- Starmer gets some new glasses? ‘He needs to resign!’ - Farage gets £5 million? *crickets* James O'Brien is baffled by the lack of coverage following the Reform leader's multimillion-pound 'gift' from a crypto billionaire.

Prolonged water fasting also treated seizures effectively long before this, but you’ll die if you do it forever, so the Mayo Clinic invented the ketogenic diet in 1929 as a way to achieve the same effect while keeping someone well fed. The keto diet works by raising GABA levels in the brain but doesn’t *force* synaptic GABA effects like the drugs do, so it didn’t make people as zombified as phenobarbital, a barbiturate, the then-leading treatment for seizures. Mayo invented the keto diet as an alternative to phenobarbital. In the 1970s barbiturates were largely replaced with benzodiazepines, which have a lower side effect profile, have a lower risk of fatal overdose, and are less zombifying. Big Pharma got the keto diet reclassified as for “refractory epilepsy” meaning it is the last resort when all the drugs fail, but that is not why it was invented. Keto diets likely have broad efficacy where fasting and GABAergic drugs have efficacy. They have downsides and limitations and not everyone is a good candidate for them but they are profoundly under-utilized in psychiatry.

>1938: Melanin identified as photoprotective >1974: shown to absorb broad-spectrum electromagnetic radiation >1984: confirmed as an amorphous semiconductor >2001: proven to convert radiation into usable chemical energy >2007: fungi at Chernobyl found using melanin to harvest gamma radiation > gamma radiation > the most destructive ionizing energy on earth > melanin turned it into food >2014: synthetic melanin patented for “novel EMF shielding applications” >2024: paper confirms melanin outperforms every lab-made EMF shield on the planet 86 years of published science and the medical consensus is still AVOID THE SUN & WEAR SPF-50 >the one input your body needs to build this shield is the one thing they told you to avoid >THEY KNEW

Had a very special person and dear friend see the show yesterday in our final week before we head out on tour ♥️🙏🏻 #ianmckellen #westend #shakespeare

Sleep also washes away glutamate, which accumulates throughout the day through normal energy metabolism, and even moreso when cognitive fatigue is high by end of day, via the Glymphatic system.

Depression/anxiety is the early stage/s of neurodegenerative disease This is supported by the most cutting edge understanding/research of and in neuroscience. If unaddressed these “mood disorders” can be the first step in a cascade towards neuroinflamation, cognitive decline, and eventually life threatening diseases like Alzheimer’s and Parkinson’s. (S/O to my friend @Grimhood who has been talking about this on this platform for yrs) Don’t believe me? Depression and chronic stress/anxiety are associated with an increase in inflammatory cytokines in the brain. The same cytokines (IL-6, TNF-a etc.) that are elevated in Alzheimer’s, Parkinson’s, MS and directly implicated in neuronal damage and impaired synaptic function. Depression/common mood disorders are a low grade neuroinflamatory condition. The longer this inflammation persists the higher the risk of neurodegeneration… In addition to this there are many other direct links/similarities in the pathology of mood disorders and severe neurodegenerative diseases including: Dopaminergic dysfunction (common to depression/anhedonia and Parkinson’s), Mitochondrial dysfunction (I’ve told you guys this is related to every major chronic disease and it’s true here as well), Circadian dysregulation (implicated in depression/anxiety and Alzheimer’s/MS/other serious end stage neurodegenerative disorders), Impaired neuroplasticity/neurogenesis and resulting hippocampal atrophy (depression and anxiety both lead to/are caused by deficits in BDNF and other neurotrophic factors and as a result lead to hippocampal shrinking over time; the hippocampus is one of the first brain regions to degenerate in Alzheimer’s as well and is implicated in the severe memory deficits of this disorder). So hopefully you are convinced/realize that these are not just “mood disorders” but instead and early warning sign that your brain is in distress and should be treated as such (similarly to how you would treat high blood pressure as an early warning sign of cardiovascular disease risk/progression). Want a High-Performance Brain Optimization Plan? If you’re struggling with low motivation, anxiety, brain fog, or mood swings it’s not just “in your head”- your brain is very likely signaling a deeper issue. Mainstream solutions focus on bandaiding over symptoms (at best/in those they help at all) but real longterm performance, wellbeing, and mental resilience require addressing: ✅ Neuroinflammation and mitchondrial function ✅Neurotransmitter balance and neurogenesis/synaptic plasticity ✅Circadian dysregulation and stress resilience If you’ve been spinning your wheels with generic solutions and want to actually find and address the root cause I offer 1:1 remote consultations to build a customized health optimization/biohacking strategy tailored to your specific biology/context/lifestyle. No fluff or one size fits all protocols- just high level science backed optimization. DM me or book here: buy.stripe.com/bIY4jYcnbeRP7…

