PVI is the one area where RCTs have been unable to supercede anecdotes – because operator bias is so powerful.
Only two randomized trials have shown efficacy beyond PVI (CONVERGE and VENUS), yet only a minority have adopted. And multiple PWI studies show no systematic benefit when applied widely, yet the majority continue to do so in persistent patients.
The time is ripe for personalization targeting individual mechanisms, as one size has been proven to not fit all.
What’s the obsession with PWI in AF ablation? It may appear “safe & easy”
@drjohnm BUT no randomised evidence & there is downside
#TWIC Oct 10