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Frontiers | Qualitative assessment of nasopharyngeal aspirates as an alternative to tracheal...

The search for novel biomarkers for respiratory diseases, especially those associated with extreme premature birth, has been a challenge over the past severa...

Frontiers | Optimizing hemostasis to prevent bleeding and reduce transfusion requirements in...

BackgroundEffective hemostatic management remained a critical challenge in neonatal and infant cardiac surgery with cardiopulmonary bypass (CPB), and a syste...

Frontiers | Clinical and genetic characteristics of children with sodium taurocholate cotransport...

IntroductionSodium taurocholate cotransporting polypeptide deficiency (NTCPD) is an autosomal recessive disorder caused by SLC10A1 gene mutations. This study...

Frontiers | Prevalence of acute watery diarrhea in vulnerable children, mothers’ knowledge, and...

BackgroundDiarrhea remains one of the leading causes of morbidity and mortality among children worldwide. Enabling mothers with knowledge and resources is es...

Frontiers | The relationship between secondhand smoke exposure in Chinese children and adolescents...

Background and objectivesExposure to second—hand smoke (SHS) can potentially influence serum uric acid levels. However, there remains a relative paucity of s...

Frontiers | A pediatric case of citrin deficiency presenting with recurrent hypertriglyceridemic...

Citrin deficiency (CD) is a rare autosomal recessive metabolic disorder caused by pathogenic variants in the SLC25A13 gene, which encodes the mitochondrial a...

Frontiers | A novel technique of a laparoscopic percutaneous guide wire for extraperitoneal...

ObjectiveTo investigate the novel technique of a laparoscopic percutaneous guide wire for extraperitoneal closure (LPEC) of a patent processus vaginalis (PPV...

Frontiers | Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulm...

BackgroundTo investigate the clinical efficacy and safety of inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dyspl...

Frontiers | Integrated meta-analysis, network pharmacology and experimental validation to explore...

Background and purposeThis study aimed to systematically analyze the clinical efficacy of traditional Chinese medicine (TCM) in treating neonatal pneumonia (...

Frontiers | Short-term risk stratification using parallel admission and reassessment features in...

ObjectiveTo develop and validate an early risk prediction model for short-term major adverse events (MAE) in pediatric intensive care unit (PICU) admissions ...

Frontiers | Multisystem hemorrhage in a very preterm infant born to a mother with immune thromboc...

BackgroundMaternal immune thrombocytopenia (ITP) may cause neonatal ITP (NITP) via transplacental IgG. Evidence in very-preterm infants remains limited.Case ...

Frontiers | Risk factors for severe Chlamydia pneumoniae pneumonia in children: a retrospective...

ObjectiveThis study aimed to investigate the clinical characteristics of Chlamydia pneumoniae pneumonia (CPP) in children and analyze the risk factors for pr...

Frontiers | Outcomes of critically ill pediatric patients after haploidentical stem cell transpla...

BackgroundHaploidentical peripheral blood hematopoietic stem cell transplantation (haploPBSCT) is increasingly performed for both malignant and nonmalignant ...

Frontiers | Clinical Spectrum, independent risk factors, and treatment outcomes of pediatric...

BackgroundPediatric arrhythmias are heterogeneous and differ from adult disease in presentation and management; evidence from geographically vast, resource-v...

Frontiers | Preoperative myocardial strain, mesenteric resistance, and aortopulmonary collateral...

IntroductionThe contribution of aortopulmonary collateral (APC) flow to pleural effusion (PE) after total cavopulmonary connection (TCPC) remains unclear. Ex...

Frontiers | Predicting neurodevelopmental outcomes in neonatal hyperbilirubinemia: a multidimensi...

ObjectiveThe long-term neurodevelopmental trajectories of neonates with hyperbilirubinemia lacking overt acute symptoms remain largely unknown. This study ai...

Frontiers | Giant rapidly involuting congenital hemangioma in a neonate: a case report

This case report presents a rare instance of a giant rapidly involuting congenital hemangioma (RICH) in a neonate. Prenatal ultrasound identified a placenta-...

Frontiers | Impact of red blood cell transfusion and transfusion strategies on clinical outcomes in...

ObjectiveTo investigate the effects of red blood cell transfusions and transfusion strategies on clinical outcomes in extremely low gestational age neonates ...

Frontiers | Quantitative ultra-micro angiography assessment of dynamic cerebral microperfusion...

IntroductionWe aimed to establish normative developmental patterns of cerebral microperfusion using ultra-micro angiography and evaluate regional microvascul...

Frontiers | Clinical characteristics, treatment, and prognosis of pediatric Vasculo-Behçet’s...

ObjectiveVasculo-Behçet’s syndrome (VBS) is a rare subtype of Behçet's syndrome (BS) characterized by vascular involvement, and its clinical profile in the p...