Henderson Neurodegenerative Disease Lab. Misfolded proteins, disease processes, therapeutic development. PD and AD pathogenesis 🔬đź§
Joined October 2019
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Come help us unravel the mysteries of neurodegenerative diseases!
May 12
We’re hiring a Postdoc in the Henderson Lab @ Van Andel Institute!
Join our team studying neurodegenerative disease across scales (molecular → circuits). Flexible, high-impact projects and strong mentorship.
Apply: vai.wd1.myworkdayjobs.com/en…
Please share!
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Congratulations to @_AnikaWeekes on passing her comprehensive exam! Looking forward to all the exciting research to come!
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It’s been a busy year so far in the Henderson lab! We have several new lab members to welcome—Anika and Noah as new graduate students, Aastha as a new postdoc, Sydney as a new technician, and Giang, Kelsey, and @Abbeyzuzelski who are joining us as summer fellows! Lab is bustling!
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We then used these data to gain cellular insight by inhibiting 12 kinases associated with vulnerability. Among these, inhibition of group II PAKs was highly neuroprotective in a neuron model of α-synucleinopathy. Bridge from pathology patterns to molecular targets complete!
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Bridging network and cellular biology took a large team including co-first authors @namanvatsa, Kate Brynildsen, Tommy Goralski, and Kevin Kurgat and long-time collaborator @DaniSBassett!
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Can new targets for Parkinson’s disease be identified by examining pathology patterns in the brain? We are very excited to share our latest preprint where we explore exactly that question.
biorxiv.org/content/10.1101/…
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We developed a brain-wide neuron gene expression atlas (PANGEA). The atlas can be browsed here: lume.tv/PANGEA/. Surprisingly, resilience is associated with mitochondrial pathways!
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Great Grand Challenges in Parkinson’s Disease conference @VAInstitute! @Alysa_Kasen_ and Tommy Goralski took home poster prizes. #proudpi
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