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Embryogenesis papers @Embryo_Papers

Interesting papers on #embryogenesis

Joined December 2020
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"oocytes of the marine ascidian Phallusia mammillata treated with the drug BI-D1870 spontaneously form cytoplasmic MT asters, or cytasters" "there is an intrinsic mechanical pattern-forming module" journals.biologists.com/jcs/…
Embryogenesis papers retweeted
Alain Chédotal@AlainChedotal
29 Apr 2021
Beautiful real time visualization of translation in drosophila embryo using Suntag and #LSFM ( MuViSPIM @luxendo and @ImarisSoftware )
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"We performed single-cell transcriptomics to define embryonic hypothalamic microglia heterogeneity and identified four microglial subsets, including a subpopulation adjacent to NSCs that was responsive to gestational cold stress." sciencedirect.com/science/ar…
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"we investigate the role of architectural constraints on evolution of B3 DNA binding domains that regulate plant embryogenesis." academic.oup.com/nar/advance…

Structural variation affecting DNA backbone interactions underlies adaptation of B3 DNA binding...

Abstract. Functional and architectural diversification of transcription factor families has played a central role in the independent evolution of complex d

academic.oup.com
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"we mapped the vertebrate developmental landscape of A-to-I RNA editing, and generated the first comprehensive atlas of editing sites in zebrafish." academic.oup.com/nar/advance…
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"Pyruvate dehydrogenase kinases (PDK1-4) inhibit the TCA cycle by phosphorylating pyruvate dehydrogenase complex (PDC)." "PDK family is dispensable for murine embryonic development and that BCKDK serves as a compensatory mechanism by inactivating PDC." sciencedirect.com/science/ar…
"we develop a single-cell TE processing pipeline, scTE, and report the expression of TEs in single cells in a range of biological contexts" nature.com/articles/s41467-0…

Identifying transposable element expression dynamics and heterogeneity during development at the...

Nature Communications - How transposable elements (TE) contribute to cell fate changes is unclear. Here, the authors generate a pipeline to quantify TE expression from single cell data. They show...

nature.com
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"Using unbiased global sequencing and directed genetic approaches focused on early mammalian development, we find that fetal liver macrophage exhibit a unique expression signature that differentiates them from erythroid and adult macrophage cells" elifesciences.org/articles/6…

EKLF/KLF1 expression defines a unique macrophage subset during mouse erythropoiesis

Mouse fetal liver macrophages that support erythroid differentiation within erythroblastic islands exhibit a unique and transient expression signature under transcriptional control of EKLF/KLF1.

elifesciences.org
"we used the electrolyte indicators CoroNa Green AM and ION Potassium Green-2 AM to directly visualise intracellular concentrations of Na and K , respectively, at each embryonic developmental stage in mouse embryos" journals.plos.org/plosone/ar…

Live visualisation of electrolytes during mouse embryonic development using electrolyte indicators

Studies have shown that some electrolytes, including Na and K , play important roles in embryonic development. However, these studies evaluated these electrolytes by using inhibitors or knockout...

journals.plos.org
Embryogenesis papers retweeted
AscidianBioCell@AscidianBioCell
5 Feb 2021
ascidian metamorphosis: from chordate body plan to invertebrate !
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Embryogenesis papers retweeted
Schuh Lab@SchuhLab
5 Feb 2021
A sperm fuses with an egg to form a zygote. After fertilization, the maternal and paternal chromosomes need to migrate and meet in middle of the zygote. Our latest work in @NatureComms reveals how this is achieved in mouse zygotes. (1/5) 🔗tinyurl.com/wghs1 @mpi_bpc
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"Embryogenesis and blastogenesis have different morphological and molecular programs" "we combine transcriptomics and microscopy to build an atlas of the molecular and morphological signatures at each developmental stage for both pathways" #tunicate sciencedirect.com/science/ar…
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Embryogenesis papers retweeted
Achim Werner@werner_achim
21 Jan 2021
Excited to share our paper describing how the DUB OTUD5 regulates embryogenesis and when misregulated results in a developmental disease. Thank you to all of our collaborators, in particular the Kastner and Rocha labs at NIH! @Nuclear_Rocha advances.sciencemag.org/cont…

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"We characterized two brain-specific L1 insertions in neurons and glia from a donor with schizophrenia" "retrotransposition occurred during early embryogenesis" #retrotransposon nature.com/articles/s41593-0…

Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Nature Neuroscience - Zhu et al. discover that in human brain there is widespread anatomic distribution of low-frequency somatic, mosaic L1 insertions, using deep whole-genome sequencing of...

nature.com
"DNMT1 Promotes Genome Methylation and Early Embryo Development in Cockroaches" #embryogenesis #DNAmethyltransferase sciencedirect.com/science/ar…
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"Through comprehensive ChRO-seq analysis we identify candidate stage-specific chromatin activity states, novel markers and enhancer hotspots during the directed differentiation." #SmallIntestine academic.oup.com/nar/advance…

Chromatin regulatory dynamics of early human small intestinal development using a directed differ...

Abstract. The establishment of the small intestinal (SI) lineage during human embryogenesis ensures functional integrity of the intestine after birth. The

academic.oup.com
"PIR-1 dephosphorylates ppp-RNAs made by cellular RNA-dependent RNA polymerases (RdRPs) and is required for the maturation of 26G-RNAs, Dicer-dependent small RNAs that regulate thousands of genes during spermatogenesis and embryogenesis." sciencedirect.com/science/ar…
Embryogenesis papers retweeted
BazziniLab@BazziniLab
6 Jan 2021
Our paper is out!! "Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability". Great team work: Santi Medina, @gopalkushawah @LuliCastell @DiezMichay @ItsOverYourHead @MajoBlancoS at @ScienceStowers and @GSSIMR rdcu.be/cc7Cw
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Embryogenesis papers retweeted
Hao Yin
@HaoYin20
9 Jan 2021
Microfluidic model (trapezoid supporting posts👍 Geltrex for cell docking) of early post-implantation human embryogenesis (epiblast lumenogenesis, symmetry breaking, gastrulation) using human #PluripotencyStemCell Dr. Jianping Fu group Nat Protoc 2021 nature.com/articles/s496-020…
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Embryogenesis papers retweeted
Rajendhran Rajakumar@Rajee_Rajakumar
29 Dec 2020
Inducible Stem-Cell-Derived #Embryos Capture Mouse #Morphogenetic Events In Vitro: Developmental #Cell #Development cell.com/developmental-cell/…
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