Cutaneous tumors - Head and neck tumors
***Same histology - Different terminology***
Chondroid syringoma: Common adnexal tumor. Malignant transformation is extremely rare.
Pleomorphic adenoma: Most common salivary gland tumor. Recurrences are common and can undergo malignant transformation.
Both have mutations in PLAG1 genes.
Dr. Ivan #USCAP2026#pathology#PathX#PathTwitter
ALT A 42-year-old male with neurofibromatosis type 1 presents with a rapidly enlarging, painful mass in his deep gluteal region. High power view demonstrating the spindle shaped and wavy nuclei characteristic of this tumor @IARCWHO
ALT A tissue fragment composed of uniform spindle cells with nuclear palisading and areas without nuclei, creating Verocay bodies (in particular centrally) (H&E). @IARCWHO
ALT Tissue fragments showing intertwining spindle cells in a net-like pattern with fibrillary stroma (Giemsa).
ALT A tissue fragment with spindle cells with elongate, sometimes wavy nuclei in a fibrillary stroma. Nuclear inclusions are a common finding (H&E). @IARCWHO
ALT A hypocellular tissue fragment with delicate fibrillary stroma and focal elongated nuclei (Giemsa). @IARCWHO
My research is available on @ResearchGate: researchgate.net/publication…
Recurrent rhinosporidiosis in a young male: A case report and its taxonomical journey
DOI: 10.4103/tp.tp_5_23