This case example of my client looked like a typical case of trauma and gut issues.
Every other treatment failed her, but a systems based approach transformed her health.
Let's unpack.
She presented with fatigue, brain fog, gut bloating, insomnia, excess weight, and anxiety.
She had exercise intolerance, bloated to all foods, and wasn't working.
But even worse, she recently lost a child and also went through a divorce.
She tried prescription medicines, a range of supplements, psychologists, weight loss coaches, and more, but nothing worked.
Eventually she was admitted to hospital with sepsis, with her C-reactive protein reaching 153mg/L.
This was a mental rock bottom for her, which lead her to try a more holistic approach.
Four weeks later, we ordered her first bloods. Annoyingly, she saw a few doctors before one was willing to order bloodwork (after sepsis..?).
Bloodwork reveal following issues:
- iron anemia
- low thyroid hormones
- elevated insulin
- inflammation
- functional metabolic acidosis
It's important to note here:
1. Iron anemia reduces brain blood perfusion and mitochondrial function - which can drive brain fog and a lack of energy.
2. A lack of iron, inflammation and elevated insulin, can all suppress thyroid hormone output.
3. Iron is needed for lipolysis (to lose fat).
4. Low iron and thyroid issues make weight gain more likely.
5. Elevated insulin interferes with bile signalling and gut motility - increasing bloating and digestive issues.
6. All of the above drives sympathetic/stress systems. Worsening trauma systems.
This can be taken further. E.g. the bloating/digestive issues causes food and water aversion - increasing nutrient and mineral depletion, and so on.
From a systems point of view, the questions are:
1. How and what order do we untangle this?
2. Practically speaking, how do we implement this?
Given the trauma, the approach requires slow and steady to begin with - lots of patience.
So this is what we did:
Step 1: iron anemia, thyroid hormone anxiety
- daily red meat
- lactoferrin, curcumin, NAC, quercetin, passionflower, spleen, myoinositol, l theanine, b complex, mg malate
Result: increased energy, more mental resilience, improved ability to take on more challenge, and improved iron, thyroid and hemoglobin output.
Step 2: weight loss
- CICO
- elimination diet
- high carb, low fat, medium protein
- starch fruits
- RDA of all micronutrients/minerals
- myoinositol, mg malate, passionflower, curcumin
- daily red meat
- daily steps
Result: weight loss, more energy, back to work, increased confidence, bloating dissipated, hunger returned, reduced insulin inflammation levels.
Step 3: increase blood volume strength
- 8 cups water daily with 1/4 tsp mg malate, 1/8 teaspoon salt
- pilates
Result: brain fog lifted, insomnia 85% gone, want to exercise returned, calmer nervous system.
Notably, a profound effect is she is now processing trauma she was avoiding dealing with - even just talking/thinking about.
Now we are transitioning away from supplements. She's stopped counting calories. We are doing a food first and exercise approach to optimise her health.
This progression does not work without considering the systems and then how to untangle them.
For example, the iron anemia wasn't solely driven by low intake, but also inflammation (up-regulating hepcidin and blocking absorption).
So addressing iron intake and inflammation simultaneously was key. Addressing this before exercise and weight loss was also key.
Some of the nuance is lost in written form by not seeing the blood, sweat and tears of a case like this along the way. You need to start low and slow with cases like this.
No single intervention would solve it. You could not replicate this process in a randomised controlled trial.
Most people would have just cast off all her symptoms as being driven by trauma. And yet, it was systems physiology which drove her health revival.
Systems physiology is king. The systems that govern your body will ultimately decide how with your improve or stay the same.