Nucleic acid chemistry, organic synthesis, bioconjugation, biomolecular drugs, DNA-nanotechnology, biosensors.
Joined March 2017
- Tweets 78
- Following 89
- Followers 658
- Likes 32
27 Photos and videos
12 Aug 2024
The work by Mads K. Skaanning and other members of our team on the self-assembly of (L)-acyclic threoninol nucleic acids into ultrasmall wireframe nanostructures was recently published in JACS. pubs.acs.org/doi/10.1021/jac…, @iNANO_AarhusUni, @Chemistry_AU
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16 Nov 2023
Jakob Smidt from our lab visited Lennart Lykke @novonordisk during his PhD studies and the collaboration resulted in a method to conjugate GLP1 to any phosphate in siRNA. See the resulting paper in Nucleic Acids Research. academic.oup.com/nar/advance…. @iNANO_AarhusUni, @Chemistry_AU
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2 Nov 2023
Reversible protection of DNA origami by a cationic disulfide polymer that is cleaved inside cells is reported in Small by Sarah Youssef @SarahYo45655307 and other members of our team. @iNANO_AarhusUni, @Chemistry, onlinelibrary.wiley.com/doi/…
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5 Oct 2023
Triplex DNA blossoms on the front cover of Advanced Materials featuring our Triplex Origami methodology. The cover art is entirely made out of real folded paper! By postdoc @MinkieWinky and PhD student Emily Tsang. Read the article here: onlinelibrary.wiley.com/doi/…
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14 Jun 2023
So far, DNA nanotech has almost exclusively relied on Watson-Crick base interactions. In our new paper in Advanced Materials, we show that Hoogsteen interactions have the same potential to organize double-stranded DNA. @iNANO_AarhusUni, @Chemistry, onlinelibrary.wiley.com/doi/…
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27 Apr 2023
Congratulations to Minke Nijenhuis for winning the excellent student or post presentation award at FNANO2023, where she presented our work on triplex origami and we also had a reunion with two former GothelfLab members Zhao Zhang and Abhichart Krissanaprasit.
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6 Apr 2023
"Automated Solid-Phase Oligo(disulfide) Synthesis" is now online in Angewandte Chemie and special thanks to Martin Frandsen and Alexander Sandahl who have led this work. onlinelibrary.wiley.com/doi/…
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3 Jan 2023
Happy to share our recent preprint on folding double-stranded DNA into designed shapes with triplex-forming oligonucleotides: chemrxiv.org/engage/chemrxiv…
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14 Jul 2020
Our latest paper on bioconjugation, that was made in collaboration with Novo Nordisk A/S, was selected for editors favourite recet articles over at OBC. pubs.rsc.org/en/content/arti…
#Gothelflab #realtimechem #NovoNordisk #ChangingDiabetes
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20 Nov 2019
Line and Malthe from the Gothelf Lab at #AarhusUni has spent the last 3 months in Copenhagen at the #BioInnovation Institute. If you're curious to hear what they've learned, you can watch at 15.30 using this link:
youtube.com/watch?v=v0OykuR2…
#Science #chemistry #bioscience
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Gothelf lab retweeted
31 May 2019
Professor Kurt Gothelf @GothelfLab: The DNA origami method will undoubtedly influence development of new medicine @AaltoUniversity @nantech2019 aalto.fi/en/news/professor-k…
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13 May 2019
A close collaboration between #NovoNordisk and our lab at #iNANO has resulted in a recent publication in #AngewandteChemie.
#Science #Chemistry #biotech
For more information and link to the article, please visit: inano.au.dk/about/news-event…
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6 May 2019
PAPER: Researchers from the Gothelf lab has recently published a mini review in #ChemBioChem on how to design probes for affinity guided protein conjugation.
#Chemistry
onlinelibrary.wiley.com/doi/…
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8 Apr 2019
PhD student Mette Riis Bakke from the @GothelfLab will be having her qualifying exam this Wednesday.
phd.scitech.au.dk/currently/…
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13 Feb 2019
Our most recent review about "Chemistries for DNA Nanotechnology" pubs.acs.org/doi/10.1021/acs…
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13 Feb 2019
Quantitative Detection of Digoxin in Plasma Using Small‐Molecule Immunoassay in a Recyclable Gravity‐Driven Microfluidic Chip - Li - - Advanced Science - Wiley Online Library onlinelibrary.wiley.com/doi/…
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8 Feb 2019
Selective delivery of doxorubicin to EGFR cancer cells by Cetuximab‐DNA conjugates - Gothelf - - ChemBioChem - Wiley Online Library onlinelibrary.wiley.com/doi/…
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8 Feb 2019
A new paper regarding affinity guided labelling by @Mortensen_M_R et al.
Stay tuned for more!
pubs.rsc.org/en/content/arti…
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15 Jan 2019
Congratulations to Dr. Line Debois Frejlev Nielsen for achieving the PhD title! We wish you all the best for the years to come! #RealTimeChem #aarhusuni #DETECT
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9 Dec 2018
Once again the Gothelf lab won the best decorated table competition at the iNANO Christmas lunch! This year we had a Christmas in space theme with Santa Kurt (Gothelf) in the sleigh and Darth Skrydstrup chasing him in the black fighter #DecoChamps #RocketDeers #iNANO #AU
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