Group leader at @IMS_MRL researching insulin action and glucose transporter traffic.
Joined August 2009
- Tweets 445
- Following 679
- Followers 808
- Likes 2,590
13 Photos and videos
Pinned Tweet
14 Mar 2025
Please check out Liv's preprint and thread below!
14 Mar 2025
Very excited to finally share our work using subcellular proteomics to look at insulin-stimulated protein movement in adipocytes! 🧵below: (1/5)
biorxiv.org/content/10.1101/…
@DPhaz @IMS_MRL
3
4
23
3,369
Daniel Fazakerley retweeted
🧵How do cells coordinate what goes out with what comes in? We built Shape2Fate - a deep learning pipeline that tracks individual exocytic & endocytic events at ~100nm in live cells. What we found surprised us. 📄bioRxiv preprint: biorxiv.org/content/10.64898…
3
42
211
24,201
Daniel Fazakerley retweeted
Apr 2
📜Early preview of our new paper in Adv Science: ER shape matters for neuronal health - disrupting ER continuity halts neuro-firing as it slows Ca2 store refill, explaining selective neuronal vulnerability to ER problems in neurodegeneration 🧠
🧵later advanced.onlinelibrary.wiley…
6
23
890
Daniel Fazakerley retweeted
Jan 6
Our latest paper on cross-species effects of MC3R mutations is out: sciencedirect.com/science/ar…
1
2
98
Daniel Fazakerley retweeted
Interested in studying for a PhD or MPhil at the @IMS_MRL - don't leave it too late, the deadline if you want University funding is 2nd December
Have a look now at what we can offer
👇👇👇
PhD - mrl.ims.cam.ac.uk/study-us/p…
MPhil - mrl.ims.cam.ac.uk/study-us/t…
3
3
330
Daniel Fazakerley retweeted
Our next Seminar Series talk is this Friday, at 13:00!
Our speaker is Dr Natalie Krahmer, whose talk is on Elucidating the Cell Architecture of Metabolic Liver Disease via Spatial Proteomics 💊
More info here: bit.ly/3S4p4Ww
4
4
767
Daniel Fazakerley retweeted
Genetic impairment of ketone body signalling is a prevalent contributor to human metabolic dysfunction medrxiv.org/content/10.1101/… Working with our great collaborators at Pfizer we have uncovered a common genetic contributor to metabolic ill health/
2
13
28
4,176
Daniel Fazakerley retweeted
14 Jul 2025
Interested in a pretty cool postdoc project with Dr @HenningLanger and I? 🔥
14 Jul 2025
Hey Muscle And Metabolism Folks on Twitter, @LykkeSylow and I are looking for a Postdoc who is interested in applying for a prestigious @DDEA_Denmark fellowship with us. More details in the picture attached. Please share widely! @MYOTWlTTER
11
36
4,046
Daniel Fazakerley retweeted
7 Jul 2025
Uri is a brilliant and creative scientist working on super important and challenging research questions - he’s also a bloody nice guy. I hope his message spreads wide and far to highlight the absolute madness many of our US colleagues are going through at the moment. Please RT 🙏
1
3
19
2,381
Daniel Fazakerley retweeted
16 May 2025
Excited to share some of our work on ubiquitin at this seminar!
1
3
7
1,213
Daniel Fazakerley retweeted
12 May 2025
Thanks to our amazing collaborators:
@TVPLab @ThomasKriegLab @Mito_Redox @DPhaz and @AstraZeneca teams. Proud of this @TheBHF -supported science!
1
1
5
296
Daniel Fazakerley retweeted
12 May 2025
🚨 New paper out from us, reveals a novel role for mitochondrial RET-ROS in #HFpEF. 🧬 ND6 mutation ➡️ 🫀 Hypertrophy 💔 Diastolic dysfunction 🏃♂️ ↓ Exercise capacity 💪 ↑ Lean mass 🍩 HFD worsened metabolism ✅ Exercise reversed many effects!
doi.org/10.1152/ajpheart.004…
3
6
30
2,162
Daniel Fazakerley retweeted
6 May 2025
🚨We're hiring!
Come join us in Belfast at @WWIEM_QUB 🔬
We're looking for a postdoc to help uncover the mechanism behind a novel genetic cause of heart failure, funded by @TheBHF.
Apply here👉 hrwebapp.qub.ac.uk/tlive_web…
Questions? Reach out via X/LinkedIn/Email!
@ProfDavidGrieve
9
11
6,428
Daniel Fazakerley retweeted
27 Apr 2025
Check out our latest paper published in Diabetes @ADA_DiabetesPro Analysis of multiple insulin actions in single muscle fibres from insulin resistant mice reveals selective defect in endogenous GLUT4 translocation diabetesjournals.org/diabete…
3
8
423
Daniel Fazakerley retweeted
28 Apr 2025
🚨 pleased to share a new preprint made possible through a great collaboration with the @melissa_skala & @SeanPalecek labs! can medium composition impact the behavior of hPSC-derived cardiomyocytes? Andy and Aaron co-led efforts to tackle this Q w/HPLM!
tinyurl.com/ux2arjw8
2
7
34
2,455
Daniel Fazakerley retweeted
11 Apr 2025
excited for a weekend of great science #ASBMB25! if you're in CHI, I encourage you to check out a session that @Derpology & I co-organized, Sat @ 930 (W176): events.rdmobile.com/Sessions… a short talk from Kyle (Sun @ 9, W178), and posters from Kim, Kyle, & Gavin (Sun @ 430, W375c)!
1
3
12
1,467
Daniel Fazakerley retweeted
8 Apr 2025
Interested in undertaking a PhD to contribute to the understanding of the links between insulin resistance and cardiovascular disease? Apply to join my lab at the RVC with this fully-funded PhD studentship.
🎓 Fully-funded PhD studentship available.
Apply now for a PhD studentship to learn from experts who produce cutting-edge research and are published in top academic journals.
Fully-funded for UK 'Home' students.
➡️ rvc.ac.uk/phd
8
7
1,813
Daniel Fazakerley retweeted
@IMS_MRL @Cambridge_Uni full-time taught MPhil in Obesity, Endocrinology and Metabolism for 2025/2026
Application deadline 4th April!!!
High quality postgrad training in physiology & pathophysiology of energy balance & metabolism.
🛜 mrl.ims.cam.ac.uk/study-us/t…
2
2
385
Daniel Fazakerley retweeted
13 Mar 2025
New! Online now: Seeing the world through the eyes of cultured cells dlvr.it/TJW8zZ
3
8
2,179
12 Mar 2025
We have a postdoc position available in our team to undertake a UKRI-funded project to develop a new cultured skeletal muscle model for studying glc metabolism and insulin action. jobs.cam.ac.uk/job/50597/ @IMS_MRL Please RT. Please email if interested.
1
20
26
4,810