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Charlie Lay @CharlieLay13

GSK iCASE PhD student in Pharmacology at the University of Nottingham

Joined February 2021
  • Tweets 4
  • Following 31
  • Followers 47
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Charlie Lay retweeted
Cell Press @CellPressNews
20 Feb 2022
Read this recent article from @SteveH025 @CharlieLay13 & others in @CellChemBiol "Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET" #BPS2022 hubs.li/Q014sp9d0

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric...

Lay et al. measure the binding of TAMRA-labeled IL-23 to NanoLuciferase fused receptor subunits, revealing a high-affinity binding site formed from a heteromer of IL23R and IL12Rβ1. NanoBRET was also...

cell.com
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I'm happy to share our new paper on the development of an intracellular assay for compound residence time. Thank you to all the scientists at GSK who helped with this especially Kelly Gatfield and Pete Craggs! authors.elsevier.com/a/1dknD…

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Charlie Lay retweeted
Cell Chemical Biology @CellChemBiol
13 Sep 2021
Online now! Development of an intracellular quantitative assay to measure compound binding kinetics dlvr.it/S7W2gt #chembiol
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Charlie Lay retweeted
Cell Chemical Biology @CellChemBiol
25 May 2021
Online now! Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET dlvr.it/S0Ng3f #chembiol
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