Expert insights from Dr. Adam J. Fein on pharmaceutical economics and the drug distribution system. Contact me at afein@drugchannels.net

Joined March 2009
2,665 Photos and videos
๐–๐ก๐ฒ ๐ƒ๐จ ๐Œ๐š๐ง๐ฒ ๐„๐ฆ๐ฉ๐ฅ๐จ๐ฒ๐ž๐ซ๐ฌ ๐’๐š๐ฒ ๐“๐ก๐ž๐ฒ ๐ƒ๐จ๐งโ€™๐ญ ๐‘๐ž๐œ๐ž๐ข๐ฏ๐ž 100% ๐จ๐Ÿ ๐“๐ก๐ž๐ข๐ซ ๐๐๐Œ ๐‘๐ž๐›๐š๐ญ๐ž๐ฌ? A persistent puzzle in the pharmacy benefit world surfaced again in @psgconsults latest benefit design reports. PBMs frequently state that they pass through 95% of manufacturer rebates to their employer clients. Yet employer surveys tell a different story. According to PSG: ๐Ÿ“Š Traditional drugs โ€ข 66% of employers report receiving 100% of rebates โ€ข 34% use other arrangements ๐Ÿ“Š Specialty drugs โ€ข Only 54% report receiving 100% of rebates โ€ข Nearly half use alternative rebate structures What's striking is that we've seen similar results for many years. So what's behind the disconnect? โ€ข Are employers defining "100% of rebates" differently than PBMs? โ€ข Do guaranteed rebate arrangements create confusion about what is actually being passed through? โ€ข Will the Consolidated Appropriations Act's transparency requirements narrow this perception gap? Or is something else going on? ๐Ÿค” Download the complete reports: ๐Ÿ“˜ Trends in Drug Benefit Design Report drugch.nl/4v57nsc ๐Ÿ“˜ Trends in Specialty Drug Benefits Report drugch.nl/4vM8zRw #PBM #DrugChannels #DrugBenefits #HealthBenefits #SpecialtyPharmacy #EmployerBenefits #HealthcareTransparency
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๐“๐ก๐ž ๐“๐จ๐ฉ 15 ๐’๐ฉ๐ž๐œ๐ข๐š๐ฅ๐ญ๐ฒ ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ข๐ž๐ฌ ๐จ๐Ÿ 2025: ๐๐๐Œ-๐€๐Ÿ๐Ÿ๐ข๐ฅ๐ข๐š๐ญ๐ž๐ ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ข๐ž๐ฌ ๐ƒ๐จ๐ฆ๐ข๐ง๐š๐ญ๐ž ๐–๐ก๐ข๐ฅ๐ž ๐‡๐ž๐š๐ฅ๐ญ๐ก ๐’๐ฒ๐ฌ๐ญ๐ž๐ฆ๐ฌ ๐š๐ง๐ ๐ˆ๐ง๐๐ž๐ฉ๐ž๐ง๐๐ž๐ง๐ญ๐ฌ ๐†๐š๐ข๐ง ๐†๐ซ๐จ๐ฎ๐ง๐ (rerun) Three companies now account for two-thirds of specialty pharmacy revenues. Drug Channels Instituteโ€™s latest analysis shows that PBM-affiliated specialty pharmacies remain firmly in controlโ€”but the market is shifting at the margins: โ€ข Health systems are expanding rapidly โ€ข A handful of independents are outperforming โ€ข Traditional retail players are losing share Whatโ€™s driving these changesโ€”and where is the market headed next? We break it all down here ๐Ÿ‘‡ drugch.nl/4uliNqM #SpecialtyPharmacy #PBM #Healthcare #DrugChannels #Pharmacy
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๐Œ๐š๐ฉ๐ฉ๐ข๐ง๐  ๐•๐ž๐ซ๐ญ๐ข๐œ๐š๐ฅ ๐ˆ๐ง๐ญ๐ž๐ ๐ซ๐š๐ญ๐ข๐จ๐ง ๐ข๐ง ๐”.๐’. ๐ƒ๐ซ๐ฎ๐  ๐‚๐ก๐š๐ง๐ง๐ž๐ฅ๐ฌ: ๐ƒ๐‚๐ˆโ€™๐ฌ 2026 ๐”๐ฉ๐๐š๐ญ๐ž The biggest companies in the U.S. drug channel have spent years building sprawling, vertically integrated empires. But some are starting to unwind them. DCIโ€™s latest update maps the shifting connections across insurers, PBMs, specialty pharmacies, and healthcare servicesโ€”and reveals whoโ€™s still doubling down and who is changing course. ๐Ÿ‘‰ Where integration is expanding ๐Ÿ‘‰ Where itโ€™s quietly retreating ๐Ÿ‘‰ How these shifts affect access, dispensing, and profits See the full analysis (and the complete chart): ๐Ÿ‘‡ drugch.nl/4vvCg8Z
