Debbie Marks' Lab at HMS

Joined July 2021
Photos and videos
deboramarks: Will predicting viral evolution be a good thing?
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deboramarks: Should disease research focus on earlier diagnosis rather than drug discovery?
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deboramarks: Applicable to other viruses- disease X- to anticipate immune escape - no antibody data needed x.com/nthadanin/status/16505…

We’ve updated our EVEscape paper with more SARS2 retrospective evaluation and potential use-cases! biorxiv.org/content/10.1101/… Collaborators @sarahgurev @NotinPascal @nooryoussef03 @_nathanrollins @sandercbio @yaringal (@OATML_Oxford), @deboramarks, 🧵1/4
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deboramarks: RT @AlanNawzadAmin: The preprint of my work with Eli Weinstein and Debbie Marks is up! In it we show that your off-the-shelf kernel for biological sequences is probably not as flexible you thought and build alternative sequence kernels that … arxiv.org/abs/2304.03775

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deboramarks: Check out this job at Harvard Medical School: Project Manager, Predictive Modeling linkedin.com/jobs/view/35674…

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deboramarks: RT @ml4proteins: Next week on 4/11 @ 4 pm EST, we'll have @NotinPascal talk about hybrid protein language models for fitness prediction! ml4proteinengineering.com/ap…
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deboramarks: @LubanLab So naming goes by genome sequence identity?
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deboramarks: @LubanLab Why not SARS-CoV-3? What are the virology rules that I need to learn?
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deboramarks: RT @NotinPascal: We now have a dedicated repo for the initiative: github.com/OATML-Markslab/Pr…. You are aware of a relevant assay that we have not yet included? Your favorite model is not there yet? Please see the repo instructions for suggestions of new assays & models
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deboramarks: RT @NotinPascal: With 94 assays total, ProteinGym is the largest curated collection of DMS assays to assess the ability of protein models to predict the effects of mutations -- but this is just the beginning, and we will continue to add new …

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deboramarks: RT @NotinPascal: A few updates regarding the ProteinGym benchmarks! proteingym.org

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deboramarks: @jmschreiber91 Worse than that - many methods cannot discover anything because ‘benchmarks’ are just inadequate for the goal
deboramarks: RT @igisci: Happy #LGBTSTEMDay! Our artist @mpk_draws (she/they) was inspired to promote queer representation by illustrating some contemporary queer STEM researchers – keep reading to find out a little about each person pictured! 🏳️‍🌈🧵 1/6 … x.com/igisci/status/15936516…

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deboramarks: @anshulkundaje Harvard - not officially allowed whatever the funding source. Been a huge problem during Covid …
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deboramarks: @kulesatony I like Abbas,Lichtman and Pillai cos it’s v simple
deboramarks: @JohnAllenPaulos Equivalent to the white and black counters problem. Nice.
deboramarks: Looking to buy a stock of swabs for nasal samples - first use case advertised on A is 'Gun Cleaning' - what does that tell us? x.com/deboramarks/status/157…

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