At @UTDallasChemBio, we design & develop novel chemo-biosynthetic and chemo-enzymatic strategies for the discovery of biologically active molecules
Joined June 2017
- Tweets 662
- Following 581
- Followers 2,504
- Likes 3,514
117 Photos and videos
Delighted to share our paper just appeared in Chemical Science on the discovery of macrocyclic peptides targeted against an RNA motif from SARS-CoV-2! Congrats to Jake, Andrew, and Abhijith @UT_Dallas
and great collab with Wedeking group @URochester_SMD
pubs.rsc.org/en/content/arti…
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Excited to share our latest paper in @J_A_C_S on a biocatalytic strategy for the stereoselective synthesis of α-pyridyl sulfides via enzymatic carbene transfer! Congrats to @Yining_Wang_ & coauthors. Great collaboration with @ASterlingChem at @UT_Dallas!
pubs.acs.org/doi/10.1021/jac…
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Job alert! We are looking to hire an Associate Director for the Center for High Throughput Reaction Discovery & Synthesis Center (HT-RDS; ht-rds.utdallas.edu/) @UT_Dallas Interested candidates should apply at: jobs.utdallas.edu/postings/3…
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X Excited to have shared our science at the 5th iCHAT conference in beautiful Villa Mondragone near Rome. Great combination of cutting-edge science, warm atmosphere, and amazing location. Kudos to Massimo Bietti and the other organizers for putting together a great event!👏
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Congrats to newly minted Dr. Bo Couture for earning his PhD degree in Chemistry @UTDallasChemBio !!👏 Bo has developed new biocatalytic strategies for stereoselective C(sp3)-H functionalization via carbene transfer. Congrats Bo and best luck with your career in pharma!
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Our best congratulations to our Andrew (now Dr. Andrew Hong) for defending his PhD thesis with flying colors this week! 🎉 🎉 Andrew will now return to the U Rochester Medical Center for resuming his medical training toward his MD/PhD degree. PhD#20 from the Fasan group!
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Honoring the exceptional women in the @FasanLab at @UT_Dallas whose insight, dedication, and curiosity elevate our work every day! Happy International Day of Women and Girls in Science to Anwita, Francesca, Michelle, Pamela, Ru, Shreya, Sophie, and Zoe! 🎉
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A great visit by Prof. Yi Lu at UT Austin as our departmental seminar speaker this past week! We really enjoyed hearing about his group's exciting work in the design of artificial enzymes and DNA-based sensors for diagnostics. Inspiring science and great discussion!
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Delighted to share our publication in @NatureComms on the computational design of generalist carbene transferases with tailored, stereodivergent selectivity! Great collab with Sagar Khare! Kudos to Zhuofan, Mary, and Xinkun and all other coauthors!
nature.com/articles/s41467-0…
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Fasan Lab retweeted
5 Aug 2025
@FasanLab @UT_Dallas develops a new powerful method for skeletal editing of complex natural products at aliphatic C-H sites by combining site-selective and tunable enzymatic hydroxylation with chemical oxidation/ring expansion. Read on: • onlinelibrary.wiley.com/doi/…
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Very grateful to Benjamin List and Kateryna Kryvous for selecting our paper on a photobiocatalytic strategy for C(sp3)-H acylation for a highlight in Synfacts!
🙏 🙏
thieme-connect.com/products/…
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Check out our paper just published in @angew_chem on a chemoenzymatic strategy for ‘skeletal editing’ of complex molecules with engineered P450s! Big congrats to John Bennett, Andrew Bortz, Zheyuan Wang, & Muhammed Fastheem for the excellent work!
onlinelibrary.wiley.com/doi/…
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Congratulations to @Yining_Wang_ in the @FasanLab at @UT_Dallas for passing his qualifying exam! He is now officially a PhD candidate! Way to go, Yining! 👏👏
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Fasan Lab retweeted
7 Aug 2025
📢📢Our lab has a #postdoc opening!! If you are interested in pursuing *exciting* research at the interface of biocatalysis, cellular signaling, structural biology, and computation chemistry, reach out to me at ambikab@umn.edu. Check out our recent work: bhagi-damodaran-lab.weebly.c…
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Kudos to our Clark summer research fellows Gianna Eckerle and Andy (Anh Triet) Tran for doing a great job at presenting their research projects at the SURP Symposium @UT_Dallas!
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Check out our paper on stereoselective synthesis of halogenated cyclopropanes via biocatalytic cyclopropanation! Kudos to lab members Ron Adukure and Muhammed Fastheem and big thanks to our collab Tay Rosenthal, Matt Robinson & team at Corteva Agriscience!
chemistry-europe.onlinelibra…
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We are hiring! Multiple postdoctoral positions are available in our lab in the areas of biocatalysis, protein engineering/design, and peptide/protein therapeutics: jobs.utdallas.edu/postings/2… Interested candidates should email the PI with CV and cover letter. Please spread the word!
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Photobiocatalytic Enantioselective Benzylic C(sp3)–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer | Journal of the American Chemical Society pubs.acs.org/doi/full/10.102…
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On the International Day of Women and Girls in Science, a big shoutout to all the women in the @FasanLab @UTDallasChemBio for their outstanding contributions to our science! Go Aanu, Anwita, Elanor, Francesca, Hiram, Mary, Marriah, Michelle, Pamela, Ru, Shreya, and Yashika!🦾🎉
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Congrats to Jadab @majhijadab , Saty, and Anwita @Anwita_Ch for their recent paper in @ACSCatalysis on a new biocatalytic strategy for the asymmetric synthesis of oxazolidinones via intramolecular C-H amination with engineered myoglobins! Great job! 🎉👏
pubs.acs.org/doi/full/10.102…
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