The Cunniff lab is interested in how mitochondrial dynamics influence cell processes and is identifying new therapeutics targets for aggressive cancers.
Joined July 2019
- Tweets 170
- Following 120
- Followers 147
- Likes 162
10 Photos and videos
10 Mar 2025
Congratulations to Dr. Nate Shannon on his recently published manuscript! Lots of exciting findings to follow up on related to Miro1 and mitochondrial positioning. journals.biologists.com/jcs/…
40
12 Dec 2024
Congrats to Nate on an excellent thesis!
Congrats Nathaniel Shannon, #UVMLarnerMed CMB graduate Ph.D. candidate, who successfully defended his dissertation, “The Role Of Miro1 Mediated Mitochondrial Positioning On Redox...” Pictured (left) w/ advisor @BrianCunniff, Ph.D.
@CunniffLab
@UVMResearch
@uvmcmb
@UVMGradCollege
1
2
116
21 Nov 2024
Come check out PhD candidate Victoria Gibson discuss the importance of Peroxiredoxin 3 in mesothelioma tumors at #SfRBM2024. SYMPOSIA SESSION 3: Unveiling the Therapeutic Potential: Exploring Redox Signaling from Fundamentals to Drug Targets 2:45pm @RedoxVT @RSOncologyLLC @SFRBM
1
4
118
7 Nov 2024
PhD Candidate Nate Shannon's first author paper out as a pre-print. Very proud of Nate! Some very interesting DEGs dependent on Miro1 expression and an interesting and evolving cell cycle/ERK1/2 story! @UVMcancercenter @RedoxVT #mitochondria
biorxiv.org/content/10.1101/…
1
1
4
119
Cunniff Lab retweeted
13 Jun 2024
NEW @NatureCellBio study finds glutathione S transferase theta drives pancreatic cancer metastasis by targeting fibronectin which places redox reactions front and center in tumor metastatic behavior.
Congrats @RedoxVT on supporting these findings!
go.nature.com/4aVXWAE
2
2
490
2 Jun 2024
Come chat at the booth, we have warm cookies!
2 Jun 2024
Meet us today June 2nd to hear Brian Cunniff, our CSO, talk about #mitochondrial dysfunction in cancer and how PRX3 plays a role. Booth #23094 #ASCO24 #cancerresearch @CunniffLab
2
3
209
29 May 2024
Excited to see Dean present exciting data around the Phase 1 trial of RSO-021 at #ASCO24. A redox-dependent cancer therapy currently being tested in Phase 2! @RedoxVT @UVMcancercenter @dean_fennell @RSOncologyLLC x.com/RSOncologyLLC/status/1…
1
2
472
Cunniff Lab retweeted
24 May 2024
#ASCO24 Abstracts have been published! See the short list of rapid oral abstracts in Developmental Therapeutics - Molecularly Targeted Agents & Tumor Biology and you will see our first-in-human phase 1 for RSO-021 @dean_fennell @CunniffLab @PRCLeicester
tinyurl.com/ASCO24
1
2
141
21 May 2024
Much deserved @dean_fennell !
21 May 2024
Congratulations @dean_fennell, very much deserved. You lead a great team, it’s a privilege to be part of it and a pleasure working alongside you.
le.ac.uk/news/2024/may/dean-…
72
1 May 2024
Congrats to @RSOncologyLLC for this much deserved recognition at #ASCO24 . Looking forward to @dean_fennell giving and exciting talk! @RedoxVT
1 May 2024
RSO-021 novel therapy and first-in-human clinical trial outcomes🫁will be presented on June 3rd at #ASCO24 with @dean_fennell #CancerResearch @BrianCunniff @UVMcancercenter
finance.yahoo.com/news/rs-on…
2
153
10 Apr 2024
Always an excellent meeting with great science and clinical progress being showcased! @RedoxVT @UVMcancercenter @RSOncologyLLC
9 Apr 2024
Sharing our 🔬scientific findings and preclinical data🫁. If you are at #AACR24 #SanDiego stop by today to see our presentation ~ @9am_today Titled: First-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 triggers mesenchymal-to-epithelial transition in #meso. #taketwo
1
7
194
18 Mar 2024
Looking forward to presenting our new data in support of the anti-cancer activity of RSO-021, lots of fresh discoveries! @RedoxVT @dean_fennell @UVMcancercenter
18 Mar 2024
Gearing up for #SanDiego next month. But you won't find us on the beach April 7th or 9th, since we will be presenting our posters at @AACR 2024. Add us to your itinerary to see our 🐭preclinical anticancer activity #Mesothelioma #CancerResearch @BrianCunniff @dean_fennell
2
113
Cunniff Lab retweeted
21 Feb 2024
Happy to announce our abstract has been approved 👏👏 #BTOG24 Our CSO Brian Cunniff, Phd, @CunniffLab will be presenting "First-in-class peroxiredoxin 3 (PRX3) inhibitors" poster. Stop by the welcome reception Wednesday April 17th, 18:30 – 20:00, say hello or ask questions.
1
4
118
Cunniff Lab retweeted
20 Feb 2024
Happy to share our review with @echouchani on recent advances in cysteine proteomics! @HarvardCellBio @DFCI_CancerBio
authors.elsevier.com/c/1idmT…
7
14
74
11,799
1 Feb 2024
Exciting news! @RedoxVT
1 Feb 2024
BIG NEWS! Groundbreaking anticancer drug moves to phase 2 expansion study @dean_fennell @CR_UK @STS_CTsurgery @asthmalunguk @LeicesterCTU
businesswire.com/news/home/2…
4
147
Cunniff Lab retweeted
26 Jan 2024
We are proud to announce we have 2 abstracts accepted for the @AACR Annual Meeting 2024 in San Diego. 👏 We will present our posters in session "Other Cellular Mechanisms for Anticancer Drug Action" and "Cellular Stress Responses 1"
See you in🌞SD! @CunniffLab @dean_fennell
1
6
173
Cunniff Lab retweeted
25 Jan 2024
Our team presenting our MITOPE phase 2 study of novel therapies for #mesothelioma and #lungcancer with malignant pleural effusions to #nurses at @HASAG education workshop in #London 👏
2
9
271
4 Dec 2023
PhD candidate Nate Shannon presenting his exciting data in which ERK1/2 activity is dysregulated in response to perinuclear mitochondrial clustering via Miro1 deletion. Great work, Nate!
4
124
1 Dec 2023
Come learn more about our work tomorrow at 1:00pm at #cellbio2023 in the Subgroup: Energy and Metabolism in Time and Space . See you in Boston!
2
103
8 Nov 2023
The Butler Family Foundation is raising money for mesothelioma research with an online auction of some very cool items/experiences. We are very grateful for their continued support! Get yourself some court-side Knicks tickets and support Meso research!
butlerfoundation.betterworld…
3
1
192