Assistant Professor @Stanford, NIH K99/R00 Fellow @NIH #NCI

Joined May 2020
8 Photos and videos
Pinned Tweet
1/8 ✨Thrilled to share that our paper is now online @NatureBiotech “Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors” nature.com/articles/s41587-0… (open access): rdcu.be/fmkQp
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1/8 ✨Thrilled to share that our paper is now online @NatureBiotech “Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors” nature.com/articles/s41587-0… (open access): rdcu.be/fmkQp
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8/8 💜 We especially thank the patients and their families for participating in the clinical trials and contributing tissue samples that made this research possible. 🏛️ We also thank our funding sources, including @theNCI, @AmericanCancer, @StanfordCancer, and @StanfordMIPS.
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7/8 🙏 This project has been a long journey, and I am deeply grateful to my extraordinary postdoctoral mentors @EbenRosenthal and @GarryPNolan for their guidance and support throughout this work. 🤝 And to our wonderful collaborators @johnhickey22 @Max_Haist @Loloabn @ErnaForgoMD @marc_a_baertsch @xavi_r_c @nsvdb @poultsides and many others not on Twitter/X.
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5/8 💡 These results suggest that improving antibody therapy may require not only better targets, but also strategies to overcome spatial barriers within the tumor microenvironment.
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6/8 💡The SSP platform is broadly applicable to antibody-based therapeutics, including immune checkpoint inhibitors, antibody-drug conjugates, and multi-specific antibodies.  Incorporating SSP into early-phase clinical trials could advance the development of next-generation cancer therapeutics by uncovering mechanisms of response and resistance, guiding individualized dosing and identifying spatial biomarkers for participant stratification.
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5/8 💡 These results suggest that improving antibody therapy may require not only better targets, but also strategies to overcome spatial barriers within the tumor microenvironment.
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6/8 💡The SSP platform is broadly applicable to antibody-based therapeutics, including immune checkpoint inhibitors, antibody-drug conjugates, and multi-specific antibodies.  Incorporating SSP into early-phase clinical trials could advance the development of next-generation cancer therapeutics by uncovering mechanisms of response and resistance, guiding individualized dosing and identifying spatial biomarkers for participant stratification.
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Please RT: The Lu Lab at Stanford is hiring a postdoc in Spatial Biology & Therapeutics. Comp bio, cancer bio, and cancer therapeutics backgrounds welcome. Available immediately; start date flexible. Details in attached ad. Apply: guolanlu@stanford.edu. Lab website:med.stanford.edu/guolanlulab…
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Congratulations Joe! Wonderful news for the department, and I’m excited to see your leadership, vision, and dedication guide us into the next chapter. 🎉
We are pleased to announce the appointment of Joseph Liao, MD, as the next Chair of the Department of Urology, effective August 1. Read the full announcement from Dean Lloyd Minor: urology.stanford.edu/news/04… @liaojoe1 @StanfordMed @AmerUrological
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I’m excited to speak at the Advanced Tissue Imaging & Image Analysis Workshop at Kyoto University (Apr 13–15, 2026) on AI-powered image analysis for spatial biology. Fantastic lineup of speakers and hands-on training across multiplex imaging, 3D tissue imaging, and bioimage analysis. If you know students or postdocs working on spatial omics, imaging, or AI, please share. Details & registration: ccii.med.kyoto-u.ac.jp/en/ev… #SpatialBiology #BioimageAnalysis #MultiplexImaging #Microscopy
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Guolan Lu retweeted
Happy to share the very first manuscript from our lab. biorxiv.org/content/10.64898… Great collaborations with @AlbertHKimMDPhD @ahstegh @GuolanLu Feng Chen and Li Ding!
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