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๐“๐ก๐ž ๐“๐จ๐ฉ ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ฒ ๐๐ž๐ง๐ž๐Ÿ๐ข๐ญ ๐Œ๐š๐ง๐š๐ ๐ž๐ซ๐ฌ ๐จ๐Ÿ 2025: ๐Œ๐š๐ซ๐ค๐ž๐ญ ๐’๐ก๐š๐ซ๐ž ๐š๐ง๐ ๐Š๐ž๐ฒ ๐ˆ๐ง๐๐ฎ๐ฌ๐ญ๐ซ๐ฒ ๐ƒ๐ž๐ฏ๐ž๐ฅ๐จ๐ฉ๐ฆ๐ž๐ง๐ญ๐ฌ (rerun) For 2025, 80% of all equivalent prescription claims were processed by just three companies: โ€ข CVS Caremark (CVS Health) โ€ข Express Scripts Pharmacy Benefit Services (The Cigna Group) โ€ข Optum Rx (UnitedHealth Group) The Big Three still dominate, but the story is more complicated than the headline. Independent PBMs are gaining traction. But even when they win, the Big Three may still profit. Meanwhile, the emerging Net Pricing Drug Channel #NPDC is reshaping how the large PBMs generate profits, structure contracts, and justify their role. Read DCI's full analysis ๐Ÿ‘‡ drugch.nl/4vvAnsX
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๐“๐ก๐ž ๐“๐จ๐ฉ 15 ๐”.๐’. ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ข๐ž๐ฌ ๐จ๐Ÿ 2025: ๐Œ๐š๐ซ๐ค๐ž๐ญ ๐’๐ก๐š๐ซ๐ž๐ฌ ๐š๐ง๐ ๐‘๐ž๐ฏ๐ž๐ง๐ฎ๐ž๐ฌ ๐š๐ญ ๐ญ๐ก๐ž ๐๐ข๐ ๐ ๐ž๐ฌ๐ญ ๐‚๐ก๐š๐ข๐ง๐ฌ, ๐๐๐Œ๐ฌ, ๐š๐ง๐ ๐’๐ฉ๐ž๐œ๐ข๐š๐ฅ๐ญ๐ฒ ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ข๐ž๐ฌ (rerun) From Drug Channels Institute's 2026 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers: โ€ข Total prescription dispensing revenues reached $751 billion in 2025, up 10% vs. 2024. โ€ข The top 15 organizations captured nearly three-quarters of total revenues. โ€ข The four largest players account for more than half of the U.S. market. โ€ข GLP-1 drugs continue to reshape revenue mix and competitive positioning. โ€ข Vertically integrated insurer-PBM-pharmacy models are strengthening their dominance. The chart shows who made the listโ€”and how specialty and mail pharmacy revenues are driving the story. Read the full breakdown ๐Ÿ‘‡ drugch.nl/43nb1Sd #pharmacy #PBM #healthcare #drugpricing #specialtypharmacy #healthpolicy
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From @RISRxInc: ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ฒ ๐‚๐จ๐ฉ๐š๐ฒ ๐Œ๐ข๐ฌ๐ฎ๐ฌ๐ž: ๐“๐ก๐ž ๐Œ๐ฎ๐ฅ๐ญ๐ข-๐๐ข๐ฅ๐ฅ๐ข๐จ๐ง ๐ƒ๐จ๐ฅ๐ฅ๐š๐ซ ๐ˆ๐ฌ๐ฌ๐ฎ๐ž ๐‡๐ข๐๐ข๐ง๐  ๐ˆ๐ง ๐๐ฅ๐š๐ข๐ง ๐’๐ข๐ ๐ก๐ญ Request a complimentary analysis from RIS Rx: drugch.nl/49kWbz6 Read the article: drugch.nl/4o4sFDO #sponsored
