Joined April 2019
- Tweets 79
- Following 124
- Followers 624
- Likes 91
4 Photos and videos
14 Jul 2022
The data is now available.
12 Jul 2022
When is the data going to be in PRIDE?
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14 Jul 2022
The latest contribution to #depmap from the team. Enjoy.
14 Jul 2022
Congratulations to the team. We hope the community find these data useful @DepMapSanger. I'd like to make special mention of the skilled & dedicated scientific technical staff @sangerinstitute and #Procan that make possible generation of these large datasets. @TechsCommit.
Cancer Dependency Map Sanger retweeted
6 Jan 2021
We're recruiting a Senior Staff Scientist to map genetic interactions to understand epistasis in health and disease. Come help lead a multidisciplinary team to tackle this fundamental challenge in our understanding of genes and genomes. jobs.sanger.ac.uk/vacancy/se… #sangerinstitute
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Cancer Dependency Map Sanger retweeted
28 Oct 2020
Grateful to have contributed to this study mapping dependencies in OSCS from Asian patients as part of @DepMapSanger. Phenomenal work from Annie Wei & Sok Cheong @reversecancer and @sangerinstitute team @fiona_fb3 @emanuelvgo stacey price @ultanmcd @jgrgilbert #depmap
28 Oct 2020
Excited to share our paper on identifying genetic vulnerabilities in oral cancer now published in @eLife. For those interested in #CRISPR and #drugdevelopment check elifesciences.org/articles/5….
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Cancer Dependency Map Sanger retweeted
19 Oct 2020
(1/5) We are delighted to share the updated Project Score database (score.depmap.sanger.ac.uk/) and accompanying paper @NAR_Open (academic.oup.com/nar/advance…). The Project Score database uses CRISPR screens to investigate cancer dependencies and prioritise candidate targets.
ALT Project Score homepage
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Cancer Dependency Map Sanger retweeted
30 Sep 2020
Elegant analysis of the mechanism underpinning WRN dependency in MSI tumours and great to see the field moving forward so rapidly. congratulations to the team involved.
30 Sep 2020
Online at @nature: "Repeat expansions confer WRN dependence in microsatellite-unstable cancers" by @nussenza and colleagues. Interesting mechanistic insights into microsatellite instability and the vulnerabilities it confers to #cancer cells nature.com/articles/s41586-0…
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23 Sep 2020
If you like DepMap this opportunity could be for you!
23 Sep 2020
Don't miss this opportunity! Opening for Head of Data Science at Mosaic Therapeutics. Mosaic is a new spin-out from the Sanger using advanced computational methods and next-generation cancer models to find new synthetic-lethal cancer targets. Please RT
jobs.sanger.ac.uk/vacancy/he…
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Cancer Dependency Map Sanger retweeted
4 Aug 2020
Good protocols are critical for advancing science. Thanks to the work of the technical team @sangerinstitute to produce these beautiful SOP for deriving and culturing tumour organoids. Includes tips, images and videos, all freely available. @TechsCommit #depmap @CancerDepMap
4 Aug 2020
A huge effort from the team to bring you our cancer organoid derivation and expansion SOP’s. We hope you find them useful @protocolsIO @Garnettlab protocols.io/view/derivation… protocols.io/view/cryopreser… protocols.io/view/thawing-an…
protocols.io/view/derivation…
protocols.io/view/passaging-…
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Cancer Dependency Map Sanger retweeted
22 Jul 2020
Nice to see this summary on using @DepMapSanger to study drug MoA from @boehmjesse and @DrFranVazquez. #depmap.
22 Jul 2020
N&V by @boehmjesse @broadinstitute on the study by @Garnettlab @sangerinstitute, using the Cancer Dependency Map for drug mechanism‐of‐action investigations --> bit.ly/2OMmFQ9 #CancerGenomics #Genomics #Pharmacogenomics
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Cancer Dependency Map Sanger retweeted
24 Jun 2020
The GDSC website (cancerrxgene.org/) has been upgraded with two new features to enhance your analysis. GDSC hosts differential drug sensitivity data across 1,000 human cancer cell lines for hundreds of anti-cancer drugs, together with genomic biomarkers of drug sensitivity.
ALT GDSC homepage
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Cancer Dependency Map Sanger retweeted
26 May 2020
This is great work by @DepMapSanger @CancerDepMap working collaboratively to bring together an integrated dataset for 800 cell lines. Have fun everyone who, like us, enjoys working with these rich datasets! #depmap #CRISPR
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Cancer Dependency Map Sanger retweeted
22 May 2020
Our review on "Genomics-guided pre-clinical development of cancer therapies", published with @SpringerNature in @NatureCancer is now out! SharedIt link: rdcu.be/b4lxF [rdcu.be]. Many thanks to coauthors @HayleyFrancies @ultanmcd. #CancerResearch
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Cancer Dependency Map Sanger retweeted
20 May 2020
CELLector is useful new tool that mines clinical data to define molecular sub-types and then maps these onto in vitro cancer models. This can help you find the right cell model for your work. Congratulation to @HannaNajgebauer @Francesco_i0ri0 and team. Part of @DepMapSanger
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Cancer Dependency Map Sanger retweeted
23 Apr 2020
My webinar on using functional genomics for cancer drug discovery is now available to view here: milner.cam.ac.uk/milner-semi…. Join me for a live Q&A at 1pm today. @DepMapSanger #depmap
22 Apr 2020
Hope you can join us for Mathew Garnett's seminar tommorow! The talk will be available online all day with a Q&A at 1pm.
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Cancer Dependency Map Sanger retweeted
21 Apr 2020
Open position for a Junior Group Leader in AI for Oncology at the Netherlands Cancer Institute. Feel free to get in touch ! @hetAVL @NKI_nl
More info here: jgl-ai4cancer.nl
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21 Apr 2020
We'll be showcasing some of the different ways we're using #depmap data for drug discovery. @Garnettlab
21 Apr 2020
Please come along if you're interested to learn how we're using functional genomics data - including CRISPR screens - to inform multiple aspects of drug discovery including target discovery and drug mechanism of action.
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23 Mar 2020
This is important work to track and prevent further transmission of #COVID19. It leverages world-class capabilities for DNA sequencing and analysis built up over decades. Thanks to the dedicated team @sangerinstitute and across the UK making this possible.
23 Mar 2020
In response to the ongoing #COVID19 pandemic, we will deploy our large-scale genome sequencing platform, alongside regional sequencing centres, to better understand the coronavirus outbreak in the UK
bit.ly/2J7XFQC
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Cancer Dependency Map Sanger retweeted
11 Mar 2020
Great career opportunity as a Senior Staff Scientist in our lab (jobs.sanger.ac.uk/vacancy/se…). Help lead our efforts using functional genomics to study genetic epistasis in cancer. A diverse and challenging role with opportunity for development. Closing date March 26th. Please RT.
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3 Mar 2020
New data release from GDSC project includes 60,434 new IC50 values from 70 additional compounds. The total dataset now includes 446,000 dose response curves for 565 drugs. All available through the GDSC data portal: @https://www.cancerrxgene.org/ #Depmap
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Cancer Dependency Map Sanger retweeted
5 Feb 2020
I'm delighted to share that I have joined @targetvalidate team as Experimental Science Director and I look forward to working more closely with the fantastic Open Targets community.
opentargets.org
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