Joined August 2020
- Tweets 71
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- Followers 1,075
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13 Photos and videos
Water is 70–80% of a cell, with our mspSA SGAG affinity grid, we capture a near atomic (<2 Å) view showing water actively driving gene transcription inside RNA Pol II. Not just background,water is part of the machinery. Now published in Molecular Cell.doi.org/10.1016/j.molcel.202…
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Feel so proud to share our new pre-print paper. In this work, we captured intact HIV-1 cores at different depths of the nucleus and resolved the structure of native nucleosome at 5.6 Å, revealing various classes and their interplay with the core. Check it out here! @GroupZhang
13 Dec 2025
In situ chromatin dynamics and HIV-1 nuclear trafficking biorxiv.org/content/10.64898… #biorxiv_micrbio
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Our method paper for HIV-1 nuclear import is out now in EMBO reports! Check it out here: doi.org/10.1038/s44319-025-0…
@GroupZhang @shen_yao10 @OxfordStrubi @NDMOxford @eBIC_Diamond @DiamondLightSou @emboreports
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So excited to share our new work of in-cell Rubisco, now published in Nature Communications, check it out! doi.org/10.1038/s41467-025-6…
@GroupZhang @Nadav_Elad @eBIC_Diamond @OxfordStrubi @NDMOxford @WeizmannScience @NatureComms
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8 Jul 2025
Our HIV-1 nuclear import study is now online in Nature Microbiology
📄 Read the paper: nature.com/articles/s41564-0…
🎥 Watch the stunning movie of the virus in action: shorturl.at/lwGo2
Huge congratulations! @OxfordStrubi @eBIC_Diamond
Our work @GroupZhang is now published in Nature Microbiology! @NatureMicrobiol Using cryo-CLEM and cryo-ET, we unveil the nuclear import of HIV-1 and the determinants of this mysterious process. Check it out! nature.com/articles/s41564-0…
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4 Jun 2025
🔥 We caught SARS-CoV-2 in the act of membrane fusion—frame by frame! Using cryoET, we reveal the entire fusion sequence in near-native conditions—and how S2-targeting antibodies slam the brakes on it.
Don’t miss it 👉 nature.com/articles/s41467-0… @OxfordStrubi @eBIC_Diamond
3 Jun 2025
Our study is out in Nature Communications! 🎉
We reveal the full sequence of SARS-CoV-2 spike-mediated membrane fusion & show how S2-targeting antibodies block it using cryoET in a near-native system.
🔬🦠 nature.com/articles/s41467-0…
#SARSCoV2 #CryoET #Virology #CryoEM #Antibodies
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12 May 2025
Excellent review charting the evolution of chromatin research—from foundational techniques to state-of-the-art in-cell structural biology via cryo-FIB milling and cryo-ET. A key resource for the chromatin and structural biology fields. doi.org/10.1016/j.sbi.2025.1…
Our new review article is finally here, and it’s a journey through time and technology of chromatin studies.🔬Now, we’re diving into the next frontier—in-cell structural biology of chromatin powered by cryo-FIB and cryo-ET! @GroupZhang @COSB_CRSB
🔗 doi.org/10.1016/j.sbi.2025.1…
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I feel very excited to share our latest work (now in preprint) on the nuclear import of HIV-1. Employing correlative cryo-ET, we captured nearly 2000 HIV-1 cores associated with the nucleus. Find more in the paper 😆
5 Mar 2025
Correlative In Situ Cryo-ET Reveals Cellular and Viral Remodeling Associated with Selective HIV-1 Core Nuclear Import biorxiv.org/content/10.1101/… #biorxiv_micrbio
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the Peijun Zhang Lab retweeted
28 Feb 2025
Excited to share our study capturing complete fusion event snapshots of SARS-CoV-2 and its inhibition by the S2 antibody WS6 via in situ cryo-ET under near-native conditions🦠.
Big thanks to Jialu Xu, Juan Shen, and Peijun Zhang.
#CryoET #SARSCoV2 #CryoEM
biorxiv.org/content/10.1101/…
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30 Jan 2025
🎉 Exciting news! We're hiring PDRAs starting May 2025, funded by a Wellcome Discovery Award!
Join our team to unravel how HIV-1 capsids exploit host cofactors during early infection & uncover what makes the pandemic HIV-1 lineage unique.
Apply now: bit.ly/4hyTBae
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28 Nov 2024
Congratulations to @miles_a_graham on winning the prestigious NDM Graduate Prize 2024 for his exceptional performance! 🎉Wishing him continued success for the rest of his PhD journey! Keep up the amazing work, Miles! 👏@eBIC_Diamond @OxfordStrubi
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28 Nov 2024
A novel cryo-EM affinity-grid approach utilizing monodispersed single-particle streptavidin on a lipid monolayer is introduced to improve particle absorption, thereby addressing challenges like preferential angular distribution rdcu.be/d1MNM @eBIC_Diamond @OxfordStrubi
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24 Oct 2024
Get online on Cell🎉: Our data have uncovered a plethora of antiviral mechanisms by AMETA, underscoring their unique properties and potential synergy in the development of ultrapotent, broad-spectrum, and durable antiviral therapeutics. @OxfordStrubi
sciencedirect.com/science/ar…
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30 Sep 2024
Congrats Prof Peijun Zhang won the annual The Center for Retrovirus Research Distinguished Research Career Award vet.osu.edu/research/center-…
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4 Sep 2024
The University of Minnesota is hiring a Research Assistant Professor for cryoEM in the Department of Biochemistry, Molecular Biology and Biophysics. The link to the post is hr.umn.edu/Jobs/Find-Job (job ID 363926).
Welcome to reach out to Luiza @luizammend with any questions
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the Peijun Zhang Lab retweeted
15 Aug 2024
Very excited to share our first work after establishing my lab in Hong Kong University @HKUniversity Tremendously grateful to the development of PACEtomo to make the data collection possible within a reasonable period of time. @RadoDanev .
nature.com/articles/s41586-0…
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10 Jul 2024
And a lovely photo on the NDM news page: Peijun Zhang elected to European Molecular Biology Organization membership ndm.ox.ac.uk/news/peijun-zha… Congrats again!
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10 Jul 2024
Many congrats👏 Prof. Peijun Zhang elected to EMBO Membership!🎉🎉@eBIC_Diamond @OxfordStrubi
Outstanding scientists elected to EMBO Membership: in EMBO’s 60th anniversary year, 100 new members and 20 associate members join the community
embo.org/press-releases/outs…
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10 Oct 2023
Exciting work! @eBIC_Diamond @OxfordStrubi Congratulations!
Our new paper is online now! doi.org/10.1038/s41467-023-4… Great thanks to everyone contributing in this work! @GroupZhang
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