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๐๐ž๐ฑ๐ญ ๐…๐ซ๐ข๐๐š๐ฒ: ๐ƒ๐ซ๐ฎ๐  ๐‚๐ก๐š๐ง๐ง๐ž๐ฅ๐ฌ 340๐ ๐ˆ๐ง๐๐ฎ๐ฌ๐ญ๐ซ๐ฒ ๐”๐ฉ๐๐š๐ญ๐ž 2026 The 340B program is at a crossroads. Legal battles. Contract pharmacy restrictions. Rebate-model proposals. Expanding state legislation. New scrutiny of program economics. Taken together, these developments are reshaping one of the most influentialโ€”and controversialโ€”parts of the U.S. drug channel. Next Friday, my colleague Tyler Novotny and I will present a live Drug Channels Institute webinar examining what these changes mean for manufacturers, covered entities, pharmacies, PBMs, employers, and other stakeholders. We'll discuss: โ€ข Will a 340B rebate model become reality? โ€ข How the Net Pricing Drug Channel could reshape 340B economics โ€ข The legal, regulatory, and legislative battles reshaping 340B โ€ข Exclusive DCI data on the contract pharmacy marketplace and its leading participants โ€ข How manufacturers are responding to the changing economics of 340B โ€ข What comes next for 340Bโ€”โ€”and the stakeholders most likely to benefit or be affected If your organization is affected by 340B, this session will help you understand what's changing, why it matters, and what may happen next. ๐Ÿ“… Friday, June 12 ๐Ÿ•› 12:00 p.m. โ€“ 1:30 p.m. ET Register here: drugch.nl/june2026 P.S. Can't attend live? Every registrant receives access to the full replay and slide deck. #340B #DrugChannels #Healthcare #Pharmacy #PBM #HealthcarePolicy
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Like it or not, the Inflation Reduction Act (IRA) is forcing unprecedented visibility into the 340B program. @edsilverman of @statnews broke the story that @EliLillyandCo is requiring #340B hospitals to submit claims data or lose access to 340B discounts. As I told Ed, this is a predictable consequence of the IRA's drug pricing provisions. The law created new pricing obligations for manufacturers, but policymakers never established a reliable way to identify which claims qualify for 340B pricing. Here's the relevant section from his article: "The issue has intensified thanks to the Inflation Reduction Act, which imposes a maximum fair price on drugs paid for by Medicare and obligates drugmakers to pay added inflation rebates in Medicare. But the requirement overlaps with the 340B program. Why? Drugmakers must offer hospitals the lower of the maximum fair price or the 340B price โ€” and pay inflation rebates only on drugs not sold at the 340B price. 'The Inflation Reduction Act is forcing transparency into the notoriously opaque 340B program,' said Adam Fein, who heads the Drug Channels Institute and tracks prescription drug pricing and insurance coverage. 'The IRAโ€™s maximum fair price requirements make it impossible to ignore the long-standing lack of visibility into 340B claims.' He noted, however, that the federal government has not created a mechanism to identify 340B claims, and the HRSA maintains that it lacks the authority to do so. 'The result is a growing compliance dilemma that Congress never intended and regulators have yet to resolve,' he said." Full article: drugch.nl/3RG15Rb
