🤩 What a great 🔥 chapter, this
#EBJIS2024 congress in Barcelona 🇪🇸!
What a pleasure for me to belong to this magic board ✨ that includes orthopaedic surgeons and infectious diseases physicians friends from so beautiful countries that make Europe what it is: diverse, respectful, friendly, productive, and so human- and team-based!
It was an honor for me to report how
#phage therapy could help for the treatment of patients with prosthetic joint infection (
#PJI) in the era of multi-drug resistance! What a crucial question, as antimicrobial resistance is a tsunami 🌊 leading to limited treatment options, and severe individual consequences.
#Bacteriophages are clearly an option, as adjuvant, to face this huge problem. I reported the literature review that we recently published this month with the team of my colleague and friend Pr. Sebastien Lustig (see here ➡️
link.springer.com/article/10…) and presented how we managed the 4 patients who were treated at our institution Hospices Civils de Lyon - HCL 🇫🇷 with phages from
@PHAXIAM, from
@BiomX_Inc and from academic sources. Indeed, for a patient infected with a multidrug resistant Staphylococcus epidermidis and for whom no phages from the industry were available, a phage isolated by colleagues (🙏) at
@inselgruppe in Bern🇨🇭that looked to be active was then purified by the Queen Astrid military hospital in Brussels 🇧🇪 (🙏) before being mixed in an active cocktail that was successfully administered in 🇫🇷! I presented also the various therapeutic schemes we developed and currently applying depending on the patient clinical presentation. The standard exposure (Std-Ex.) is now three injections with a one week interval, a scheme that has been included, based on our experience, in the next clinical trial promoted by
@PHAXIAM. I presented also the clinical case of patients who received or maximum exposure (Max-Ex.) that includes intravenous infusons of phages and a total of 9 local injections during a therapeutic scheme of three weeks!
All of that was possible thanks to the indefectible dedication of my colleagues (🙏) and to the support of the
@FondationHCL to our program
#PHAGEinLYON_Clinic that aims to make
#phagetherapy possible and more and more common in Lyon!
We will go ahead now to publish soon our experience, and it’s absolutely sure that there will be more and more talks and works on the topic of phage therapy at
#EBJIS2025 @EBJIS_ in Bologna 🇮🇹! Our patients crucially need this development, and treating them is definitely like a piece of art 🎨 or a jazz 🎶 partition played collectively: it requires inspiration, motivation, training, interaction, improvisation and succeed in showing that it works!
🙏 Thanks to all of my friends from the board, and to the
@CapPartner team for the incredible interactions we have! Thanks to all attendees and sponsors for their enthusiasm! See you next year for another great chapter of this fantastic tale ✨!