We open tonight after reimagining and re-examining scenes with a freshness that make this piece ALIVE more than ever before - it feels very exciting to be bringing this to @TrafTheatre - catch us on the west end this month 💥🥳

📰 The press reviews for FILUMENA are in, and it’s safe to say this show has truly stolen the spotlight! With such enthusiastic feedback, it’s evident that this is a must-see production! 📅 NOW - Sat 19th Oct 📸 Jack Merriman 🎫 theatreroyalwindsor.co.uk/fi…

We are officially OPEN - come couch us over the next 6 weeks 🥳♥️

The most powerful drug in the world is your mind Alexander shulgin was serving in the Navy During WW2 While at sea, he had suffered a thumb injury that required surgery They did not have morphine, but they didn't tell him that A nurse handed him a glass of orange juice He looked at the bottom of the glass and noticed undisclosed crystals Assuming it was drugs, he drank the juice and fell asleep for the entire surgery It was later revealed that it was just sugar A fraction of a gram of sugar had rendered him unconscious so what happened? His mind believed he was sedated and this caused a release of endorphins (endogenous morophine), enkalephins, and GABA On a chemical level, he was on morphine Neither the body or the mind can tell the difference Your thoughts create electrical impulses and chemical reactions that can mimick any drug out there This can help you, or hurt you because the reverse is also true Negative thoughts and expectations lead to physical harm and illness One study noted patients receiving an epidural analgesic injection experienced more pain when warned it would "feel like a bee sting" compared to being told it would create a "numbing sensation" Another study noted that simply using the word "pain" instead of "cool sensation" when describing a procedure made patients perceive it as more painful You don't think the mind has anything to do with these "idiopathic", chronic mystery diseases? Get real Everything happens for a reason. Every thought leads to a physical change in the body. On a positive note, does anyone think the well documented cases of "spontaneous remission" in stage 4 cancer didn't have anything to do with the patients will to survive and heal? Of course it did I'm not saying that mindset is everything and you can just manifest your reality and heal yourself with your thoughts What I'm saying is you must be consistently mindful and aware of your thoughts because they WILL be influencing your health and performance whether you like it or not

Interstellar is my favorite movie all time and never once thought of this theory. Seriously mind blown.

Accolade – @RichmondTheatre "I have no hesitation in saying that this is a very powerful play that deserves to be seen, especially when it is as well acted as it is here." @johngro26162901 londontheatre1.com/reviews/a…

Really enjoying working with this brilliant team and great cast of humans. And bringing the tash back, obvs 🥸 Catch us on in Windsor, Richmond and a short tour 💥

Wishing Gavin Fowler (@Fowler8Gavin) and cast of Accolade a wonderful Press Night tonight. @BKL_Productions @TheatreWindsor #Accolade #UKTour

Very excited to be joining the brilliant Sean Mathias again and giving ma first cockney in too long in this 1950’s gem of a play by Emlyn Williams 🤩👊🏻 More casting still to be announced…

Both Accolade and Filumena will take to the stage at @TheatreWindsor prior to limited UK tours, under the directorship of award-winning director Sean Mathias. 🎟️ kenwright.com/

The truth will always out. Catch the brand new production of Emlyn Williams' ACCOLADE in Windsor from 31 May. 🎟 theatreroyalwindsor.co.uk/ac… @BKL_Productions