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Congratulations to @GeBaiDC on her nomination to be Assistant Secretary of U.S. Department of Health and Human Services. Ge is exceptionally knowledgeable, thoughtful, and dedicated to improving healthcare. She would be a tremendous asset in this important leadership position. drugch.nl/4dTBUC4
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๐“๐ก๐ž 340๐ ๐‚๐จ๐ง๐ญ๐ซ๐š๐œ๐ญ ๐๐ก๐š๐ซ๐ฆ๐š๐œ๐ฒ ๐Œ๐š๐ซ๐ค๐ž๐ญ ๐ข๐ง 2026: ๐€ ๐Œ๐š๐ญ๐ฎ๐ซ๐ข๐ง๐  ๐ˆ๐ง๐๐ฎ๐ฌ๐ญ๐ซ๐ฒ ๐ƒ๐จ๐ฆ๐ข๐ง๐š๐ญ๐ž๐ ๐›๐ฒ ๐๐ข๐  ๐‚๐ก๐š๐ข๐ง๐ฌ ๐š๐ง๐ ๐๐๐Œ๐ฌ The 340B program was created in 1992 as a narrow policy solution to address an unintended consequence of Medicaidโ€™s best-price provision while supporting core safety-net providers. But Drug Channels Institute's latest exclusive analysis of the 340B contract pharmacy market shows just how dramatically the programโ€™s current operations and economic incentives have diverged from that original intent. In 2026, five publicly traded mega-corporationsโ€”Cigna, CVS Health, UnitedHealth Group, Walgreens, and Walmartโ€”are capturing 77% of all 340B contract pharmacy relationships. For the full 2026 market breakdownโ€”including which companies are winning and how the market keeps consolidatingโ€”read our latest analysis on Drug Channels: ๐Ÿ‘‡ drugch.nl/4nYd6NT
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From @Kalderos: ๐ƒ๐ซ๐ฎ๐ ๐ฌ, ๐ƒ๐ข๐ฌ๐œ๐จ๐ฎ๐ง๐ญ๐ฌ ๐š๐ง๐ ๐ƒ๐š๐ญ๐š: ๐‚๐ซ๐š๐Ÿ๐ญ๐ข๐ง๐  ๐’๐ฎ๐ฌ๐ญ๐š๐ข๐ง๐š๐›๐ข๐ฅ๐ข๐ญ๐ฒ ๐ข๐ง ๐š๐ง ๐ˆ๐ฆ๐ฉ๐ž๐ซ๐Ÿ๐ž๐œ๐ญ ๐’๐ฒ๐ฌ๐ญ๐ž๐ฆ Register for "GTN Oversight: A New Standard of Transparency Is Here" (free 6/23 webinar): drugch.nl/4wPLO0a Read the article: drugch.nl/431OVEI #sponsored
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๐Œ๐š๐ซ๐ค ๐‚๐ฎ๐›๐š๐ง ๐–๐ข๐ง๐ฌ ๐ญ๐ก๐ž ๐†๐ž๐ง๐ž๐ซ๐ข๐œ ๐๐ซ๐ข๐œ๐ž ๐–๐š๐ซ (๐€๐ ๐š๐ข๐ง) ๐Ÿ† For a surprising number of generic drugs, paying cash through @costplusdrugs can be dramatically cheaper than using commercial insurance: A new article from @AnnalsofIM found: โ€ข For generic prescriptions with out-of-pocket costs above $15, nearly 80% would have been cheaper through Cost Plus Drugs. โ€ข For prescriptions with cost sharing above $100, the median patient cost dropped from $140 through insurance to just $25 through Cost Plus. Affordability directly impacts adherence and outcomes. Unfortunately, the warped incentives of the U.S. drug channel mean that many insured patients pay MORE than transparent cash pricing. Small caveat: Less than 5% of generic prescriptions had OOP<$15. Nonetheless, another reminder from Mark Cuban @mcuban that complexity is the enemy of low costs and efficiency. Full article ๐Ÿ‘‡ drugch.nl/3PFwiDs
