensitivity in pancreatic cancer dlvr.it/TT0RDS

Nerve-proximal tertiary lymphoid structures predict chemotherapy sensitivity in pancreatic cancer

Cai et al. investigate how neural remodeling shapes antitumor immunity following neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma. They find that chemotherapy induces Schwann cell...

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Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brain dlvr.it/TT0L48

Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function...

Shah et al. spatially characterize the agranular human dACC through integration of paired spatial transcriptomics and snRNA-seq data from ten neurotypical control donors, specifically focused on...

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nsP3-FXR co-condensation enables alphavirus replication and reveals a targetable alphavirus vulnerability dlvr.it/TT0HRQ

nsP3-FXR co-condensation enables alphavirus replication and reveals a targetable alphavirus...

Xie and Cao et al. show that nsP3-FXR condensation is crucial for VEEV replication. UBAP2L is identified as a nsP3-FRX condensate-resident restriction factor that suppresses VEEV replication....

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There's still time to submit your abstract for the @CellPressEvents #CSAging2026, taking place Oct. 4–6, in Seville, Spain. Join leading researchers exploring the mechanisms of aging, healthspan & resilience, including keynote Luigi Ferrucci (@NIHAging). hubs.li/Q04l4LKb0
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Circuit organization and transcriptomic heterogeneity of sympathetic circuits innervating cranial structures dlvr.it/TT082V

Circuit organization and transcriptomic heterogeneity of sympathetic circuits innervating cranial...

Senturk et al. map the molecular and anatomical organization of superior cervical ganglion neurons targeting cranial structures mediating facial emotions. Individual neurons project to a single...

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NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis infection dlvr.it/TT02dT

NRF2-mediated inhibition of alveolar macrophage MHC II expression during Mycobacterium tuberculosis...

Pham et al. show that, during Mycobacterium tuberculosis infection, NRF2 activation in alveolar macrophages inhibits MHC II but not MHC I, leading to dampening of antigen presentation and CD4 T cell...

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Spatial and temporal single cell multi-omics in mice reveals macrophage-SFRP4 stroma interactions promoting endometrial regeneration via TNF-α dlvr.it/TSzzHS

Spatial and temporal single cell multi-omics in mice reveals macrophage-SFRP4 stroma interactions...

Li et al. used a mouse model of endometrial injury to reveal crosstalk between early stage injury macrophages and SFRP4 stromal cells, and combined human datasets to prove the conserved regenerative...

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Chromosome-scale genomes of water lilies provide evolutionary insights into the aquatic adaptation of angiosperms dlvr.it/TSzvM8

Chromosome-scale genomes of water lilies provide evolutionary insights into the aquatic adaptation...

Chromosome-scale genomes of early-diverging water lilies reveal how whole-genome duplications and metabolic remodeling drove aquatic adaptation. This work illuminates the genomic innovations underl...

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Heterologous betacoronavirus spike immunization in non-human primates elicits antibodies that neutralize both sarbeco- and merbecoviruses dlvr.it/TSzSvq

Heterologous betacoronavirus spike immunization in non-human primates elicits antibodies that...

Broad coronavirus vaccines are needed to address current SARS-CoV-2 variants and future spillovers. Dueker et al. show that heterologous β-coronavirus spike immunization in rhesus macaques targets...

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Not long before we welcome the mitochondrial community to the historic city of Glasgow, where we'll explore the latest advances in the field, reconnect with colleagues and friends, and forge new collaborations. View the program and register: hubs.li/Q04kN-QX0 #CSMito2026
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PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer dlvr.it/TSzNFT

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer

(Cell Reports 22, 2469–2481; February 27, 2018)

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Synchronous spatiotemporal control of autophagy and organelle trafficking is necessary for infection by Magnaporthe oryzae dlvr.it/TSzKb4

Synchronous spatiotemporal control of autophagy and organelle trafficking is necessary for infect...

The blast fungus forms a force-generating appressorium for plant infection. Eseola et al. show how individual spore cells adopt distinct fates, trafficking organelles to the appressorium or undergo...

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Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function alterations dlvr.it/TSzB9D

Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function...

This study establishes melPDomiX, a multi-omics resource of melanoma-patient-derived xenografts. By integrating genomic, transcriptomic, and proteomic datasets through factor analysis and structural...

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