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๐ƒ๐ซ๐ฎ๐  ๐‚๐ก๐š๐ง๐ง๐ž๐ฅ๐ฌ ๐๐ž๐ฐ๐ฌ ๐‘๐จ๐ฎ๐ง๐๐ฎ๐ฉ, ๐Œ๐š๐ฒ 2026: My $0.02 on Optum Rxโ€™s Transparency, Must-Read 340B History, PBM Unbundling Update, PA Delays, and Vegas Fun Summer unofficially kicked off last weekend. So fire up the grill and enjoy these noteworthy delicacies, seared to perfection on the Drug Channels barbeque: โ€ข Why Optum Rx Is Accelerating Its Transparency Strategy โ€ข The Most Important 340B Paper Youโ€™ll Ever Read โ€ข Blue Shield of Californiaโ€™s PBM Unbundling Plan Meets Reality โ€ข Prior Authorization: Administrative Complexity = Delayed Care Plus: The Drug Channels Institute team takes on Las Vegasโ€”with stickers! Read all the juicy details here: ๐Ÿ‘‡ drugch.nl/4nRMHBm
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๐“๐ก๐ž ๐Œ๐จ๐ฌ๐ญ ๐ˆ๐ฆ๐ฉ๐จ๐ซ๐ญ๐š๐ง๐ญ 340๐ ๐ฉ๐š๐ฉ๐ž๐ซ ๐˜๐จ๐ฎ'๐ฅ๐ฅ ๐„๐ฏ๐ž๐ซ ๐‘๐ž๐š๐ If you care about #340B policy, use the long weekend to read this outstanding new paper: "Stretching Scarce Authorizing Legislation as Far as Possible: A Legislative History of the 340B Drug Pricing Program." Sayeh Nikpay @saynikpay and her colleagues went back to the early 1990's to reconstruct the program's origins. Their research draws on interviews with 18 key participants and 175 primary source documents spanning 1990โ€“1992. Their conclusion is difficult to ignore: 340B was originally designed as a narrow policy solution to address an unintended consequence of Medicaidโ€™s best-price provision and to support core safety-net providers. But the paper makes a compelling case that todayโ€™s program extends far beyond Congressโ€™s original intent. Whether you support or oppose the current structure of 340B, this paper is essential reading for anyone who wants to understand how we got here. Read it here: drugch.nl/4dVSiTD One especially fascinating detail: The disproportionate share hospital (DSH) eligibility threshold of 11.75% was chosen to qualify two specific hospitals and secure bipartisan support from Senator Hatch and Representative Bliley. In other words, the threshold was not grounded in any broader scientific or policy rationale. Amazing.
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๐๐๐Œ ๐’๐ก๐š๐ค๐ž๐จ๐ฎ๐ญ: ๐‡๐จ๐ฐ ๐•๐ž๐ซ๐ญ๐ข๐œ๐š๐ฅ ๐ˆ๐ง๐ญ๐ž๐ ๐ซ๐š๐ญ๐ข๐จ๐ง ๐ˆ๐ฌ ๐‘๐ž๐ฌ๐ก๐š๐ฉ๐ข๐ง๐  ๐–๐ก๐š๐ญโ€™๐ฌ ๐๐ž๐ฑ๐ญ (๐•๐ˆ๐ƒ๐„๐Ž) The PBM market is entering a shakeout phase. In this short video excerpt from DCIโ€™s recent PBM Industry Update webinar, I review: โ€ข The changing market shares of the largest PBMs โ€ข Why many smaller PBMs still depend on the Big Three โ€ข How vertical integration continues to reshape the industry โ€ข Why regulation and scale pressures could accelerate consolidation We expect the PBM market five years from now to look very different from today. Watch here ๐Ÿ‘‡ youtu.be/jMA_5lttnYo?si=W5rfโ€ฆ #PBM #Healthcare #Pharmacy #DrugChannels #HealthPolicy
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๐๐ข๐ง๐ค ๐’๐ก๐ž๐ž๐ญ: ๐๐๐Œ ๐‘๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐Œ๐š๐ฒ ๐๐จ๐ฅ๐ฌ๐ญ๐ž๐ซ ๐๐ข๐  ๐“๐ก๐ซ๐ž๐ž ๐Œ๐š๐ซ๐ค๐ž๐ญ ๐๐จ๐ฌ๐ข๐ญ๐ข๐จ๐ง ๐•๐ž๐ซ๐ฌ๐ฎ๐ฌ ๐’๐ฆ๐š๐ฅ๐ฅ๐ž๐ซ ๐‚๐จ๐ฆ๐ฉ๐ž๐ญ๐ข๐ญ๐จ๐ซ๐ฌ PBM reform may not have the impact many expect. In a recent Drug Channels Institute webinar, we discussed: โ€ข How new federal transparency rules could disadvantage smaller PBMs โ€ข Why the Big Three are better positioned to adapt As transparency becomes standard, differentiation shrinks. As compensation shifts away from list prices, PBMs move toward fee-based models. (Hello, Net Pricing Drug Channel! #NPDC) The twist: these changes could reduce pressure for further legislation and ultimately strengthen the largest players. More in The Pink Sheet ๐Ÿ‘‡ drugch.nl/42uam0Y #PBM #DrugPricing #HealthcarePolicy
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From PHIL: ๐๐ซ๐จ๐ญ๐ž๐œ๐ญ๐ข๐ง๐  ๐†๐ซ๐จ๐ฌ๐ฌ-๐ญ๐จ-๐๐ž๐ญ ๐๐ž๐ซ๐Ÿ๐จ๐ซ๐ฆ๐š๐ง๐œ๐ž ๐“๐ก๐ซ๐จ๐ฎ๐ ๐ก ๐’๐ข๐ง๐ ๐ฅ๐ž-๐‚๐ก๐š๐ง๐ง๐ž๐ฅ ๐„๐œ๐จ๐ฌ๐ฒ๐ฌ๐ญ๐ž๐ฆ๐ฌ Learn more about PHILโ€™s technology solution for brands: drugch.nl/4niITZA Read the article: drugch.nl/4ny2tRS #sponsored
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๐Ÿšจ ๐ƒ๐ซ๐ฎ๐  ๐‚๐ก๐š๐ง๐ง๐ž๐ฅ๐ฌ ๐๐ž๐ฐ๐ฌ ๐‘๐จ๐ฎ๐ง๐๐ฎ๐ฉ, ๐Œ๐ข๐-๐Œ๐š๐ฒ 2026 ๐Ÿšจ Bryce Platt breaks down a timely mix of policy, pricing, and market dynamics: โ€ข Are drug launch price analyses built on flawed assumptions? โ€ข Pharmacy closures are acceleratingโ€”new data reveal where and why โ€ข The complex reality of how hospitals are paid for uncompensated care โ€ข Key differences between 340B hospitals and federal grantees โ€ข A fresh (and unexpected) take: specialty pharmacy as a luxury hotel Dive in: ๐Ÿ‘‡ drugch.nl/4tsyWdy
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๐Ÿšจ340๐ ๐ข๐ง 2026: ๐Œ๐š๐ซ๐ค๐ž๐ญ ๐’๐ก๐ข๐Ÿ๐ญ๐ฌ, ๐๐จ๐ฅ๐ข๐œ๐ฒ ๐๐š๐ญ๐ญ๐ฅ๐ž๐ฌ, ๐š๐ง๐ ๐–๐ก๐š๐ญ ๐“๐ก๐ž๐ฒ ๐Œ๐ž๐š๐ง ๐Ÿ๐จ๐ซ ๐’๐ญ๐š๐ค๐ž๐ก๐จ๐ฅ๐๐ž๐ซ๐ฌ (Live Video Webinar) ๐Ÿšจ The 340B Drug Pricing Program remains one of the most complexโ€”and contentiousโ€”parts of the U.S. drug channel. On June 12 (12:00โ€“1:30 p.m. ET), Iโ€™ll be hosting a live webinar where Iโ€™ll break down whatโ€™s really happening behind the headlines: โ€ข The economics and continued growth of 340B โ€ข DCIโ€™s latest data on contract pharmacy trends and market dynamics โ€ข How PBMs, manufacturers, and distribution strategies are evolving โ€ข Key legal, regulatory, and state policy developments โ€ข IRA implications, rebate model proposals, and oversight challenges โ€ข the growing role of employers and plan sponsors โ€ข Emerging risks and โ€”and what to watch next โ€ข And more Clear facts. Sharp analysis. Live Q&A. If 340B affects your business, you wonโ€™t want to miss this. Register ๐Ÿ‘‰ drugch.nl/june2026 #340B #DrugPricing #PBM #Pharmacy #DrugChannels
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